Top 25 College Basketball Picks & Predictions Today - January 21

With 11 games on Tuesday that feature teams ranked in the Top 25 AP Poll, the contest between No. 6 Tennessee and No. 14 Mississippi State at 7:00 PM ET is one of the day's most anticipated matchups. Who do we project to emerge victorious? See our picks and predictions below.

For a breakdown of all the big games in college basketball today, check out our betting preview below.

Alabama vs. Vanderbilt

• Matchup: Vanderbilt Commodores at No. 4 Alabama Crimson Tide
• Projected Winner: Alabama (75.06% win probability)
• Spread: Alabama (-11.5)
• Time: 7:00 PM ET
• Date: January 22
• TV Channel: SEC Network

Bet on Alabama vs. Vanderbilt with FanDuel Sportsbook.

Tennessee vs. Mississippi State

• Matchup: No. 14 Mississippi State Bulldogs at No. 6 Tennessee Volunteers
• Projected Winner: Tennessee (73.69% win probability)
• Spread: Tennessee (-8.5)
• Time: 7:00 PM ET
• Date: January 22
• TV Channel: ESPN2

Bet on Tennessee vs. Mississippi State with FanDuel Sportsbook.

UConn vs. Butler

• Matchup: Butler Bulldogs at No. 19 UConn Huskies
• Projected Winner: UConn (82.87% win probability)
• Spread: UConn (-12.5)
• Time: 7:00 PM ET
• Date: January 22
• TV Channel: Fox Sports 1

Bet on UConn vs. Butler with FanDuel Sportsbook.

Purdue vs. Ohio State

• Matchup: Ohio State Buckeyes at No. 11 Purdue Boilermakers
• Projected Winner: Purdue (80.57% win probability)
• Spread: Purdue (-9.5)
• Time: 7:30 PM ET
• Date: January 22
• TV Channel: Peacock

Bet on Purdue vs. Ohio State with FanDuel Sportsbook.

Iowa State vs. UCF

• Matchup: UCF Knights at No. 3 Iowa State Cyclones
• Projected Winner: Iowa State (91.84% win probability)
• Spread: Iowa State (-15.5)
• Time: 8:00 PM ET
• Date: January 22
• TV Channel: ESPN+

Bet on Iowa State vs. UCF with FanDuel Sportsbook.

Seton Hall vs. Marquette

• Matchup: No. 10 Marquette Golden Eagles at Seton Hall Pirates
• Projected Winner: Marquette (85.07% win probability)
• Spread: Marquette (-12.5)
• Time: 8:00 PM ET
• Date: January 22
• TV Channel: Peacock

Bet on Seton Hall vs. Marquette with FanDuel Sportsbook.

SMU vs. Louisville

• Matchup: No. 25 Louisville Cardinals at SMU Mustangs
• Projected Winner: SMU (69.11% win probability)
• Spread: SMU (-1.5)
• Time: 9:00 PM ET
• Date: January 22
• TV Channel: ACC Network

Bet on SMU vs. Louisville with FanDuel Sportsbook.

West Virginia vs. Arizona State

• Matchup: Arizona State Sun Devils at No. 23 West Virginia Mountaineers
• Projected Winner: West Virginia (78.21% win probability)
• Spread: West Virginia (-8.5)
• Time: 9:00 PM ET
• Date: January 22
• TV Channel: CBS Sports Network

Bet on West Virginia vs. Arizona State with FanDuel Sportsbook.

Texas vs. Missouri

• Matchup: No. 22 Missouri Tigers at Texas Longhorns
• Projected Winner: Texas (64.85% win probability)
• Spread: Texas (-2.5)
• Time: 9:00 PM ET
• Date: January 22
• TV Channel: SEC Network

Bet on Texas vs. Missouri with FanDuel Sportsbook.

UCLA vs. Wisconsin

• Matchup: No. 18 Wisconsin Badgers at UCLA Bruins
• Projected Winner: UCLA (57.25% win probability)
• Spread: UCLA (-3.5)
• Time: 9:30 PM ET
• Date: January 22
• TV Channel: Peacock

Bet on UCLA vs. Wisconsin with FanDuel Sportsbook.

Oregon vs. Washington

• Matchup: Washington Huskies at No. 15 Oregon Ducks
• Projected Winner: Oregon (88.76% win probability)
• Spread: Oregon (-12.5)
• Time: 11:00 PM ET
• Date: January 22
• TV Channel: BTN

Bet on Oregon vs. Washington with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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