Phillies vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for April 28

Odds updated as of 2:11 a.m.

On Tuesday in MLB, the Philadelphia Phillies are playing the San Francisco Giants.

All the information you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Phillies vs Giants Game Info

• Philadelphia Phillies (9-19) vs. San Francisco Giants (13-15)
• Date: Tuesday, April 28, 2026
• Time: 6:40 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and NBCS-BA

Phillies vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-174) | SF: (+146)
• Spread: PHI: -1.5 (+120) | SF: +1.5 (-144)
• Total: 8 -- Over: (-106) | Under: (-114)

Phillies vs Giants Probable Starting Pitchers

Probable Pitchers: Jesús Luzardo (Phillies) - 1-3, 6.91 ERA vs Tyler Mahle (Giants) - 1-3, 5.26 ERA

The Phillies will give the nod to Jesus Luzardo (1-3, 6.91 ERA), who is eyeing win No. 2 on the season, and the Giants will counter with Tyler Mahle (1-3, 5.26 ERA). Luzardo's team has not covered in any of his five starts with a spread this season. Luzardo's team has won 25% of his starts when they are favored on the moneyline (1-3). When Mahle starts, the Giants are 2-3-0 against the spread. The Giants are 2-2 in Mahle's four starts this season that they were the underdog on the moneyline.

Phillies vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (63.3%)

Phillies vs Giants Moneyline

• Looking at the moneyline for Phillies-Giants, Philadelphia is the favorite at -174, and San Francisco is +146 playing on the road.

Phillies vs Giants Spread

• The Giants are at +1.5 on the runline against the Phillies. The Giants are -144 to cover the spread, and the Phillies are +120.

Phillies vs Giants Over/Under

• An over/under of 8 has been set for Phillies-Giants on April 28, with the over being -106 and the under -114.

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Phillies vs Giants Betting Trends

• The Phillies have been favorites in 20 games this season and have come away with the win eight times (40%) in those contests.
• Philadelphia has a record of 5-1 in contests when sportsbooks favor them by -174 or more on the moneyline.
• The Phillies and their opponents have gone over the total this season in 14 of their 28 opportunities.
• The Phillies are 5-23-0 against the spread in their 28 games that had a posted line this season.
• The Giants have been the moneyline underdog 18 total times this season. They've finished 8-10 in those games.
• San Francisco has played as a moneyline underdog of +146 or longer in only one game this season, which it won.
• The Giants have played in 28 games with an over/under set, and have combined with their opponents to go over the total 13 times (13-12-3).
• The Giants have an 11-17-0 record ATS this season (covering only 39.3% of the time).

Phillies Player Leaders

• Bryce Harper has an OPS of .845, fueled by an OBP of .345 to go with a slugging percentage of .500. He has a .260 batting average, as well.
• Among all qualifying hitters in the majors, he is 64th in batting average, 68th in on-base percentage, and 29th in slugging.
• Kyle Schwarber has 20 hits, which leads Philadelphia batters this season. He's batting .196 with 14 extra-base hits. He's also slugging .520 with an on-base percentage of .344.
• Among all qualifying hitters, he is 164th in batting average, 71st in on-base percentage and 23rd in slugging percentage.
• Schwarber brings a two-game streak with at least one hit into this contest. In his last five games he is hitting .105 with a triple, a home run, four walks and two RBIs.
• Trea Turner has collected 26 base hits, an OBP of .304 and a slugging percentage of .354 this season.
• Turner has recorded at least one base hit in three straight games. In his last five games he is batting .211 with a double, a home run, four walks and two RBIs.
• Brandon Marsh has an OPS of .795, fueled by an OBP of .323 and a team-best slugging percentage of .473 this season.

Giants Player Leaders

• Luis Arraez has a team-high .371 slugging percentage. He's batting .314 with an on-base percentage of .345.
• Including all the qualified players in the big leagues, he ranks 13th in batting average, 68th in on-base percentage and 118th in slugging percentage.
• Jung Hoo Lee's .358 OBP paces his team. He has a batting average of .313 while slugging .475.
• He is currently 14th in batting average, 44th in on-base percentage and 42nd in slugging percentage among all qualified hitters.
• Matt Chapman is hitting .283 with five doubles, a triple, a home run and 11 walks.
• Casey Schmitt leads his team with 24 hits.

Phillies vs Giants Head to Head

• 4/8/2026: 5-0 SF (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/7/2026: 6-0 SF (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/6/2026: 6-4 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/9/2025: 13-0 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/8/2025: 4-3 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 7/7/2025: 3-1 SF (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/17/2025: 6-4 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 4/16/2025: 11-4 SF (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/15/2025: 6-4 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 4/14/2025: 10-4 SF (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)

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