Friday’s MLB Odds, Betting Lines and Predictions - May 16

There is a lot to be excited about on today's MLB schedule, including the New York Mets squaring off against the New York Yankees. Check out at the article below, where we provide predictions for each game.
Today's MLB Odds and Predictions
Chicago White Sox at Chicago Cubs Odds, Lines & Predictions
Game Info
- When: 2:20 p.m. ET
- Where: Wrigley Field
- TV Channel: MLB Network, MARQ and CHSN
- Probable Pitchers: Cade Horton vs. Shane Smith
- Records: Cubs (25-19), White Sox (14-30)
- Cubs Moneyline Odds: -225
- White Sox Moneyline Odds: +188
numberFire Prediction
- numberFire Predicted Favorite: Cubs
- Cubs Win Probability: 61.86%
- White Sox Win Probability: 38.14%
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Cleveland Guardians at Cincinnati Reds Odds, Lines & Predictions
Game Info
- When: 6:40 p.m. ET
- Where: Great American Ball Park
- TV Channel: FDSOH and CLEG
- Probable Pitchers: Brady Singer vs. Tanner Bibee
- Records: Reds (21-24), Guardians (25-18)
- Guardians Moneyline Odds: -120
- Reds Moneyline Odds: +102
numberFire Prediction
- numberFire Predicted Favorite: Reds
- Reds Win Probability: 55.84%
- Guardians Win Probability: 44.16%
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Pittsburgh Pirates at Philadelphia Phillies Odds, Lines & Predictions
Game Info
- When: 6:45 p.m. ET
- Where: Citizens Bank Park
- TV Channel: NBCS-PH and SportsNet PT
- Probable Pitchers: Ranger Suarez vs. Andrew Heaney
- Records: Phillies (25-18), Pirates (15-29)
- Phillies Moneyline Odds: -220
- Pirates Moneyline Odds: +184
numberFire Prediction
- numberFire Predicted Favorite: Phillies
- Phillies Win Probability: 65.67%
- Pirates Win Probability: 34.33%
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Washington Nationals at Baltimore Orioles Odds, Lines & Predictions
Game Info
- When: 7:05 p.m. ET
- Where: Oriole Park at Camden Yards
- TV Channel: MASN and MASN2
- Probable Pitchers: Cade Povich vs. MacKenzie Gore
- Records: Orioles (15-27), Nationals (18-27)
- Orioles Moneyline Odds: -108
- Nationals Moneyline Odds: -108
numberFire Prediction
- numberFire Predicted Favorite: Orioles
- Orioles Win Probability: 52.40%
- Nationals Win Probability: 47.60%
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New York Mets at New York Yankees Odds, Lines & Predictions
Game Info
- When: 7:05 p.m. ET
- Where: Yankee Stadium
- TV Channel: YES and WPIX
- Probable Pitchers: Carlos Rodon vs. Tylor Megill
- Records: Yankees (25-18), Mets (28-16)
- Yankees Moneyline Odds: -134
- Mets Moneyline Odds: +116
numberFire Prediction
- numberFire Predicted Favorite: Yankees
- Yankees Win Probability: 51.90%
- Mets Win Probability: 48.10%
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Detroit Tigers at Toronto Blue Jays Odds, Lines & Predictions
Game Info
- When: 7:07 p.m. ET
- Where: Rogers Centre
- TV Channel: MLB Network, SN1 and FDSDET
- Probable Pitchers: Bowden Francis vs. Jack Flaherty
- Records: Blue Jays (21-22), Tigers (29-15)
- Tigers Moneyline Odds: -126
- Blue Jays Moneyline Odds: +108
numberFire Prediction
- numberFire Predicted Favorite: Tigers
- Tigers Win Probability: 59.47%
- Blue Jays Win Probability: 40.53%
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Tampa Bay Rays at Miami Marlins Odds, Lines & Predictions
Game Info
- When: 7:10 p.m. ET
- Where: loanDepot park
- TV Channel: FDSFL and FDSSUN
- Probable Pitchers: Max Meyer vs. Taj Bradley
- Records: Marlins (16-26), Rays (20-23)
- Marlins Moneyline Odds: -110
- Rays Moneyline Odds: -106
numberFire Prediction
- numberFire Predicted Favorite: Rays
- Rays Win Probability: 53.29%
- Marlins Win Probability: 46.71%
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Atlanta Braves at Boston Red Sox Odds, Lines & Predictions
Game Info
- When: 7:10 p.m. ET
- Where: Fenway Park
- TV Channel: MLB Network, NESN and FDSSO
