Cardinals vs Brewers Prediction, Odds, Moneyline, Spread & Over/Under for April 27

Odds updated as of 2:11 p.m.

MLB action on Sunday includes the St. Louis Cardinals playing the Milwaukee Brewers.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this game.

Cardinals vs Brewers Game Info

• St. Louis Cardinals (12-15) vs. Milwaukee Brewers (13-15)
• Date: Sunday, April 27, 2025
• Time: 2:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: FDSMWX and FDSWI

Cardinals vs Brewers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-110) | MIL: (-106)
• Spread: STL: +1.5 (-192) | MIL: -1.5 (+158)
• Total: 8 -- Over: (-110) | Under: (-110)

Cardinals vs Brewers Probable Starting Pitchers

Probable Pitchers: Erick Fedde (Cardinals) - 1-2, 3.33 ERA vs José Quintana (Brewers) - 3-0, 0.96 ERA

This contest's pitching matchup is set, as the Cardinals will send Erick Fedde (1-2) to the mound, while Jose Quintana (3-0) will take the ball for the Brewers. Fedde's team is 2-3-0 against the spread in his starts this season. Fedde's team lost his only start as a favorite this season. The Brewers covered in each of the three games Quintana started that had a spread set by oddsmakers. The Brewers were the underdog on the moneyline for two Quintana starts this season -- they won both.

Cardinals vs Brewers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (51.4%)

Cardinals vs Brewers Moneyline

• Looking at the moneyline for Cardinals-Brewers, St. Louis is the favorite at -110, and Milwaukee is -106 playing on the road.

Cardinals vs Brewers Spread

• The Brewers are 1.5-run favorites against the spread for this matchup with the Cardinals. The Brewers are +158 to cover, while the Cardinals are -192 to cover as a 1.5-run underdog on the runline.

Cardinals vs Brewers Over/Under

• Cardinals versus Brewers, on April 27, has an over/under of 8, with the over being -110 and the under -110.

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Cardinals vs Brewers Betting Trends

• The Cardinals have been favorites in eight games this season and have come away with the win four times (50%) in those contests.
• St. Louis has a record of 4-4 when favored by -110 or more this year.
• The Cardinals and their opponents have hit the over in 15 of their 27 games with a total set by oddsmakers this season.
• The Cardinals are 12-15-0 against the spread in their 27 games with a line set by sportsbooks this season.
• The Brewers have gone 3-11 in games they were listed as the moneyline underdog (winning 21.4% of those games).
• Milwaukee is 3-11 (winning only 21.4% of its games) when it has played as a moneyline underdog of -106 or longer.
• The Brewers have played in 28 games with a set over/under, and have combined with opponents to go over the total 12 times (12-16-0).
• The Brewers have covered 57.1% of their games this season, going 16-12-0 ATS.

Cardinals Player Leaders

• Lars Nootbaar is hitting .263 with four doubles, four home runs and 22 walks. He has an on-base percentage of .402 and a slugging percentage of .424.
• Among qualified hitters, he is 63rd in batting average, his on-base percentage ranks 14th, and he is 67th in slugging.
• Nootbaar has picked up at least one hit in two straight games. In his last five games he is hitting .300 with a double, a home run, five walks and six RBI.
• Brendan Donovan leads St. Louis with 36 hits and an OBP of .406, plus a team-best slugging percentage of .541. He's batting .367.
• Among qualifying batters, he is second in batting average, 12th in on-base percentage and 21st in slugging percentage.
• Donovan heads into this game looking to extend his four-game hit streak. In his last five games he is batting .316 with two doubles, two walks and two RBI.
• Nolan James Arenado has 25 hits this season and has a slash line of .266/.367/.447.
• Arenado enters this game with three games in a row with at least one hit. In his last five games he is batting .190 with two doubles, a home run, two walks and two RBI.
• Victor Scott II has one home run, 10 RBI and a batting average of .264 this season.

Brewers Player Leaders

• Jackson Chourio is leading the Brewers with 33 hits. He's batting .280 and slugging .534 with an on-base percentage of .295.
• Including all qualified players, he is 40th in batting average, while his on-base percentage is 108th and he is 23rd in slugging.
• Brice Turang is slugging .420 to pace his team. He has a batting average of .321 with an on-base percentage of .366.
• Including all qualified hitters, he is 13th in batting average, 36th in on-base percentage and 71st in slugging percentage.
• Christian Yelich is hitting .227 with three doubles, five home runs and 15 walks.
• Sal Frelick is batting .303 with four doubles, two triples, a home run and 11 walks.

Cardinals vs Brewers Head to Head

• 4/26/2025: 6-5 STL (Favorite: Cardinals, Spread: -1.5, Total: 7, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/25/2025: 3-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/4/2024: 3-2 STL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 9/3/2024: 7-4 STL (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 9/2/2024: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 8/22/2024: 3-0 STL (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 8/21/2024: 10-6 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/20/2024: 3-2 MIL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/12/2024: 4-3 STL (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 5/11/2024: 5-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)

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