Padres vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 18

Odds updated as of 9:11 p.m.

Friday's slate in the MLB includes a matchup between the San Diego Padres and the Miami Marlins.

All the information you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Padres vs Marlins Game Info

• San Diego Padres (84-69) vs. Miami Marlins (76-77)
• Date: Friday, September 18, 2026
• Time: 9:40 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and Marlins.TV

Padres vs Marlins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-205) | MIA: (+172)
• Spread: SD: -1.5 (+104) | MIA: +1.5 (-125)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Padres vs Marlins Probable Starting Pitchers

Probable Pitchers: Nick Pivetta (Padres) - 2-2, 3.60 ERA vs Tyler Phillips (Marlins) - 5-6, 3.55 ERA

The Padres will give the nod to Nick Pivetta (2-2, 3.60 ERA), who is eyeing win No. 3 on the season, and the Marlins will counter with Tyler Phillips (5-6, 3.55 ERA). Pivetta and his team have a record of 3-3-0 against the spread when he starts. Pivetta and his team have won each of the four games he's started as the moneyline favorite. The Marlins are 10-8-0 ATS in Phillips' 18 starts with a set spread. The Marlins have a 7-6 record in Phillips' 13 starts this season when they were the moneyline underdog.

Padres vs Marlins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (56.2%)

Padres vs Marlins Moneyline

• Looking at the moneyline for Marlins-Padres, Miami is the underdog at +172, and San Diego is -205 playing at home.

Padres vs Marlins Spread

• The Padres are 1.5-run home favorites on the runline against the Marlins. The Padres are +104 to cover, and the Marlins are -125.

Padres vs Marlins Over/Under

• An over/under of 7.5 has been set for Padres-Marlins on Sept. 18, with the over being -110 and the under -110.

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Padres vs Marlins Betting Trends

• The Padres have come away with 45 wins in the 75 contests they have been listed as the favorites in this season.
• San Diego has been a -205 moneyline favorite on three occasions this season and won every time.
• The Padres and their opponents have gone over in 71 of their 153 games with a total set by sportsbooks this season.
• The Padres are 88-65-0 against the spread in their 153 games that had a posted line this season.
• The Marlins have gone 35-50 in games they were listed as the moneyline underdog (winning 41.2% of those games).
• Miami has a record of 2-3 when playing as a moneyline underdog with odds of +172 or longer (40%).
• The Marlins have played in 151 games with a set over/under, and have combined with opponents to go over the total 76 times (76-73-2).
• The Marlins have covered 51.7% of their games this season, going 78-73-0 ATS.

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego in OBP (.355), slugging percentage (.462) and total hits (170) this season. He has a .286 batting average.
• Among all qualifying hitters in MLB, he is 13th in batting average, 36th in on-base percentage, and 37th in slugging.
• Jackson Merrill is batting .256 with 25 doubles, five triples, 25 home runs and 39 walks, while slugging .444 with an on-base percentage of .304.
• He is 69th in batting average, 113th in on-base percentage and 50th in slugging in the majors.
• Merrill takes an eight-game streak with at least one hit into this contest. During his last 10 games he is batting .488 with three doubles, two triples, three home runs, a walk and 15 RBIs.
• Manny Machado has 122 hits this season and has a slash line of .220/.309/.412.
• Xander Bogaerts has been key for San Diego with 113 hits, an OBP of .325 plus a slugging percentage of .336.

Marlins Player Leaders

• Otto Lopez has a .439 slugging percentage, which leads the Marlins. He's batting .306 with an on-base percentage of .348.
• He is fifth in batting average, 46th in on-base percentage and 58th in slugging percentage among all qualified hitters in MLB.
• Xavier Edwards' .361 on-base percentage leads his team. He has a batting average of .282 while slugging .374.
• He is 20th in batting average, 27th in on-base percentage and 114th in slugging percentage in the majors.
• Javier Sanoja is hitting .292 with 30 doubles, five triples, nine home runs and 25 walks.
• Jakob Marsee is batting .227 with 19 doubles, six triples, 11 home runs and 74 walks.

Padres vs Marlins Head to Head

• 7/26/2026: 5-3 SD (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/25/2026: 7-2 SD (Favorite: Marlins, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/24/2026: 4-2 SD (Favorite: Marlins, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/23/2025: 3-2 MIA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 7/22/2025: 4-3 MIA (Favorite: Marlins, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/21/2025: 2-1 SD (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/28/2025: 10-8 MIA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/27/2025: 8-6 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/26/2025: 4-3 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/11/2024: 7-6 MIA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -200, Underdog Moneyline: +168)

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