Phillies vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for May 10

Odds updated as of 2:11 a.m.

The Saturday slate in MLB includes a matchup between the Philadelphia Phillies and the Cleveland Guardians.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Phillies vs Guardians Game Info

• Philadelphia Phillies (22-16) vs. Cleveland Guardians (23-15)
• Date: Saturday, May 10, 2025
• Time: 6:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CLEG and NBCS-PH

Phillies vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-124) | CLE: (+106)
• Spread: PHI: -1.5 (+132) | CLE: +1.5 (-160)
• Total: 7.5 -- Over: (-122) | Under: (-100)

Phillies vs Guardians Probable Starting Pitchers

Probable Pitchers: Ranger Suarez (Phillies) - 0-0, 17.18 ERA vs Tanner Bibee (Guardians) - 3-2, 4.26 ERA

The Phillies will give the nod to Ranger Suarez and the Guardians will counter with Tanner Bibee (3-2, 4.26 ERA). Suarez and his team failed to cover the spread in his only opportunity this season as a starter. Suarez's team lost his only start as a favorite this season. The Guardians have a 3-3-0 record against the spread in Bibee's starts. The Guardians were the underdog on the moneyline for two Bibee starts this season -- they split the games.

Phillies vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (50.9%)

Phillies vs Guardians Moneyline

• Philadelphia is a -124 favorite on the moneyline, while Cleveland is a +106 underdog at home.

Phillies vs Guardians Spread

• The Phillies are at the Guardians and are favored by 1.5 runs (+132 to cover) on the runline. Cleveland is -160 to cover.

Phillies vs Guardians Over/Under

• Phillies versus Guardians on May 10 has an over/under of 7.5 runs, with the odds on the over -122 and the under set at -100.

Bet on Philadelphia Phillies vs. Cleveland Guardians on FanDuel today!

Phillies vs Guardians Betting Trends

• The Phillies have been chosen as favorites in 30 games this year and have walked away with the win 18 times (60%) in those games.
• Philadelphia has a record of 17-7 in contests when sportsbooks favor them by -124 or more on the moneyline.
• Contests with the Phillies have gone over the total set by bookmakers in 18 of 37 chances this season.
• In 37 games with a line this season, the Phillies have a mark of 19-18-0 against the spread.
• The Guardians have been the underdog on the moneyline 22 total times this season. They've finished 11-11 in those games.
• When it has played as a moneyline underdog with odds of +106 or longer, Cleveland has gone 4-7 (36.4%).
• In the 37 games bookmakers have set an over/under for the Guardians, they have combined with opponents to go over the total 21 times (21-15-1).
• The Guardians have covered 48.6% of their games this season, going 18-19-0 against the spread.

Phillies Player Leaders

• Kyle Schwarber leads Philadelphia with 35 hits and an OBP of .402 this season. He has a .257 batting average and a slugging percentage of .559.
• Among all qualifying hitters in the majors, he is 71st in batting average, ninth in on-base percentage, and eighth in slugging.
• Bryce Harper has seven doubles, six home runs and 27 walks. He's batting .229 and slugging .403 with an on-base percentage of .349.
• He ranks 112th in batting average, 55th in on-base percentage and 89th in slugging in MLB.
• Trea Turner has hit two homers with a team-high .404 SLG this season.
• Turner brings an eight-game hitting streak into this game. In his last 10 games he is batting .442 with three doubles, a home run, two walks and four RBIs.
• Bryson Stott has three home runs, 20 RBI and a batting average of .271 this season.

Guardians Player Leaders

• Steven Kwan has an on-base percentage of .394 and a slugging percentage of .460. Both lead the Guardians. He's batting .333.
• Including all the qualified hitters in the big leagues, he is fourth in batting average, 12th in on-base percentage and 49th in slugging percentage.
• Kwan brings a seven-game hitting streak into this matchup. In his last 10 games he is batting .300 with two doubles, six walks and two RBIs.
• Jose Ramirez has seven doubles, six home runs and 12 walks while batting .278. He's slugging .466 with an on-base percentage of .338.
• Including all qualifying hitters, his batting average puts him 45th, his on-base percentage is 67th, and he is 46th in slugging.
• Kyle Manzardo paces the Guardians with 25 hits.
• Carlos Santana is batting .229 with three doubles, four home runs and 16 walks.

Phillies vs Guardians Head to Head

• 5/9/2025: 6-0 CLE (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/28/2024: 4-3 CLE (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/27/2024: 8-0 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 7/26/2024: 3-1 CLE (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/23/2023: 8-5 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/22/2023: 1-0 CLE (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/21/2023: 6-5 CLE (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)

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