Reds vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for April 21

Odds updated as of 6:11 p.m.

In MLB action on Monday, the Cincinnati Reds face the Miami Marlins.

We've got you covered, in terms of the most important info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Reds vs Marlins Game Info

• Cincinnati Reds (11-11) vs. Miami Marlins (9-12)
• Date: Monday, April 21, 2025
• Time: 6:40 p.m. ET
• Venue: loanDepot park -- Miami, Florida
• Coverage: FDSFL and FDSOH

Reds vs Marlins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-118) | MIA: (-100)
• Spread: CIN: -1.5 (+136) | MIA: +1.5 (-164)
• Total: 8 -- Over: (-105) | Under: (-115)

Reds vs Marlins Probable Starting Pitchers

Probable Pitchers: Nick Lodolo (Reds) - 2-1, 2.31 ERA vs Max Meyer (Marlins) - 1-2, 2.63 ERA

The probable pitchers are Nick Lodolo (2-1) for the Reds and Max Meyer (1-2) for the Marlins. Lodolo's team is 3-1-0 against the spread in his starts this season. Lodolo's team won his only start as a favorite this season. When Meyer starts, the Marlins have gone 2-2-0 against the spread. The Marlins have a 1-2 record in Meyer's three starts this season when they were the underdog on the moneyline.

Reds vs Marlins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (58.6%)

Reds vs Marlins Moneyline

• Cincinnati is the favorite, -118 on the moneyline, while Miami is a -100 underdog despite being at home.

Reds vs Marlins Spread

• The Marlins are +1.5 on the run line against the Reds. The Marlins are -164 to cover, and the Reds are +136.

Reds vs Marlins Over/Under

• The over/under for the Reds versus Marlins game on April 21 has been set at 8, with -105 odds on the over and -115 odds on the under.

Bet on Cincinnati Reds vs. Miami Marlins on FanDuel today!

Reds vs Marlins Betting Trends

• The Reds have been victorious in four of the six contests they have been chosen as favorites in this season.
• Cincinnati has a record of 4-2 when favored by -118 or more this year.
• The Reds and their opponents have gone over the total this season in 11 of their 22 opportunities.
• The Reds are 13-9-0 against the spread in their 22 games that had a posted line this season.
• The Marlins have a 7-12 record in games they were listed as the moneyline underdog (winning 36.8% of those games).
• When playing as a moneyline underdog with odds of -100 or longer, Miami has a 7-11 record (winning only 38.9% of its games).
• The Marlins have had an over/under set by bookmakers 21 times, and have combined with opponents to go over the total in 14 of those games (14-7-0).
• The Marlins have covered 52.4% of their games this season, going 11-10-0 against the spread.

Reds Player Leaders

• Elly De La Cruz has 21 hits, which ranks first among Cincinnati hitters this season, while batting .241 with eight extra-base hits. He has an on-base percentage of .313 and a slugging percentage of .448.
• He is 88th in batting average, 95th in on-base percentage, and 57th in slugging among qualifying hitters in the majors.
• De La Cruz has hit safely in five games in a row. During his last five outings he is hitting .300 with two home runs, four walks and four RBI.
• TJ Friedl has hit one homers this season while driving in 10 runs. He's batting .296 this season and slugging .395 with an on-base percentage of .363.
• Among qualified batters, his batting average ranks him 38th, his on-base percentage 46th, and his slugging percentage 92nd.
• Friedl has picked up a hit in four straight games. During his last five outings he is hitting .409 with a double, a triple, four walks and four RBI.
• Matt McLain is batting .204 with a .469 slugging percentage and 10 RBI this year.
• Gavin Lux has 22 hits this season and a team-best OBP of .427.
• Lux has hit safely in six straight games. In his last 10 outings he is batting .455 with three doubles, nine walks and six RBI.

Marlins Player Leaders

• Otto Lopez is hitting .234 with five doubles, two home runs and nine walks. He's slugging .377 with an on-base percentage of .314.
• Including all the qualified players in the majors, he ranks 92nd in batting average, 91st in on-base percentage and 102nd in slugging percentage.
• Xavier Edwards' .333 slugging percentage leads his team. He has a batting average of .299 with an on-base percentage of .380.
• Including all qualified players, he is 34th in batting average, 33rd in on-base percentage and 129th in slugging percentage.
• Eric Wagaman is batting .267 with four doubles, two home runs and six walks.
• Kyle Stowers has a .381 OBP to lead his team.

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