Tuesday’s MLB Strikeout Props - April 21

Will Yoshinobu Yamamoto strike out more than 5.5 batters? Can Jack Kochanowicz exceed 3.5 strikeouts? See their odds and more strikeout prop odds for all pitchers in MLB play on April 21, in the article below.

Today's MLB Strikeout Props

San Diego Padres at Colorado Rockies

• Randy Vasquez (Padres): Over/Under 4.5 Ks (Over +118, Under -158) | 2026 Stats: 6.2 strikeouts per game in 4 appearances

Los Angeles Dodgers at San Francisco Giants

• Yoshinobu Yamamoto (Dodgers): Over/Under 5.5 Ks (Over +100, Under -132) | 2026 Stats: 5.2 strikeouts per game in 4 appearances
• Landen Roupp (Giants): Over/Under 4.5 Ks (Over -158, Under +118) | 2026 Stats: 6 strikeouts per game in 4 appearances

Toronto Blue Jays at Los Angeles Angels

• Patrick Corbin (Blue Jays): Over/Under 4.5 Ks (Over -106, Under -125) | 2026 Stats: 4.5 strikeouts per game in 2 appearances
• Jack Kochanowicz (Angels): Over/Under 3.5 Ks (Over +116, Under -154) | 2026 Stats: 4.5 strikeouts per game in 4 appearances

Pittsburgh Pirates at Texas Rangers

• Kumar Rocker (Rangers): Over/Under 4.5 Ks (Over -102, Under -130) | 2026 Stats: 4.7 strikeouts per game in 3 appearances
• Carmen Mlodzinski (Pirates): Over/Under 4.5 Ks (Over +102, Under -136) | 2026 Stats: 5 strikeouts per game in 4 appearances

Athletics at Seattle Mariners

• Luis Castillo (Mariners): Over/Under 5.5 Ks (Over -114, Under -114) | 2026 Stats: 4.2 strikeouts per game in 4 appearances
• Jacob Lopez (Athletics): Over/Under 5.5 Ks (Over -112, Under -118) | 2026 Stats: 4 strikeouts per game in 4 appearances

Chicago White Sox at Arizona Diamondbacks

• Sean Burke (White Sox): Over/Under 4.5 Ks (Over +132, Under -178) | 2026 Stats: 4.2 strikeouts per game in 4 appearances
• Merrill Kelly (Diamondbacks): Over/Under 4.5 Ks (Over -140, Under +106) | 2026 Stats: 3 strikeouts per game in 1 appearance