White Sox vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 26

Odds updated as of 6:13 p.m.

The Saturday slate in MLB includes a matchup between the Chicago White Sox and the Colorado Rockies.

We've got you covered, in terms of the most important information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

White Sox vs Rockies Game Info

• Chicago White Sox (83-77) vs. Colorado Rockies (57-103)
• Date: Saturday, September 26, 2026
• Time: 7:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and Rockies.TV

White Sox vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-260) | COL: (+215)
• Spread: CHW: -1.5 (-120) | COL: +1.5 (+100)
• Total: 8.5 -- Over: (+104) | Under: (-128)

White Sox vs Rockies Probable Starting Pitchers

Probable Pitchers: Davis Martin (White Sox) - 9-7, 3.84 ERA vs José Quintana (Rockies) - 2-3, 5.40 ERA

This contest's pitching matchup is set, as the White Sox will send Davis Martin (9-7) to the mound, while Jose Quintana (2-3) will get the nod for the Rockies. When Martin starts, his team is 14-13-0 against the spread this season. Martin's team has a record of 4-4 this season when he starts and they are the favorite on the moneyline. The Rockies have gone 6-4-0 against the spread when Quintana starts. The Rockies are 5-5 in Quintana's 10 starts this season that they were the underdog on the moneyline.

White Sox vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: White Sox win (68.9%)

White Sox vs Rockies Moneyline

• Looking at the moneyline for Rockies-White Sox, Colorado is the underdog at +215, and Chicago is -260 playing at home.

White Sox vs Rockies Spread

• The Rockies are at the White Sox, and are +1.5 on the runline. The Rockies are -120 to cover the spread, and the White Sox are +100.

White Sox vs Rockies Over/Under

• The over/under for White Sox-Rockies on Sept. 26 is 8.5. The over is +104, and the under is -128.

Bet on Chicago White Sox vs. Colorado Rockies on FanDuel today!

White Sox vs Rockies Betting Trends

• The White Sox have been favorites in 44 games this season and have come away with the win 25 times (56.8%) in those contests.
• Oddsmakers have given Chicago the best odds of winning it has seen this season, with a -260 moneyline listed for this contest.
• Contests with the White Sox have gone over the total set by bookmakers in 88 of 157 chances this season.
• In 157 games with a line this season, the White Sox have a mark of 89-68-0 against the spread.
• The Rockies have been the moneyline underdog 153 total times this season. They've finished 54-99 in those games.
• When it has played as a moneyline underdog with odds of +215 or longer, Colorado has a 5-11 record (winning just 31.2% of its games).
• The Rockies have played in 157 games with a set over/under, and have combined with opponents to go over the total 76 times (76-78-3).
• The Rockies have an 81-76-0 record ATS this season.

White Sox Player Leaders

• Miguel Vargas has 31 doubles, a triple, 33 home runs and 98 walks while batting .251. He has an on-base percentage of .361 and a slugging percentage of .476.
• He ranks 75th in batting average, 28th in on-base percentage, and 29th in slugging among all qualified batters in the majors.
• Chase Meidroth has an OPS of .763, fueled by an OBP of .350 and a team-best slugging percentage of .413 this season. He's batting .275.
• Among all qualified, he ranks 34th in batting average, 43rd in on-base percentage and 80th in slugging percentage.
• Meidroth has picked up at least one hit in four straight games. In his last five games he is batting .444 with a double, two home runs, a walk and seven RBIs.
• Sam Antonacci leads Chicago in OBP (.368) this season, fueled by 130 hits.
• Antonacci has recorded at least one base hit in four games in a row. In his last five games he is hitting .400 with a double, a walk and three RBIs.
• Munetaka Murakami leads Chicago in total hits (93) this season while batting .209 with 51 extra-base hits.
• Murakami takes a four-game hitting streak into this game. In his last five games he is hitting .353 with a double, three home runs, four walks and eight RBIs.

Rockies Player Leaders

• Jake McCarthy is hitting .293 with 30 doubles, 13 triples, 15 home runs and 29 walks. He's slugging .480 with an on-base percentage of .335.
• He ranks eighth in batting average, 59th in on-base percentage and 27th in slugging percentage among all qualified hitters in the big leagues.
• TJ Rumfield has a .389 on-base percentage while slugging .452. Both lead his team. He has a batting average of .299.
• He ranks seventh in batting average, third in on-base percentage and 42nd in slugging percentage in MLB.
• Hunter Goodman has totaled 125 hits, a team-best for the Rockies.
• Kyle Karros is batting .256 with 21 doubles, three triples, 13 home runs and 54 walks.

White Sox vs Rockies Head to Head

• 9/25/2026: 6-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 7/6/2025: 6-4 COL (Favorite: White Sox, Spread: -1.5, Total: 11, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/5/2025: 10-3 CHW (Favorite: Rockies, Spread: -1.5, Total: 11, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/4/2025: 3-2 CHW (Favorite: White Sox, Spread: -1.5, Total: 11, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/30/2024: 5-4 COL (Favorite: White Sox, Spread: -1.5, Total: 7, Favorite Moneyline: -230, Underdog Moneyline: +190)
• 6/29/2024: 11-3 CHW (Favorite: White Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/20/2023: 10-5 CHW (Favorite: White Sox, Spread: -1.5, Total: 11.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/19/2023: 11-5 COL (Favorite: White Sox, Spread: -1.5, Total: 11.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/18/2023: 14-1 COL (Favorite: Rockies, Spread: -1.5, Total: 12, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/14/2022: 3-0 COL (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -275, Underdog Moneyline: +225)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!