Mariners vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for May 12

Odds updated as of 7:11 p.m.

MLB action on Tuesday includes the Seattle Mariners facing the Houston Astros.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Mariners vs Astros Game Info

• Seattle Mariners (20-22) vs. Houston Astros (16-26)
• Date: Tuesday, May 12, 2026
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and Mariners.TV

Mariners vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-200) | HOU: (+168)
• Spread: SEA: -1.5 (-122) | HOU: +1.5 (+102)
• Total: 8.5 -- Over: (-128) | Under: (+104)

Mariners vs Astros Probable Starting Pitchers

Probable Pitchers: Bryan Woo (Mariners) - 2-2, 4.02 ERA vs Tatsuya Imai (Astros) - 1-0, 7.27 ERA

The Mariners will call on Bryan Woo (2-2) versus the Astros and Tatsuya Imai (1-0). Woo and his team are 4-4-0 ATS this season when he starts. When Woo starts a game and his team is the favorite on the moneyline, they have a record of 4-4. The Astros are 2-1-0 ATS in Imai's three starts that had a set spread. The Astros were the underdog on the moneyline for one Imai start this season -- they lost.

Mariners vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (56.3%)

Mariners vs Astros Moneyline

• The Mariners vs Astros moneyline has Seattle as a -200 favorite, while Houston is a +168 underdog at home.

Mariners vs Astros Spread

• The Mariners are favored by 1.5 runs on the road against the Astros. The Mariners are -122 to cover the spread, while the Astros are +102.

Mariners vs Astros Over/Under

• Mariners versus Astros, on May 12, has an over/under of 8.5, with the over being -128 and the under +104.

Bet on Seattle Mariners vs. Houston Astros on FanDuel today!

Mariners vs Astros Betting Trends

• The Mariners have been favorites in 38 games this season and have come away with the win 19 times (50%) in those contests.
• Oddsmakers have given Seattle the best odds of winning it has seen this season, with a -200 moneyline listed for this contest.
• The Mariners and their opponents have gone over in 18 of their 42 games with a total set by sportsbooks this season.
• The Mariners are 15-27-0 against the spread in their 42 games with a line set by sportsbooks this season.
• The Astros have gone 10-15 in games they were the underdog on the moneyline (winning 40% of those games).
• Houston has played as a moneyline underdog of +168 or longer in only two games this season, which it split 1-1.
• The Astros have played in 42 games with an over/under set, and have combined with their opponents to go over the total 26 times (26-15-1).
• The Astros have a 16-26-0 record ATS this season.

Mariners Player Leaders

• Julio Rodriguez leads Seattle in slugging percentage (.452) and total hits (46) this season. He's batting .277 with an on-base percentage of .341.
• Among all qualified hitters in baseball, his batting average ranks 47th, his on-base percentage ranks 76th, and he is 49th in slugging.
• Rodriguez will look for his sixth straight game with a hit in this contest. In his last five games he is hitting .400 with a double, three home runs, a walk and three RBIs.
• Randy Arozarena leads Seattle with an OBP of .371 this season while batting .285 with 17 walks and 27 runs scored. He's slugging .417.
• Among qualifying batters, his batting average places him 37th, his on-base percentage 37th, and his slugging percentage 74th.
• Arozarena has picked up at least one hit in five straight games. In his last five games he is batting .421 with an RBI.
• Josh Naylor is batting .248 with a .373 slugging percentage and 20 RBI this year.
• Cole Young has three home runs, 22 RBI and a batting average of .260 this season.

Astros Player Leaders

• Yordan Alvarez has a team-high OBP (.416) and slugging percentage (.628), while leading the Astros in hits (49, while batting .314).
• Including all qualifying hitters in the majors, he is 11th in batting average, fifth in on-base percentage and fifth in slugging percentage.
• Christian Walker has nine doubles, nine home runs and 16 walks while hitting .276. He's slugging .513 with an on-base percentage of .351.
• Including all qualifying players, his batting average places him 50th, his on-base percentage ranks 60th, and he is 22nd in slugging.
• Jose Altuve is batting .255 with 10 doubles, three home runs and 17 walks.
• Isaac Paredes is hitting .271 with seven doubles, three home runs and 14 walks.

Mariners vs Astros Head to Head

• 5/11/2026: 3-1 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 4/13/2026: 6-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 4/12/2026: 6-1 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 4/11/2026: 8-7 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 4/10/2026: 9-6 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/21/2025: 7-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 9/20/2025: 6-4 SEA (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/19/2025: 4-0 SEA (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 7/20/2025: 11-3 HOU (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/19/2025: 7-6 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)

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