Cardinals vs Brewers Prediction, Odds, Moneyline, Spread & Over/Under for April 25

Odds updated as of 8:11 p.m.

The MLB's Friday schedule includes the St. Louis Cardinals facing the Milwaukee Brewers.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information regarding this game.

Cardinals vs Brewers Game Info

• St. Louis Cardinals (10-15) vs. Milwaukee Brewers (13-13)
• Date: Friday, April 25, 2025
• Time: 8:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: FDSMW and FDSWI

Cardinals vs Brewers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-162) | MIL: (+136)
• Spread: STL: -1.5 (+130) | MIL: +1.5 (-156)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Cardinals vs Brewers Probable Starting Pitchers

Probable Pitchers: Matthew Liberatore (Cardinals) - 1-2, 3.60 ERA vs Chad Patrick (Brewers) - 1-1, 2.11 ERA

The Cardinals will look to Matthew Liberatore (1-2) versus the Brewers and Chad Patrick (1-1). Liberatore and his team have a record of 1-3-0 against the spread when he starts. Liberatore's team is 0-2 this season when he starts and they're favored on the moneyline. The Brewers have gone 3-1-0 ATS in Patrick's four starts that had a set spread. The Brewers were named the moneyline underdog for one Patrick start this season -- they lost.

Cardinals vs Brewers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (52.9%)

Cardinals vs Brewers Moneyline

• Milwaukee is a +136 underdog on the moneyline, while St. Louis is a -162 favorite at home.

Cardinals vs Brewers Spread

• The Brewers are +1.5 on the spread (-156 to cover), and St. Louis is +130 to cover the runline.

Cardinals vs Brewers Over/Under

• Cardinals versus Brewers on April 25 has an over/under of 7.5 runs, with the odds on the over -110 and the under set at -110.

Bet on St. Louis Cardinals vs. Milwaukee Brewers on FanDuel today!

Cardinals vs Brewers Betting Trends

• The Cardinals have been favorites in six games this season and have come away with the win two times (33.3%) in those contests.
• Oddsmakers have given St. Louis the best odds of winning it has seen this season, with a -162 moneyline listed for this contest.
• The Cardinals and their opponents have gone over the total this season in 14 of their 25 opportunities.
• The Cardinals have posted a record of 12-13-0 against the spread this season.
• The Brewers have put together a 3-9 record in games they were the underdog on the moneyline (winning 25% of those games).
• Milwaukee has played in three games as a moneyline underdog with odds of +136 or longer without winning.
• The Brewers have played in 26 games with a set over/under, and have combined with their opponents to go over the total 11 times (11-15-0).
• The Brewers have a 14-12-0 record against the spread this season.

Cardinals Player Leaders

• Brendan Donovan leads St. Louis with 32 hits and an OBP of .392, plus a team-best slugging percentage of .533. He's batting .356.
• Among qualifying batters in the majors, he is fourth in batting average, 25th in on-base percentage, and 24th in slugging.
• Donovan will look for his third straight game with a hit in this matchup. In his last five games he is hitting .263 with a double, a home run, a walk and two RBI.
• Lars Nootbaar is hitting .239 with three doubles, four home runs and 20 walks. He's slugging .402 with an on-base percentage of .381.
• Among all qualifying players, he is 88th in batting average, 31st in on-base percentage and 81st in slugging percentage.
• Nolan James Arenado is batting .267 with a .430 slugging percentage and 11 RBI this year.
• Victor Scott II is batting .275 with a .337 OBP and 10 RBI for St. Louis this season.

Brewers Player Leaders

• Brice Turang has accumulated a team-high .452 slugging percentage. He's batting .346 with an on-base percentage of .386.
• He ranks fifth in batting average, 28th in on-base percentage and 56th in slugging percentage among all qualifying hitters in MLB.
• Turang brings a three-game hitting streak into this matchup. During his last five outings he is hitting .500 with a double, three walks and four RBI.
• Jackson Chourio has racked up 27 hits to pace his team. He has a batting average of .248 while slugging .477 with an on-base percentage of .265.
• His batting average ranks 81st among all qualified players, his on-base percentage is 137th, and he is 40th in slugging.
• Christian Yelich is batting .216 with three doubles, five home runs and 15 walks.
• Sal Frelick leads his team with a .396 on-base percentage.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!