Phillies vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for May 16

Odds updated as of 5:13 a.m.

The MLB's Friday slate includes the Philadelphia Phillies taking on the Pittsburgh Pirates.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Phillies vs Pirates Game Info

• Philadelphia Phillies (25-18) vs. Pittsburgh Pirates (15-29)
• Date: Friday, May 16, 2025
• Time: 6:45 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and SportsNet PT

Phillies vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-220) | PIT: (+184)
• Spread: PHI: -1.5 (-106) | PIT: +1.5 (-113)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Phillies vs Pirates Probable Starting Pitchers

Probable Pitchers: Ranger Suarez (Phillies) - 1-0, 5.91 ERA vs Andrew Heaney (Pirates) - 2-3, 3.15 ERA

This contest's pitching matchup is set, as the Phillies will send Ranger Suarez (1-0) to the mound, while Andrew Heaney (2-3) will get the nod for the Pirates. Suarez has a record of 1-1-0 ATS in two starts with a spread this season. Suarez's team is 1-1 this season when he starts and they're favored on the moneyline. The Pirates have gone 3-5-0 ATS in Heaney's eight starts that had a set spread. The Pirates have been the moneyline underdog in six of Heaney's starts this season, and they went 2-4 in those games.

Phillies vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (65.7%)

Phillies vs Pirates Moneyline

• Looking at the moneyline for Pirates-Phillies, Pittsburgh is the underdog at +184, and Philadelphia is -220 playing at home.

Phillies vs Pirates Spread

• The Phillies are hosting the Pirates and are favored by 1.5 runs (-106 to cover) on the runline. Pittsburgh is -113 to cover.

Phillies vs Pirates Over/Under

• The Phillies-Pirates game on May 16 has been given an over/under of 8.5 runs. The over is set at -110 and the under at -110.

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Phillies vs Pirates Betting Trends

• The Phillies have come away with 21 wins in the 35 contests they have been listed as the favorites in this season.
• This season Philadelphia has been victorious four times in five chances when named as a favorite of at least -220 on the moneyline.
• The Phillies and their opponents have gone over in 19 of their 42 games with a total set by sportsbooks this season.
• The Phillies are 21-21-0 against the spread in their 42 games with a line set by sportsbooks this season.
• The Pirates have gone 10-19 in games they were listed as the moneyline underdog (winning 34.5% of those games).
• When playing as a moneyline underdog with odds of +184 or longer, Pittsburgh has a 2-3 record (winning 40% of its games).
• The Pirates have combined with opponents to go over the total 17 times this season for a 17-24-2 record against the over/under.
• The Pirates have an 18-25-0 record ATS this season (covering 41.9% of the time).

Phillies Player Leaders

• Kyle Schwarber has 41 hits and an OBP of .393, both of which lead Philadelphia hitters this season. He has a .261 batting average and a slugging percentage of .580.
• He ranks 70th in batting average, 15th in on-base percentage, and eighth in slugging among all qualified batters in the majors.
• Bryce Harper is batting .236 with nine doubles, seven home runs and 31 walks, while slugging .422 with an on-base percentage of .358.
• Among all qualifying hitters, he is 110th in batting average, 48th in on-base percentage and 76th in slugging percentage.
• Trea Turner has an OPS of .738, fueled by an OBP of .361 and a team-best slugging percentage of .377 this season.
• Bryson Stott has three home runs, 21 RBI and a batting average of .258 this season.
• Stott heads into this game on a two-game hitting streak. In his last five games he is hitting .167 with two walks and an RBI.

Pirates Player Leaders

• Oneil Cruz paces the Pirates with 31 hits. He's batting .238 and slugging .462 with an on-base percentage of .369.
• He is 108th in batting average, 36th in on-base percentage and 51st in slugging percentage among all qualifying hitters in the majors.
• Andrew McCutchen has seven doubles, three home runs and 18 walks while hitting .254. He's slugging .385 with an on-base percentage of .352.
• Including all qualified players, he is 85th in batting average, 54th in on-base percentage and 104th in slugging percentage.
• Ke'Bryan Hayes has put up a slugging percentage of .325, a team-high for the Pirates.
• Isiah Kiner-Falefa is hitting .283 with three doubles, a triple, a home run and seven walks.

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