Astros vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for April 15

Odds updated as of 4:12 a.m.

The Houston Astros will take on the Colorado Rockies in MLB action on Wednesday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information regarding this game.

Astros vs Rockies Game Info

• Houston Astros (7-11) vs. Colorado Rockies (6-11)
• Date: Wednesday, April 15, 2026
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and Rockies.TV

Astros vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-184) | COL: (+154)
• Spread: HOU: -1.5 (+118) | COL: +1.5 (-142)
• Total: 8.5 -- Over: (-115) | Under: (-105)

Astros vs Rockies Probable Starting Pitchers

Probable Pitchers: Spencer Arrighetti (Astros) - 0-0, 0.00 ERA vs José Quintana (Rockies) - 0-0, 4.15 ERA

This contest's pitching matchup is set, as the Astros will send Spencer Arrighetti to the mound, while Jose Quintana will take the ball for the Rockies. Arrighetti did not pitch as the moneyline favorite in any games last season. Quintana has started only one game with a set spread, which the Rockies covered. The Rockies were named the moneyline underdog for one Quintana start this season -- they lost.

Astros vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (69.9%)

Astros vs Rockies Moneyline

• Houston is the favorite, -184 on the moneyline, while Colorado is a +154 underdog on the road.

Astros vs Rockies Spread

• The Rockies are +1.5 on the run line against the Astros. The Rockies are -142 to cover, and the Astros are +118.

Astros vs Rockies Over/Under

• An over/under of 8.5 has been set for Astros-Rockies on April 15, with the over being -115 and the under -105.

Bet on Houston Astros vs. Colorado Rockies on FanDuel today!

Astros vs Rockies Betting Trends

• The Astros have been victorious in four of the 10 contests they have been chosen as favorites in this season.
• Houston has played as a favorite of -184 or more just one time this year and came away with a loss in that game.
• The Astros and their opponents have gone over in 13 of their 18 games with a total set by sportsbooks this season.
• The Astros are 7-11-0 against the spread in their 18 games that had a posted line this season.
• The Rockies have won six of the 17 games they were the moneyline underdog this season (35.3%).
• In games it has played as a moneyline underdog with odds of +154 or longer, Colorado has a record of 2-8 (20%).
• The Rockies have played in 17 games with an over/under set, and have combined with opponents to go over the total seven times (7-10-0).
• The Rockies are 11-6-0 ATS this season.

Astros Player Leaders

• Yordan Alvarez leads Houston in OBP (.475) and total hits (19) this season. He's batting .317 batting average while slugging .700.
• Among qualified hitters in MLB, his batting average ranks 18th, his on-base percentage ranks second, and he is third in slugging.
• Christian Walker has hit four homers this season while driving in 15 runs. He's batting .313 this season and slugging .594 with an on-base percentage of .389.
• He is 24th in batting average, 29th in on-base percentage and 11th in slugging among qualifying hitters.
• Jose Altuve is batting .288 with a .455 slugging percentage and six RBI this year.
• Cam Smith has been key for Houston with 18 hits, an OBP of .361 plus a slugging percentage of .484.
• Smith takes a two-game hitting streak into this matchup. In his last five games he is batting .300 with two doubles and three RBIs.

Rockies Player Leaders

• T.J. Rumfield has put up an on-base percentage of .365 and a slugging percentage of .464. Both lead the Rockies. He's batting .304.
• Including all the qualified hitters in MLB, his batting average is 30th, his on-base percentage ranks 49th, and he is 58th in slugging.
• Mickey Moniak is batting .243 with five home runs and a walk. He's slugging .649 with an on-base percentage of .256.
• Troy Johnston is hitting .298 with three doubles, two home runs and three walks.
• Hunter Goodman's 15 hits lead his team.

Astros vs Rockies Head to Head

• 4/14/2026: 7-6 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 4/8/2026: 9-1 COL (Favorite: Astros, Spread: -1.5, Total: 11, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/7/2026: 5-1 COL (Favorite: Astros, Spread: -1.5, Total: 11, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 4/6/2026: 9-7 COL (Favorite: Astros, Spread: -1.5, Total: 10.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/28/2025: 4-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 8/27/2025: 4-0 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -275, Underdog Moneyline: +225)
• 8/26/2025: 6-1 COL (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -375, Underdog Moneyline: +300)
• 7/3/2025: 7-6 COL (Favorite: Astros, Spread: -1.5, Total: 11, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 7/2/2025: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 11, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 7/1/2025: 6-5 HOU (Favorite: Astros, Spread: -1.5, Total: 11.5, Favorite Moneyline: -152, Underdog Moneyline: +128)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!