Twins vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 18

Odds updated as of 4:12 a.m.

MLB action on Friday includes the Minnesota Twins playing the Los Angeles Angels.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this game.

Twins vs Angels Game Info

• Minnesota Twins (71-82) vs. Los Angeles Angels (59-94)
• Date: Friday, September 18, 2026
• Time: 9:38 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: ABTV and Twins.TV

Twins vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-126) | LAA: (+108)
• Spread: MIN: -1.5 (+132) | LAA: +1.5 (-160)
• Total: 8.5 -- Over: (-102) | Under: (-120)

Twins vs Angels Probable Starting Pitchers

Probable Pitchers: Connor Prielipp (Twins) - 5-7, 5.24 ERA vs Grayson Rodriguez (Angels) - 4-7, 6.10 ERA

The Twins will give the nod to Connor Prielipp (5-7) against the Angels and Grayson Rodriguez (4-7). Prielipp and his team are 11-9-0 ATS this season when he starts. When Prielipp starts a game and his team is the favorite on the moneyline, they have a record of 3-1. The Angels are 9-9-0 ATS in Rodriguez's 18 starts that had a set spread. The Angels have a 4-13 record in Rodriguez's 17 starts this season when they were the moneyline underdog.

Twins vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (55%)

Twins vs Angels Moneyline

• The moneyline numbers for Twins vs. Angels reveal Minnesota as the favorite (-126) and Los Angeles as the underdog (+108) despite being the home team.

Twins vs Angels Spread

• The Angels are hosting the Twins, and are +1.5 on the runline. The Angels are +132 to cover the spread, and the Twins are -160.

Twins vs Angels Over/Under

• Twins versus Angels, on Sept. 18, has an over/under of 8.5, with the over being -102 and the under -120.

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Twins vs Angels Betting Trends

• The Twins have won in 28, or 51.9%, of the 54 contests they have been named as odds-on favorites in this year.
• This season Minnesota has come away with a win 12 times in 26 chances when named as a favorite of at least -126 on the moneyline.
• Contests with the Twins have gone over the total set by bookmakers in 85 of 149 chances this season.
• The Twins have posted a record of 79-70-0 against the spread this season.
• The Angels are 44-80 in games they were the underdog on the moneyline (winning 35.5% of those games).
• Los Angeles is 37-65 (winning only 36.3% of its games) when it has played as a moneyline underdog of +108 or longer.
• The Angels have played in 152 games with an over/under set, and have combined with their opponents to go over the total 63 times (63-86-3).
• The Angels have gone 81-71-0 ATS this season.

Twins Player Leaders

• Brooks Lee is batting .248 with 23 doubles, three triples, 23 home runs and 36 walks. He has an on-base percentage of .298 while slugging .427.
• Among qualified batters in baseball, he ranks 82nd in batting average, 120th in on-base percentage, and 66th in slugging.
• Lee will look for his third straight game with a hit in this contest. In his last five games he is hitting .235 with two walks and two RBIs.
• Josh Bell is batting .252 with 28 doubles, a triple, 20 home runs and 48 walks. He's slugging .419 with an on-base percentage of .315.
• His batting average is 72nd among qualified players, his on-base percentage 97th, and his slugging percentage 74th.
• Bell heads into this game looking to extend his two-game hit streak. During his last five outings he is hitting .190 with a home run, a walk and two RBIs.
• Kody Clemens leads Minnesota in total hits (120) this season, and 55 of those have gone for extra bases.
• Clemens takes a three-game hitting streak into this matchup. In his last five games he is batting .211 with a double, a triple, three walks and an RBI.
• Luke Keaschall leads the Twins with an OPS of .757. He has a slash line of .279/.370/.387 this season.
• Keaschall takes a three-game hitting streak into this game. In his last five games he is batting .450 with three walks and an RBI.

Angels Player Leaders

• Zach Neto has accumulated a team-best slugging percentage (.440) while leading the Angels in hits (142). He's batting .241 and with an on-base percentage of .323.
• Including all qualified hitters in MLB, he is 95th in batting average, 81st in on-base percentage and 56th in slugging percentage.
• Mike Trout's .379 on-base percentage paces his team. He has a batting average of .241 while slugging .423.
• Including all qualifying hitters, he is 95th in batting average, ninth in on-base percentage and 71st in slugging percentage.
• Vaughn Grissom is hitting .238 with 22 doubles, 11 home runs and 28 walks.
• Wade Meckler is batting .294 with 14 doubles, three home runs and 30 walks.

Twins vs Angels Head to Head

• 9/17/2026: 5-4 LAA (Favorite: Angels, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 7/12/2026: 4-2 MIN (Favorite: Twins, Spread: -1.5, Total: 9.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/11/2026: 5-3 MIN (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 7/10/2026: 4-3 LAA (Favorite: Twins, Spread: -1.5, Total: 9.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 9/10/2025: 4-3 LAA (Favorite: Angels, Spread: -1.5, Total: 9.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/9/2025: 12-2 LAA (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/8/2025: 12-3 MIN (Favorite: Angels, Spread: -1.5, Total: 9.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/27/2025: 5-0 MIN (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 4/26/2025: 5-1 MIN (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/25/2025: 11-4 MIN (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -205, Underdog Moneyline: +172)

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