- Probable Pitchers: Garrett Crochet vs. Chris Sale
- Records: Red Sox (22-23), Braves (22-22)
- Red Sox Moneyline Odds: -120
- Braves Moneyline Odds: +102
numberFire Prediction
- numberFire Predicted Favorite: Red Sox
- Red Sox Win Probability: 52.40%
- Braves Win Probability: 47.60%
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St. Louis Cardinals at Kansas City Royals Odds, Lines & Predictions
Game Info
- When: 7:40 p.m. ET
- Where: Kauffman Stadium
- TV Channel: FDSKC and FDSMW
- Probable Pitchers: Cole Ragans vs. Andre Pallante
- Records: Royals (25-20), Cardinals (24-20)
- Royals Moneyline Odds: -162
- Cardinals Moneyline Odds: +136
numberFire Prediction
- numberFire Predicted Favorite: Royals
- Royals Win Probability: 57.40%
- Cardinals Win Probability: 42.60%
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Houston Astros at Texas Rangers Odds, Lines & Predictions
Game Info
- When: 8:05 p.m. ET
- Where: Globe Life Field
- TV Channel: Apple TV+
- Probable Pitchers: Nathan Eovaldi vs. Lance McCullers
- Records: Rangers (24-21), Astros (22-21)
- Rangers Moneyline Odds: -174
- Astros Moneyline Odds: +146
numberFire Prediction
- numberFire Predicted Favorite: Rangers
- Rangers Win Probability: 58.04%
- Astros Win Probability: 41.96%
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Minnesota Twins at Milwaukee Brewers Odds, Lines & Predictions
Game Info
- When: 8:10 p.m. ET
- Where: American Family Field
- TV Channel: FDSWI and MNNT
- Probable Pitchers: Chad Patrick vs. Joe Ryan
- Records: Brewers (21-23), Twins (24-20)
- Twins Moneyline Odds: -110
- Brewers Moneyline Odds: -106
numberFire Prediction
- numberFire Predicted Favorite: Twins
- Twins Win Probability: 54.15%
- Brewers Win Probability: 45.85%
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Seattle Mariners at San Diego Padres Odds, Lines & Predictions
Game Info
- When: 9:40 p.m. ET
- Where: PETCO Park
- TV Channel: Apple TV+
- Probable Pitchers: Stephen Kolek vs. Logan Evans
- Records: Padres (27-15), Mariners (23-19)
- Padres Moneyline Odds: -148
- Mariners Moneyline Odds: +126
numberFire Prediction
- numberFire Predicted Favorite: Padres
- Padres Win Probability: 56.51%
- Mariners Win Probability: 43.49%
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Colorado Rockies at Arizona Diamondbacks Odds, Lines & Predictions
Game Info
- When: 9:40 p.m. ET
- Where: Chase Field
- TV Channel: ARID and COLR
- Probable Pitchers: Corbin Burnes vs. Carson Palmquist
- Records: Diamondbacks (23-21), Rockies (7-36)
- Diamondbacks Moneyline Odds: -405
- Rockies Moneyline Odds: +320
numberFire Prediction
- numberFire Predicted Favorite: Diamondbacks
- Diamondbacks Win Probability: 71.74%
- Rockies Win Probability: 28.26%
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Los Angeles Angels at Los Angeles Dodgers Odds, Lines & Predictions
Game Info
- When: 10:10 p.m. ET
- Where: Dodger Stadium
- TV Channel: MLB Network, SportsNet LA and FDSW
- Probable Pitchers: Dustin May vs. Jack Kochanowicz
- Records: Dodgers (29-15), Angels (17-25)
- Dodgers Moneyline Odds: -300
- Angels Moneyline Odds: +245
numberFire Prediction
- numberFire Predicted Favorite: Dodgers
- Dodgers Win Probability: 66.79%
- Angels Win Probability: 33.21%
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Athletics at San Francisco Giants Odds, Lines & Predictions
Game Info
- When: 10:15 p.m. ET
- Where: Oracle Park
- TV Channel: MLB Network, NBCS-BA and NBCS-CA
- Probable Pitchers: Logan Webb vs. JP Sears
- Records: Giants (25-19), Athletics (22-22)
- Giants Moneyline Odds: -172
- Athletics Moneyline Odds: +144
numberFire Prediction
- numberFire Predicted Favorite: Giants
- Giants Win Probability: 63.99%
- Athletics Win Probability: 36.01%
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All MLB win probability predictions and picks are according to numberFire.