Padres vs Mariners Prediction, Odds, Moneyline, Spread & Over/Under for May 18

Odds updated as of 3:11 p.m.

In MLB action on Sunday, the San Diego Padres play the Seattle Mariners.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Padres vs Mariners Game Info

• San Diego Padres (27-17) vs. Seattle Mariners (25-19)
• Date: Sunday, May 18, 2025
• Time: 4:10 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA and ROOT Sports NW

Padres vs Mariners Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-142) | SEA: (+120)
• Spread: SD: -1.5 (+146) | SEA: +1.5 (-178)
• Total: 7.5 -- Over: (-106) | Under: (-114)

Padres vs Mariners Probable Starting Pitchers

Probable Pitchers: Michael King (Padres) - 4-1, 2.32 ERA vs Bryan Woo (Mariners) - 4-1, 2.84 ERA

This contest's pitching matchup is set, as the Padres will send Michael King (4-1) to the mound, while Bryan Woo (4-1) will answer the bell for the Mariners. King's team is 4-5-0 against the spread this season in his starts. When King starts a game and his team is the favorite on the moneyline, they have a record of 4-3. The Mariners have gone 4-4-0 against the spread when Woo starts. The Mariners are 2-2 in Woo's four starts this season that they were the underdog on the moneyline.

Padres vs Mariners Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (56.3%)

Padres vs Mariners Moneyline

• San Diego is a -142 favorite on the moneyline, while Seattle is a +120 underdog on the road.

Padres vs Mariners Spread

• The Mariners are at the Padres, and are +1.5 on the runline. The Mariners are +146 to cover the spread, and the Padres are -178.

Padres vs Mariners Over/Under

• The over/under for Padres-Mariners on May 18 is 7.5. The over is -106, and the under is -114.

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Padres vs Mariners Betting Trends

• The Padres have been victorious in 16, or 66.7%, of the 24 contests they have been chosen as favorites in this season.
• This year San Diego has won 12 of 18 games when listed as at least -142 on the moneyline.
• The Padres and their opponents have hit the over in 19 of their 43 games with a total set by oddsmakers this season.
• The Padres have an against the spread mark of 25-18-0 in 43 games with a line this season.
• The Mariners have been the moneyline underdog 18 total times this season. They've finished 10-8 in those games.
• Seattle has a 4-3 record (winning 57.1% of its games) when it has played as a moneyline underdog of +120 or longer.
• The Mariners have had an over/under set by bookmakers 44 times, and have combined with opponents to go over the total in 25 of those games (25-17-2).
• The Mariners have covered 50% of their games this season, going 22-22-0 against the spread.

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego in total hits (51) this season while batting .305 with 18 extra-base hits. He has an on-base percentage of .378 and a slugging percentage of .551.
• Among all qualifying hitters in the majors, he is 14th in batting average, 25th in on-base percentage, and 11th in slugging.
• Tatis hopes to build on a two-game hitting streak in this matchup. In his last five games he is batting .200 with a double, two home runs, three walks and three RBIs.
• Manny Machado is slashing .323/.392/.466 this season and leads the Padres with an OPS of .858.
• Among all qualifying players, he is sixth in batting average, 11th in on-base percentage and 46th in slugging percentage.
• Luis Arraez has collected 46 base hits, an OBP of .337 and a slugging percentage of .416 this season.
• Arraez has recorded a hit in five games in a row. In his last five games he is batting .368 with a double and a walk.
• Xander Bogaerts has three home runs, 20 RBI and a batting average of .252 this season.

Mariners Player Leaders

• Cal Raleigh paces the Mariners with 40 hits. He's batting .253 and slugging .589 with an on-base percentage of .379.
• Including all the qualifying hitters in the big leagues, his batting average ranks 86th, his on-base percentage is 22nd, and he is fifth in slugging.
• Raleigh hopes to build on a five-game hitting streak in this matchup. During his last five outings he is hitting .353 with a double, three home runs, three walks and six RBIs.
• Jorge Polanco is hitting .313 with six doubles, 10 home runs and eight walks. He's slugging .626 with an on-base percentage of .360.
• Julio Rodriguez has racked up a slugging percentage of .404, a team-high for the Mariners.
• Randy Arozarena paces his team with a .385 OBP.

Padres vs Mariners Head to Head

• 5/17/2025: 4-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 5/16/2025: 5-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/11/2024: 5-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/10/2024: 7-3 SD (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/10/2024: 2-0 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/9/2024: 8-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/9/2023: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/8/2023: 2-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/7/2023: 10-3 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/6/2023: 4-1 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)

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