Cubs vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for June 6

Odds updated as of 9:12 p.m.

The Chicago Cubs versus the San Francisco Giants is on the MLB schedule for Saturday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information about this matchup.

Cubs vs Giants Game Info

• Chicago Cubs (33-31) vs. San Francisco Giants (26-38)
• Date: Saturday, June 6, 2026
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and NBCS-BA

Cubs vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-138) | SF: (+118)
• Spread: CHC: -1.5 (+155) | SF: +1.5 (-188)
• Total: 8.5 -- Over: (+100) | Under: (-122)

Cubs vs Giants Probable Starting Pitchers

Probable Pitchers: Ben Brown (Cubs) - 2-2, 1.92 ERA vs Landen Roupp (Giants) - 5-6, 4.22 ERA

The Cubs will call on Ben Brown (2-2) versus the Giants and Landen Roupp (5-6). Brown and his team are 3-2-0 ATS this season when he starts. Brown's team is 2-1 this season when he starts and they are the moneyline favorite. The Giants have a 4-8-0 record against the spread in Roupp's starts. The Giants are 4-4 in Roupp's eight starts this season that they were the underdog on the moneyline.

Cubs vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (60.5%)

Cubs vs Giants Moneyline

• Chicago is a -138 favorite on the moneyline, while San Francisco is a +118 underdog on the road.

Cubs vs Giants Spread

• The Giants are at +1.5 on the runline against the Cubs. The Giants are -188 to cover the spread, and the Cubs are +155.

Cubs vs Giants Over/Under

• Cubs versus Giants on June 6 has an over/under of 8.5 runs, with the odds on the over +100 and the under set at -122.

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Cubs vs Giants Betting Trends

• The Cubs have been victorious in 22, or 53.7%, of the 41 contests they have been chosen as favorites in this season.
• Chicago has a record of 13-9 when favored by -138 or more this year.
• The Cubs' games have gone over the total in 35 of their 62 opportunities.
• The Cubs are 24-38-0 against the spread in their 62 games that had a posted line this season.
• The Giants have been the moneyline underdog 42 total times this season. They've gone 15-27 in those games.
• San Francisco is 8-9 (winning 47.1% of its games) when playing as a moneyline underdog of +118 or longer.
• In the 63 games bookmakers have set an over/under for the Giants, they have combined with opponents to go over the total 32 times (32-27-4).
• The Giants have put together a 26-37-0 record against the spread this season (covering 41.3% of the time).

Cubs Player Leaders

• Nico Hoerner is hitting .250 with 14 doubles, four home runs and 29 walks. He has an on-base percentage of .333 and a slugging percentage of .353.
• Among qualified batters in the majors, he ranks 82nd in batting average, 79th in on-base percentage, and 127th in slugging.
• Ian Happ leads Chicago in total hits (53) this season while batting .235 with 28 extra-base hits. He's slugging .487 with an on-base percentage of .350.
• Among qualified hitters, he ranks 114th in batting average, 56th in on-base percentage and 31st in slugging percentage.
• Michael Busch has 55 hits this season and a team-best OBP of .368.
• Pete Crow-Armstrong is batting .248 with a .335 OBP and 30 RBI for Chicago this season.
• Crow-Armstrong takes a 10-game hitting streak into this matchup. During his last 10 outings he is batting .366 with three doubles, three home runs, three walks and seven RBIs.

Giants Player Leaders

• Luis Arraez has a .364 on-base percentage and a .439 slugging percentage, both team-best marks for the Giants. He's batting .326.
• Including all the qualified hitters in the big leagues, he ranks third in batting average, 35th in on-base percentage and 64th in slugging percentage.
• Arraez brings a six-game hitting streak into this game. In his last 10 games he is hitting .368 with three doubles, a triple, two walks and seven RBIs.
• Casey Schmitt leads his team with 65 hits. He has a batting average of .293 while slugging .559 with an on-base percentage of .325.
• Including all qualified hitters, his batting average puts him 20th, his on-base percentage ranks 94th, and he is sixth in slugging.
• Jung Hoo Lee is hitting .321 with 14 doubles, two triples, three home runs and 10 walks.
• Willy Adames is batting .250 with 18 doubles, a triple, 11 home runs and 16 walks.

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