Giants vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for April 18

Odds updated as of 4:12 p.m.

On Saturday in MLB, the San Francisco Giants are up against the Washington Nationals.

We've got you covered, in terms of the vital information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Giants vs Nationals Game Info

• San Francisco Giants (8-12) vs. Washington Nationals (9-11)
• Date: Saturday, April 18, 2026
• Time: 4:05 p.m. ET
• Venue: Nationals Park -- Washington, District of Columbia
• Coverage: Nationals.TV and NBCS-BA

Giants vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-112) | WSH: (-104)
• Spread: SF: -1.5 (+138) | WSH: +1.5 (-166)
• Total: 9.5 -- Over: (-102) | Under: (-120)

Giants vs Nationals Probable Starting Pitchers

Probable Pitchers: Adrian Houser (Giants) - 0-2, 5.06 ERA vs Cade Cavalli (Nationals) - 0-1, 4.60 ERA

The Giants will give the nod to Adrian Houser (0-2, 5.06 ERA), who is eyeing win No. 1 on the season, and the Nationals will turn to Cade Cavalli (0-1, 4.60 ERA). Houser and his team have yet to cover the spread in any of their three chances this season. Houser has yet to start a game this season when his team was the moneyline favorite. When Cavalli starts, the Nationals are 3-1-0 against the spread. The Nationals have a 1-2 record in Cavalli's three starts this season when they were the moneyline underdog.

Giants vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (53.8%)

Giants vs Nationals Moneyline

• The Giants vs Nationals moneyline has San Francisco as a -112 favorite, while Washington is a -104 underdog at home.

Giants vs Nationals Spread

• The Giants are at the Nationals and are favored by 1.5 runs on the spread. The Giants are +138 to cover the runline, with the Nationals being -166.

Giants vs Nationals Over/Under

• The over/under for the Giants versus Nationals contest on April 18 has been set at 9.5, with -102 odds on the over and -120 odds on the under.

Bet on San Francisco Giants vs. Washington Nationals on FanDuel today!

Giants vs Nationals Betting Trends

• The Giants have been victorious in two of the six contests they have been chosen as favorites in this season.
• This season San Francisco has been victorious two times in five chances when named as a favorite of at least -112 on the moneyline.
• The Giants and their opponents have hit the over in nine of their 20 games with a total set by oddsmakers this season.
• The Giants have an against the spread record of 7-13-0 in 20 games with a line this season.
• The Nationals have won nine of the 19 games they were the moneyline underdog this season (47.4%).
• Washington has gone 9-10 when it has played as a moneyline underdog with odds of -104 or longer (47.4%).
• The Nationals have played in 20 games with a set over/under, and have combined with their opponents to go over the total 14 times (14-6-0).
• The Nationals have collected a 12-8-0 record ATS this season.

Giants Player Leaders

• Luis Arraez has an OPS of .743, fueled by an OBP of .354 to go with a slugging percentage of .389. He has a .319 batting average, as well.
• Among all qualifying hitters in baseball, his batting average ranks 13th, his on-base percentage ranks 56th, and he is 91st in slugging.
• Matt Chapman has an OPS of .738, fueled by an OBP of .333 and a team-best slugging percentage of .405 this season. He's batting .291.
• Among qualifying batters, his batting average places him 36th, his on-base percentage 89th, and his slugging percentage 87th.
• Chapman takes a three-game streak with at least one hit into this contest. During his last five outings he is hitting .238 with a double and four RBIs.
• Willy Adames leads San Francisco with 21 hits. He is batting .269 this season and 13 of his hits have gone for extra bases.
• Adames has recorded at least one base hit in two games in a row. In his last five games he is batting .300 with two doubles, a home run and an RBI.
• Jung Hoo Lee has been key for San Francisco with 17 hits, an OBP of .308 plus a slugging percentage of .377.
• Lee heads into this matchup on a four-game hitting streak. During his last five outings he is hitting .368 with two doubles, two walks and an RBI.

Nationals Player Leaders

• C.J. Abrams has 24 hits with a .469 on-base percentage and a .682 slugging percentage, all club-bests for the Nationals. He's batting .364.
• Including all qualified hitters, he ranks third in batting average, while his on-base percentage is second and he is fifth in slugging.
• Abrams enters this game on an eight-game hitting streak. During his last 10 outings he is hitting .452 with three doubles, two home runs, four walks and six RBIs.
• James Wood is batting .253 with six doubles, six home runs and 14 walks. He's slugging .542 with an on-base percentage of .367.
• He ranks 83rd in batting average, 44th in on-base percentage and 25th in slugging percentage in the big leagues.
• Daylen Lile has a slugging percentage of .372, a team-high for the Nationals.
• Luis Garcia is hitting .226 with three doubles, a triple, a home run and four walks.

Giants vs Nationals Head to Head

• 4/17/2026: 10-5 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/10/2025: 8-0 WSH (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/9/2025: 4-2 WSH (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 8/8/2025: 5-0 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/25/2025: 3-2 SF (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/24/2025: 3-0 WSH (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 5/23/2025: 4-0 SF (Favorite: Nationals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/8/2024: 9-5 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/7/2024: 7-4 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/6/2024: 11-5 WSH (Favorite: Giants, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)

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