Cardinals vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for July 21

Odds updated as of 8:12 p.m.

The St. Louis Cardinals will face the Colorado Rockies in MLB action on Monday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding this matchup.

Cardinals vs Rockies Game Info

• St. Louis Cardinals (51-49) vs. Colorado Rockies (24-75)
• Date: Monday, July 21, 2025
• Time: 8:40 p.m. ET
• Venue: Coors Field -- Denver, Colorado
• Coverage: COLR and FDSMW

Cardinals vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-168) | COL: (+142)
• Spread: STL: -1.5 (-115) | COL: +1.5 (-105)
• Total: 11.5 -- Over: (-110) | Under: (-110)

Cardinals vs Rockies Probable Starting Pitchers

Probable Pitchers: Michael McGreevy (Cardinals) - 0-0, 0.00 ERA vs Austin Gomber (Rockies) - 0-3, 5.65 ERA

The probable starters are Michael McGreevy for the Cardinals and Austin Gomber (0-3) for the Rockies. McGreevy did not pitch as the moneyline favorite last season. The Rockies have a 1-5-0 record against the spread in Gomber's starts. The Rockies have a 1-5 record in Gomber's six starts this season when they were the moneyline underdog.

Cardinals vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (62.8%)

Cardinals vs Rockies Moneyline

• St. Louis is a -168 favorite on the moneyline, while Colorado is a +142 underdog at home.

Cardinals vs Rockies Spread

• The Rockies are +1.5 on the run line against the Cardinals. The Rockies are -105 to cover, and the Cardinals are -115.

Cardinals vs Rockies Over/Under

• A total of 11.5 runs has been set for the Cardinals-Rockies contest on July 21, with the over available at -110 and the under at -110.

Bet on St. Louis Cardinals vs. Colorado Rockies on FanDuel today!

Cardinals vs Rockies Betting Trends

• The Cardinals have come away with 23 wins in the 43 contests they have been listed as the favorites in this season.
• St. Louis has been listed as a favorite of -168 or more on two occasions this season and won both games.
• The Cardinals and their opponents have hit the over in 52 of their 97 games with a total set by oddsmakers this season.
• In 97 games with a line this season, the Cardinals have a mark of 52-45-0 against the spread.
• The Rockies are 22-71 in games they were listed as the moneyline underdog (winning 23.7% of those games).
• Colorado has gone 18-59 when playing as a moneyline underdog with odds of +142 or longer (23.4%).
• In the 97 games bookmakers have set an over/under for the Rockies, they have combined with opponents to go over the total 39 times (39-55-3).
• The Rockies have covered 40.2% of their games this season, going 39-58-0 ATS.

Cardinals Player Leaders

• Brendan Donovan has an OPS of .784, fueled by an OBP of .363 to go with a slugging percentage of .421. He has a .291 batting average, as well.
• Among all qualified batters in the majors, his batting average ranks 16th, his on-base percentage ranks 31st, and he is 83rd in slugging.
• Alec Burleson has 88 hits, which ranks first among St. Louis batters this season. He's batting .293 with 29 extra-base hits. He's also slugging .470 with an on-base percentage of .340.
• Among all qualified, he ranks 13th in batting average, 60th in on-base percentage and 42nd in slugging percentage.
• Burleson takes a four-game streak with at least one hit into this contest. During his last five outings he is hitting .313 with a home run, three walks and an RBI.
• Nolan Arenado has 79 hits this season and has a slash line of .241/.299/.381.
• Masyn Winn has been key for St. Louis with 89 hits, an OBP of .322 plus a slugging percentage of .383.
• Winn has hit safely in four straight games. During his last five outings he is batting .350 with a walk.

Rockies Player Leaders

• Hunter Goodman has racked up 92 hits with a .521 slugging percentage, both team-high marks for the Rockies. He's batting .279 and with an on-base percentage of .325.
• Including all the qualifying hitters in MLB, his batting average is 39th, his on-base percentage is 84th, and he is 14th in slugging.
• Jordan Beck's .328 OBP leads his team. He has a batting average of .275 while slugging .463.
• Including all qualified hitters, he is 47th in batting average, 77th in on-base percentage and 49th in slugging percentage.
• Mickey Moniak is batting .267 with 11 doubles, six triples, 14 home runs and 16 walks.
• Ryan McMahon has 15 doubles, a triple, 15 home runs and 46 walks while batting .217.

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