Dodgers vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 26

Odds updated as of 12:11 a.m.

The MLB slate on Saturday includes the Los Angeles Dodgers facing the San Francisco Giants.

We've got you covered, in terms of the most important info regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Dodgers vs Giants Game Info

• Los Angeles Dodgers (97-62) vs. San Francisco Giants (65-94)
• Date: Saturday, September 26, 2026
• Time: 4:05 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and SportsNet LA

Dodgers vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-335) | SF: (+270)
• Spread: LAD: -1.5 (-176) | SF: +1.5 (+146)
• Total: 7.5 -- Over: (+106) | Under: (-130)

Dodgers vs Giants Probable Starting Pitchers

Probable Pitchers: Blake Snell (Dodgers) - 4-1, 1.86 ERA vs Matt Wilkinson (Giants) - 1-3, 3.65 ERA

The Dodgers will call on Blake Snell (4-1) versus the Giants and Matt Wilkinson (1-3). Snell's team is 4-4-0 against the spread in his starts this season. When Snell starts a game and his team is the favorite on the moneyline, they have a record of 5-3. The Giants are 2-3-0 ATS in Wilkinson's five starts that had a set spread. The Giants have been the moneyline underdog in five of Wilkinson's starts this season, and they went 1-4 in those matchups.

Dodgers vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (57.7%)

Dodgers vs Giants Moneyline

• Los Angeles is the favorite, -335 on the moneyline, while San Francisco is a +270 underdog despite being at home.

Dodgers vs Giants Spread

• The Giants are at +1.5 on the runline against the Dodgers. The Giants are +146 to cover the spread, and the Dodgers are -176.

Dodgers vs Giants Over/Under

• A total of 7.5 runs has been set for the Dodgers-Giants contest on Sept. 26, with the over available at +106 and the under at -130.

Bet on Los Angeles Dodgers vs. San Francisco Giants on FanDuel today!

Dodgers vs Giants Betting Trends

• The Dodgers have been favorites in 151 games this season and have come away with the win 94 times (62.3%) in those contests.
• Los Angeles has been a -335 moneyline favorite on three occasions this season and won every time.
• The Dodgers and their opponents have gone over in 73 of their 157 games with a total set by sportsbooks this season.
• The Dodgers have posted a record of 66-91-0 against the spread this season.
• The Giants have put together a 40-70 record in games they were listed as the moneyline underdog (winning 36.4% of those games).
• San Francisco has played as a moneyline underdog of +270 or longer in only one game this season, which it lost.
• The Giants have combined with opponents to go over the total 76 times this season for a 76-70-10 record against the over/under.
• The Giants have gone 75-81-0 ATS this season.

Dodgers Player Leaders

• Shohei Ohtani leads Los Angeles in OBP (.381) and total hits (142) this season. He's batting .278 batting average while slugging .521.
• Among qualifying batters in baseball, he ranks 27th in batting average, ninth in on-base percentage, and seventh in slugging.
• Ohtani hopes to build on a two-game hitting streak in this matchup. During his last five outings he is batting .222 with a double, four walks and an RBI.
• Freddie Freeman has an OPS of .801, fueled by an OBP of .366 and a team-best slugging percentage of .435 this season. He's batting .292.
• Among qualifying batters, he is ninth in batting average, 20th in on-base percentage and 58th in slugging percentage.
• Kyle Tucker has 124 hits this season and has a slash line of .235/.332/.390.
• Mookie Betts has 22 home runs, 68 RBI and a batting average of .261 this season.

Giants Player Leaders

• Drew Gilbert is batting .240 with 14 doubles, three triples, 11 home runs and 37 walks. He's slugging .398 with an on-base percentage of .329.
• Gilbert heads into this game on a three-game hitting streak. During his last five outings he is hitting .556 with a home run and three RBIs.
• Marcelo Mayer is hitting .213 with 10 doubles, three home runs and 18 walks. He's slugging .303 with an on-base percentage of .281.
• Christian Koss is hitting .228 with six doubles, four home runs and nine walks.
• Jonah Cox is hitting .266 with three doubles, two triples, four home runs and 10 walks.

Dodgers vs Giants Head to Head

• 9/20/2026: 3-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 9/19/2026: 10-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -450, Underdog Moneyline: +350)
• 9/18/2026: 8-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -320, Underdog Moneyline: +260)
• 5/14/2026: 5-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/13/2026: 4-0 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 5/12/2026: 6-2 SF (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -310, Underdog Moneyline: +250)
• 5/11/2026: 9-3 SF (Favorite: Dodgers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/23/2026: 3-0 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 4/22/2026: 3-0 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 4/21/2026: 3-1 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -186, Underdog Moneyline: +144)

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