Guardians vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 27

Odds updated as of 1:11 p.m.

On Sunday in MLB, the Boston Red Sox are up against the Cleveland Guardians.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Red Sox vs Guardians Game Info

• Boston Red Sox (15-14) vs. Cleveland Guardians (15-11)
• Date: Sunday, April 27, 2025
• Time: 1:40 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CLEG and NESN

Red Sox vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-118) | CLE: (-100)
• Spread: BOS: -1.5 (+140) | CLE: +1.5 (-170)
• Total: 7.5 -- Over: (-122) | Under: (-100)

Red Sox vs Guardians Probable Starting Pitchers

Probable Pitchers: Brayan Bello (Red Sox) - 1-0, 1.80 ERA vs Logan Allen (Guardians) - 1-1, 2.11 ERA

The Red Sox will give the ball to Brayan Bello (1-0, 1.80 ERA), who is eyeing win No. 2 on the season, and the Guardians will counter with Logan Allen (1-1, 2.11 ERA). Bello helped his team cover the spread in his only opportunity this season as a starter. Bello's team won his only start as a favorite this season. The Guardians have a 1-3-0 record against the spread in Allen's starts. The Guardians are 2-1 in Allen's three starts this season that they were the moneyline underdog.

Red Sox vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (51.3%)

Red Sox vs Guardians Moneyline

• Boston is a -118 favorite on the moneyline, while Cleveland is a -100 underdog at home.

Red Sox vs Guardians Spread

• The Red Sox are at the Guardians and are favored by 1.5 runs (+140 to cover) on the runline. Cleveland is -170 to cover.

Red Sox vs Guardians Over/Under

• A total of 7.5 runs has been set for the Red Sox-Guardians contest on April 27, with the over available at -122 and the under at -100.

Bet on Boston Red Sox vs. Cleveland Guardians on FanDuel today!

Red Sox vs Guardians Betting Trends

• The Red Sox have been victorious in 12, or 54.5%, of the 22 contests they have been chosen as favorites in this season.
• Boston has a record of 11-8 when favored by -118 or more this year.
• The Red Sox and their opponents have gone over in 13 of their 29 games with a total set by sportsbooks this season.
• The Red Sox are 14-15-0 against the spread in their 29 games that had a posted line this season.
• The Guardians have won seven of the 16 games they were the moneyline underdog this season (43.8%).
• When it has played as a moneyline underdog with odds of -100 or longer, Cleveland has a 4-7 record (winning only 36.4% of its games).
• The Guardians have played in 26 games with a set over/under, and have combined with opponents to go over the total 14 times (14-11-1).
• The Guardians have gone 12-14-0 ATS this season.

Red Sox Player Leaders

• Alexander David Bregman has 36 hits and an OBP of .402 to go with a slugging percentage of .559. All three of those stats rank first among Boston hitters this season. He has a .324 batting average, as well.
• He is 12th in batting average, 14th in on-base percentage, and 13th in slugging among all qualified hitters in MLB.
• Bregman hopes to build on a seven-game hitting streak in this matchup. During his last 10 outings he is hitting .421 with five doubles, three home runs, eight walks and 10 RBI.
• Wilyer Abreu is batting .273 with six doubles, five home runs and 17 walks, while slugging .511 with an on-base percentage of .390.
• Among qualified hitters, he ranks 52nd in batting average, 21st in on-base percentage and 29th in slugging percentage.
• Jarren Duran has collected 31 base hits, an OBP of .316 and a slugging percentage of .388 this season.
• Rafael Devers is batting .210 with a .351 OBP and 16 RBI for Boston this season.
• Devers has hit safely in two straight games. During his last five outings he is batting .188 with a double, a home run, five walks and four RBI.

Guardians Player Leaders

• Steven Kwan has a team-high OBP (.402) and slugging percentage (.505). He's batting .350.
• He ranks fourth in batting average, 14th in on-base percentage and 32nd in slugging percentage among all qualified hitters in the majors.
• Kwan heads into this game on a nine-game hitting streak. In his last 10 outings he is hitting .375 with three doubles, a home run, three walks and four RBI.
• Jose Ramirez is batting .264 with four doubles, five home runs and nine walks. He's slugging .473 with an on-base percentage of .324.
• Including all qualifying hitters, his batting average places him 61st, his on-base percentage is 78th, and he is 44th in slugging.
• Kyle Manzardo has racked up 17 hits, a team-high for the Guardians.
• Gabriel Arias is batting .272 with five doubles, four home runs and five walks.

Red Sox vs Guardians Head to Head

• 4/26/2025: 7-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/26/2025: 5-4 CLE (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 4/25/2024: 6-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 4/24/2024: 8-0 BOS (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 4/23/2024: 4-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/18/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 4/17/2024: 2-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/16/2024: 10-7 CLE (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/15/2024: 6-0 CLE (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 6/8/2023: 10-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)

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