Mets vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for April 21

Odds updated as of 7:11 p.m.

On Tuesday in MLB, the New York Mets are playing the Minnesota Twins.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information about this matchup.

Mets vs Twins Game Info

• New York Mets (7-15) vs. Minnesota Twins (11-11)
• Date: Tuesday, April 21, 2026
• Time: 7:10 p.m. ET
• Venue: Citi Field -- Queens, New York
• Coverage: SNY and Twins.TV

Mets vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYM: (-162) | MIN: (+136)
• Spread: NYM: -1.5 (+132) | MIN: +1.5 (-160)
• Total: 7.5 -- Over: (-104) | Under: (-118)

Mets vs Twins Probable Starting Pitchers

Probable Pitchers: Nolan McLean (Mets) - 1-1, 2.28 ERA vs Simeon Woods Richardson (Twins) - 0-3, 6.10 ERA

This contest's pitching matchup is set, as the Mets will send Nolan McLean (1-1) to the mound, while Simeon Woods Richardson (0-3) will get the nod for the Twins. McLean's team is 2-2-0 against the spread this season in his starts. When McLean starts a game and his team is the favorite on the moneyline, they have a record of 1-2. In all of Woods Richardson's four starts that had a set spread, the Twins failed to cover. The Twins were the underdog on the moneyline for three Woods Richardson starts this season -- they lost all of the games.

Mets vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mets win (61.7%)

Mets vs Twins Moneyline

• Minnesota is the underdog, +136 on the moneyline, while New York is a -162 favorite at home.

Mets vs Twins Spread

• The Twins are at the Mets, and are +1.5 on the runline. The Twins are +132 to cover the spread, and the Mets are -160.

Mets vs Twins Over/Under

• A total of 7.5 runs has been set for the Mets-Twins game on April 21, with the over available at -104 and the under at -118.

Bet on New York Mets vs. Minnesota Twins on FanDuel today!

Mets vs Twins Betting Trends

• The Mets have been chosen as favorites in 14 games this year and have walked away with the win five times (35.7%) in those games.
• This season New York has been victorious one time in six chances when named as a favorite of at least -162 on the moneyline.
• Contests with the Mets have gone over the total set by bookmakers in nine of 22 chances this season.
• The Mets have posted a record of 8-14-0 against the spread this season.
• The Twins have been the moneyline underdog 15 total times this season. They've finished 9-6 in those games.
• Minnesota has a 2-1 record (winning 66.7% of its games) when playing as a moneyline underdog of +136 or longer.
• The Twins have played in 22 games with a set over/under, and have combined with opponents to go over the total 13 times (13-9-0).
• The Twins have covered 54.5% of their games this season, going 12-10-0 against the spread.

Mets Player Leaders

• Luis Robert is hitting .257 with two doubles, two home runs and 12 walks. He has an on-base percentage of .366 and a slugging percentage of .371.
• Among qualified hitters in baseball, he is 75th in batting average, 47th in on-base percentage, and 111th in slugging.
• Robert hopes to build on a three-game hitting streak in this matchup. During his last five outings he is batting .200 with two doubles.
• Francisco Alvarez leads New York with 15 hits and an OBP of .379 this season. He's batting .268 and slugging .500.
• Among qualifying hitters, he is 60th in batting average, 31st in on-base percentage and 36th in slugging percentage.
• Francisco Lindor is batting .205 with a .307 slugging percentage and one RBI this year.
• Marcus Semien is batting .234 with a .294 OBP and eight RBI for New York this season.
• Semien has safely hit in four games in a row. During his last five outings he is hitting .375 with a double, two walks and two RBIs.

Twins Player Leaders

• Josh Bell has accumulated a team-best slugging percentage (.447) while leading the Twins in hits (20). He's batting .263 and with an on-base percentage of .352.
• Including all the qualified hitters in the majors, his batting average is 67th, his on-base percentage ranks 67th, and he is 68th in slugging.
• Bell heads into this game on a three-game hitting streak. In his last five games he is batting .250 with an RBI.
• Ryan Jeffers is hitting .278 with two doubles, a triple, two home runs and nine walks. He's slugging .463 with an on-base percentage of .391.
• Luke Keaschall has three doubles, a home run and six walks while batting .209.
• Austin Martin has three doubles, a home run and 14 walks while batting .311.

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