Brewers vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for May 22

Odds updated as of 4:11 a.m.

MLB action on Thursday includes the Milwaukee Brewers playing the Pittsburgh Pirates.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this game.

Brewers vs Pirates Game Info

• Milwaukee Brewers (24-26) vs. Pittsburgh Pirates (17-33)
• Date: Thursday, May 22, 2025
• Time: 6:40 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and FDSWI

Brewers vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-120) | PIT: (+102)
• Spread: MIL: -1.5 (+126) | PIT: +1.5 (-152)
• Total: 9 -- Over: (-112) | Under: (-108)

Brewers vs Pirates Probable Starting Pitchers

Probable Pitchers: TBA (Brewers) vs Mike Burrows (Pirates) - 0-0, 0.00 ERA

Burrows will get the nod for the Pirates. As of this writing, there's been no pitching decision announced by the Brewers. Burrows' team was never a moneyline underdog a season ago in games he pitched.

Brewers vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (50.5%)

Brewers vs Pirates Moneyline

• Milwaukee is a -120 favorite on the moneyline, while Pittsburgh is a +102 underdog at home.

Brewers vs Pirates Spread

• The Pirates are at +1.5 on the runline against the Brewers. The Pirates are -152 to cover the spread, and the Brewers are +126.

Brewers vs Pirates Over/Under

• Brewers versus Pirates, on May 22, has an over/under of 9, with the over being -112 and the under -108.

Bet on Milwaukee Brewers vs. Pittsburgh Pirates on FanDuel today!

Brewers vs Pirates Betting Trends

• The Brewers have been favorites in 25 games this season and have come away with the win 17 times (68%) in those contests.
• This season Milwaukee has come away with a win 13 times in 18 chances when named as a favorite of at least -120 on the moneyline.
• The Brewers and their opponents have gone over the total this season in 19 of their 49 opportunities.
• In 49 games with a line this season, the Brewers have a mark of 26-23-0 against the spread.
• The Pirates are 12-21 in games they were listed as the moneyline underdog (winning 36.4% of those games).
• Pittsburgh has gone 10-19 when it has played as a moneyline underdog with odds of +102 or longer (34.5%).
• The Pirates have played in 48 games with a set over/under, and have combined with their opponents to go over the total 17 times (17-28-3).
• The Pirates have collected a 20-28-0 record ATS this season (covering 41.7% of the time).

Brewers Player Leaders

• Brice Turang leads Milwaukee in slugging percentage (.379) thanks to eight extra-base hits. He has a .288 batting average and an on-base percentage of .363.
• Among all qualified batters in MLB, his batting average ranks 30th, his on-base percentage ranks 39th, and he is 112th in slugging.
• William Contreras is batting .255 with six doubles, four home runs and 31 walks. He's slugging .366 with an on-base percentage of .373.
• Among qualified batters, his batting average places him 81st, his on-base percentage 30th, and his slugging percentage 122nd.
• Rhys Hoskins leads his team in OBP (.402) and total hits (45) this season.
• Hoskins takes a five-game hitting streak into this game. In his last five games he is hitting .412 with two doubles, two home runs, three walks and three RBIs.
• Jackson Chourio leads Milwaukee in slugging percentage (.415) thanks to 22 extra-base hits.
• Chourio takes a two-game hitting streak into this game. In his last five games he is hitting .136 with a walk and an RBI.

Pirates Player Leaders

• Oneil Cruz has accumulated a team-high OBP (.350), and paces the Pirates in hits (32). He's batting .221 and slugging.
• Including all qualifying hitters, he is 134th in batting average, while his on-base percentage is 56th and he is 77th in slugging.
• Andrew McCutchen has seven doubles, three home runs and 20 walks while hitting .243. He's slugging .357 with an on-base percentage of .344.
• His batting average ranks 95th among all qualified players, his on-base percentage ranks 60th, and he is 132nd in slugging.
• Bryan Reynolds is batting .203 with five doubles, six home runs and 17 walks.
• Ke'Bryan Hayes' .310 slugging percentage leads his team.

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