Yankees vs Diamondbacks Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 18

Odds updated as of 4:12 a.m.

In MLB action on Friday, the New York Yankees take on the Arizona Diamondbacks.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Yankees vs Diamondbacks Game Info

• New York Yankees (88-64) vs. Arizona Diamondbacks (80-73)
• Date: Friday, September 18, 2026
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: Dbacks.TV and YES

Yankees vs Diamondbacks Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-126) | ARI: (+108)
• Spread: NYY: -1.5 (+132) | ARI: +1.5 (-160)
• Total: 8.5 -- Over: (-104) | Under: (-118)

Yankees vs Diamondbacks Probable Starting Pitchers

Probable Pitchers: Gerrit Cole (Yankees) - 8-9, 3.67 ERA vs Eduardo Rodríguez (Diamondbacks) - 15-6, 2.62 ERA

The Yankees will give the ball to Gerrit Cole (8-9, 3.67 ERA), who is eyeing win No. 9 on the season, and the Diamondbacks will turn to Eduardo Rodriguez (15-6, 2.62 ERA). Cole and his team are 7-13-0 ATS this season when he starts. Cole's team has been victorious in 50% of the games he's started as the moneyline favorite with a record of 8-8. The Diamondbacks are 18-12-0 ATS in Rodríguez's 30 starts with a set spread. The Diamondbacks are 13-4 in Rodríguez's 17 starts this season that they were the underdog on the moneyline.

Yankees vs Diamondbacks Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (56.3%)

Yankees vs Diamondbacks Moneyline

• The moneyline numbers for Yankees vs. Diamondbacks reveal New York as the favorite (-126) and Arizona as the underdog (+108) despite being the home team.

Yankees vs Diamondbacks Spread

• The Yankees are at the Diamondbacks and are favored by 1.5 runs (+132 to cover) on the runline. Arizona is -160 to cover.

Yankees vs Diamondbacks Over/Under

• The Yankees-Diamondbacks game on Sept. 18 has been given an over/under of 8.5 runs. The over is set at -104 and the under at -118.

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Yankees vs Diamondbacks Betting Trends

• The Yankees have won in 71, or 60.2%, of the 118 contests they have been named as odds-on favorites in this year.
• New York has a record of 58-36 when favored by -126 or more this year.
• The Yankees and their opponents have hit the over in 67 of their 147 games with a total set by oddsmakers this season.
• The Yankees are 76-71-0 against the spread in their 147 games that had a posted line this season.
• The Diamondbacks have a 38-43 record in games they were the underdog on the moneyline (winning 46.9% of those games).
• Arizona is 26-32 (winning 44.8% of its games) when playing as a moneyline underdog of +108 or longer.
• In the 151 games bookmakers have set an over/under for the Diamondbacks, they have combined with opponents to go over the total 64 times (64-83-4).
• The Diamondbacks are 78-73-0 ATS this season.

Yankees Player Leaders

• Ben Rice leads New York with an OBP of .360, plus a team-best slugging percentage of .524. He's batting .262 on the season.
• Among all qualified hitters in MLB, his batting average ranks 59th, his on-base percentage ranks 30th, and he is seventh in slugging.
• Rice will look for his seventh straight game with a hit in this contest. During his last 10 outings he is hitting .333 with two home runs, 10 walks and four RBIs.
• Luis Garcia leads New York with 140 hits. He is batting .283 this season and has 61 extra-base hits. He's also slugging .538 with an on-base percentage of .314.
• Among qualifiers, he ranks 19th in batting average, 100th in on-base percentage and third in slugging percentage.
• Cody Bellinger has collected 129 base hits, an OBP of .351 and a slugging percentage of .444 this season.
• Bellinger heads into this matchup with three games in a row with at least one hit. In his last five games he is hitting .429 with two home runs, two walks and four RBIs.
• Jose Caballero is batting .234 with a .290 OBP and 51 RBI for New York this season.

Diamondbacks Player Leaders

• Corbin Carroll has 30 doubles, 16 triples, 21 home runs and 70 walks while batting .238. He's slugging .465 with an on-base percentage of .330.
• Including all the qualified hitters in the big leagues, his batting average is 102nd, his on-base percentage ranks 69th, and he is 35th in slugging.
• Ketel Marte has 29 doubles, three triples, 22 home runs and 47 walks while hitting .250. He's slugging .442 with an on-base percentage of .316.
• His batting average is 77th among all qualified players, his on-base percentage is 93rd, and he is 54th in slugging.
• Gabriel Moreno has put up an on-base percentage of .385, a slugging percentage of .485, and has 136 hits, all club-highs for the Diamondbacks.
• Geraldo Perdomo is batting .252 with 19 doubles, six triples, nine home runs and 89 walks.

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