Reds vs Diamondbacks Prediction, Odds, Moneyline, Spread & Over/Under for June 6

Odds updated as of 4:21 p.m.

The MLB schedule on Friday includes the Arizona Diamondbacks taking on the Cincinnati Reds.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this game.

Diamondbacks vs Reds Game Info

• Arizona Diamondbacks (31-31) vs. Cincinnati Reds (30-33)
• Date: Friday, June 6, 2025
• Time: 7:10 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: Apple TV+

Diamondbacks vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-118) | CIN: (-100)
• Spread: ARI: -1.5 (+136) | CIN: +1.5 (-164)
• Total: 9.5 -- Over: (-110) | Under: (-110)

Diamondbacks vs Reds Probable Starting Pitchers

Probable Pitchers: Eduardo Rodríguez (Diamondbacks) - 1-3, 7.05 ERA vs Nick Lodolo (Reds) - 4-4, 3.10 ERA

This contest's pitching matchup is set, as the Diamondbacks will send Eduardo Rodriguez (1-3) to the mound, while Nick Lodolo (4-4) will get the nod for the Reds. Rodríguez's team is 3-6-0 against the spread this season in his starts. Rodriguez's team has been victorious in 33.3% of the games he's started as the moneyline favorite with a record of 2-4. The Reds have a 6-6-0 record against the spread in Lodolo's starts. The Reds are 2-4 in Lodolo's six starts this season that they were the underdog on the moneyline.

Diamondbacks vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (54.1%)

Diamondbacks vs Reds Moneyline

• Looking at the moneyline for Diamondbacks-Reds, Arizona is the favorite at -118, and Cincinnati is -100 playing at home.

Diamondbacks vs Reds Spread

• The Reds are hosting the Diamondbacks, and are +1.5 on the runline. The Reds are +136 to cover the spread, and the Diamondbacks are -164.

Diamondbacks vs Reds Over/Under

• The over/under for Diamondbacks-Reds on June 6 is 9.5. The over is -110, and the under is -110.

Bet on Arizona Diamondbacks vs. Cincinnati Reds on FanDuel today!

Diamondbacks vs Reds Betting Trends

• The Diamondbacks have come away with 19 wins in the 38 contests they have been listed as the favorites in this season.
• This season Arizona has come away with a win 15 times in 30 chances when named as a favorite of at least -118 on the moneyline.
• The Diamondbacks and their opponents have gone over the total this season in 29 of their 60 opportunities.
• The Diamondbacks have an against the spread record of 28-32-0 in 60 games with a line this season.
• The Reds have gone 16-18 in games they were listed as the moneyline underdog (winning 47.1% of those games).
• Cincinnati has gone 10-14 in games it has played as a moneyline underdog with odds of -100 or longer (41.7%).
• The Reds have had an over/under set by bookmakers 61 times, and have combined with opponents to go over the total in 25 of those games (25-34-2).
• The Reds have gone 32-29-0 ATS this season.

Diamondbacks Player Leaders

• Corbin Carroll leads Arizona in total hits (65) this season while batting .259 with 36 extra-base hits. He has an on-base percentage of .338 and a slugging percentage of .570.
• He ranks 79th in batting average, 65th in on-base percentage, and sixth in slugging among qualified hitters in MLB.
• Geraldo Perdomo leads Arizona in OBP (.373) this season, fueled by 60 hits. He's batting .275 while slugging .422.
• He ranks 43rd in batting average, 29th in on-base percentage and 83rd in slugging in MLB.
• Perdomo brings a two-game streak with at least one hit into this one. During his last five outings he is batting .143 with a double, two walks and an RBI.
• Josh Naylor leads Arizona in slugging percentage (.448) powered by 22 extra-base hits.
• Eugenio Suarez is batting .232 with a .311 OBP and 46 RBI for Arizona this season.

Reds Player Leaders

• Elly De La Cruz paces the Reds with 62 hits. He's batting .257 and slugging .452 with an on-base percentage of .338.
• Including all qualifying hitters in the majors, his batting average places him 84th, his on-base percentage ranks 65th, and he is 54th in slugging.
• TJ Friedl has a .383 on-base percentage while slugging .419. Both are team-highs. He has a batting average of .300.
• Including all qualifying players, his batting average places him 15th, his on-base percentage is 16th, and he is 88th in slugging.
• Gavin Lux has 14 doubles, a triple, a home run and 27 walks while hitting .289.
• Santiago Espinal is batting .245 with nine doubles and 15 walks.

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