Red Sox vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for May 25

Odds updated as of 1:15 p.m.

The MLB's Sunday slate includes the Boston Red Sox facing the Baltimore Orioles.

All the information you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Red Sox vs Orioles Game Info

• Boston Red Sox (27-27) vs. Baltimore Orioles (17-34)
• Date: Sunday, May 25, 2025
• Time: 1:35 p.m. ET
• Venue: Fenway Park -- Boston, Massachusetts
• Coverage: MLB Network, NESN, and MASN

Red Sox vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-130) | BAL: (+110)
• Spread: BOS: -1.5 (+155) | BAL: +1.5 (-188)
• Total: 9 -- Over: (-112) | Under: (-108)

Red Sox vs Orioles Probable Starting Pitchers

Probable Pitchers: Walker Buehler (Red Sox) - 4-1, 4.00 ERA vs Dean Kremer (Orioles) - 3-5, 5.50 ERA

This contest's pitching matchup is set, as the Red Sox will send Walker Buehler (4-1) to the mound, while Dean Kremer (3-5) will answer the bell for the Orioles. Buehler and his team are 5-2-0 ATS this season when he starts. Buehler has started four games with his team as the moneyline favorite and won each of them. When Kremer starts, the Orioles are 3-7-0 against the spread. The Orioles have been the underdog on the moneyline in five of Kremer's starts this season, and they went 1-4 in those matchups.

Red Sox vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (51.1%)

Red Sox vs Orioles Moneyline

• Looking at the moneyline for Orioles-Red Sox, Baltimore is the underdog at +110, and Boston is -130 playing at home.

Red Sox vs Orioles Spread

• The Orioles are at +1.5 on the runline against the Red Sox. The Orioles are -188 to cover the spread, and the Red Sox are +155.

Red Sox vs Orioles Over/Under

• The over/under for the Red Sox versus Orioles contest on May 25 has been set at 9, with -112 odds on the over and -108 odds on the under.

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Red Sox vs Orioles Betting Trends

• The Red Sox have been favorites in 38 games this season and have come away with the win 19 times (50%) in those contests.
• Boston has a record of 8-10 when favored by -130 or more this year.
• The Red Sox and their opponents have hit the over in 26 of their 54 games with a total set by oddsmakers this season.
• The Red Sox have posted a record of 28-26-0 against the spread this season.
• The Orioles have won 36.4% of the games this season they were the underdog on the moneyline (8-14).
• Baltimore has gone 1-7 when playing as a moneyline underdog with odds of +110 or longer (12.5%).
• In the 51 games oddsmakers have set an over/under for the Orioles, they have combined with opponents to go over the total 26 times (26-23-2).
• The Orioles have put together a 16-35-0 record against the spread this season (covering just 31.4% of the time).

Red Sox Player Leaders

• Rafael Devers leads Boston with an OBP of .412 this season while batting .297 with 40 walks and 35 runs scored. He has a slugging percentage of .550.
• Among the qualifying batters in baseball, his batting average ranks 19th, his on-base percentage ranks fifth, and he is 11th in slugging.
• Jarren Duran has hit four homers this season while driving in 33 runs. He's batting .268 this season and slugging .425 with an on-base percentage of .319.
• Among all qualified hitters, he ranks 64th in batting average, 99th in on-base percentage and 76th in slugging percentage.
• Wilyer Abreu has 45 hits this season and has a slash line of .262/.349/.517.
• Abreu has recorded at least one base hit in two straight games. During his last five outings he is hitting .235 with a double, a home run, a walk and an RBI.
• Ceddanne Rafaela is batting .226 with a .281 OBP and 19 RBI for Boston this season.

Orioles Player Leaders

• Cedric Mullins has nine doubles, 10 home runs and 23 walks while hitting .225. He's slugging .451 with an on-base percentage of .322.
• Including all the qualified hitters in the majors, his batting average puts him 136th, his on-base percentage ranks 92nd, and he is 59th in slugging.
• Ryan O'Hearn paces his team with 46 hits and a .405 on-base percentage. He has a batting average of .315 while slugging .500.
• He is currently 10th in batting average, sixth in on-base percentage and 28th in slugging percentage among all qualifying hitters.
• Adley Rutschman is batting .214 with seven doubles, a triple, five home runs and 24 walks.
• Gunnar Henderson paces his team with a .458 slugging percentage.

Red Sox vs Orioles Head to Head

• 5/24/2025: 2-1 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 5/24/2025: 6-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/23/2025: 19-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/3/2025: 8-4 BOS (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/2/2025: 3-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 3/31/2025: 8-5 BAL (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/11/2024: 5-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/10/2024: 5-3 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 9/9/2024: 12-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/18/2024: 4-2 BAL (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -122, Underdog Moneyline: +104)

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