Rams vs 49ers Prediction, Odds, Picks, Best Bets for NFL Week 5 Thursday Night Football

The Los Angeles Rams will take on the San Francisco 49ers in NFL action on Thursday.
All the information you need is below, in order to make a smart wager on this matchup at FanDuel Sportsbook.
Rams vs 49ers Prediction & Pick
All NFL win probability predictions and picks are according to numberFire.
Prediction: Rams win (61.7%)
Rams vs 49ers Point Spread
The Rams are 8.5-point favorites against the 49ers. The Rams are -105 to cover the spread, while the 49ers are -115 to cover as an 8.5-point underdog.
Rams vs 49ers Over/Under
Rams versus 49ers, on Oct. 2, has an over/under of 43.5, with the over being -118 and the under -104.
Rams vs 49ers Moneyline
Looking at the moneyline for 49ers-Rams, San Francisco is the underdog at +350, and Los Angeles is -450 playing at home.
Rams vs 49ers Betting Trends
- Los Angeles is 3-1-0 against the spread this season.
- Two of the Rams' four games have gone over the point total.
- The 49ers have two wins against the spread this year.
- Two 49ers games (out of four) have hit the over this year.
Check out even more in-depth Rams vs. 49ers analysis on FanDuel Research.
Rams vs 49ers Odds & Spread
- All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: LAR: (-450) | SF: (+350)
- Spread: LAR: -8.5 (-105) | SF: +8.5 (-115)
- Total: 43.5 -- Over: (-118) | Under: (-104)
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