Pirates vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for April 19

Odds updated as of 3:11 p.m.

The Pittsburgh Pirates versus the Cleveland Guardians is on the MLB schedule for Saturday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information regarding this matchup.

Pirates vs Guardians Game Info

• Pittsburgh Pirates (8-13) vs. Cleveland Guardians (10-9)
• Date: Saturday, April 19, 2025
• Time: 4:05 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and CLEG

Pirates vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-172) | CLE: (+144)
• Spread: PIT: -1.5 (+118) | CLE: +1.5 (-142)
• Total: 8 -- Over: (-115) | Under: (-105)

Pirates vs Guardians Probable Starting Pitchers

Probable Pitchers: Paul Skenes (Pirates) - 2-1, 2.96 ERA vs Ben Lively (Guardians) - 0-2, 4.87 ERA

This contest's pitching matchup is set, as the Pirates will send Paul Skenes (2-1) to the mound, while Ben Lively (0-2) will answer the bell for the Guardians. Skenes and his team are 2-2-0 ATS this season when he starts. Skenes' team has a record of 2-2 this season when he starts and they are the favorite on the moneyline. The Guardians have a 1-3-0 record against the spread in Lively's starts. The Guardians have been the moneyline underdog in three of Lively's starts this season, and they went 1-2 in those matchups.

Pirates vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (58.5%)

Pirates vs Guardians Moneyline

• Cleveland is a +144 underdog on the moneyline, while Pittsburgh is a -172 favorite at home.

Pirates vs Guardians Spread

• The Guardians are at +1.5 on the runline against the Pirates. The Guardians are -142 to cover the spread, and the Pirates are +118.

Pirates vs Guardians Over/Under

• Pirates versus Guardians, on April 19, has an over/under of 8, with the over being -115 and the under -105.

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Pirates vs Guardians Betting Trends

• The Pirates have been victorious in five of the nine contests they have been chosen as favorites in this season.
• Pittsburgh has played as a favorite of -172 or more just one time this year and came away with a win in that game.
• Contests with the Pirates have gone over the total set by sportsbooks in nine of 21 chances this season.
• The Pirates have posted a record of 6-15-0 against the spread this season.
• The Guardians have been the underdog on the moneyline 10 total times this season. They've gone 3-7 in those games.
• Cleveland has played as a moneyline underdog of +144 or longer in just two games this season, which it lost both.
• The Guardians have had an over/under set by bookmakers 19 times, and have combined with opponents to go over the total in 10 of those games (10-8-1).
• The Guardians have put together an 8-11-0 record ATS this season (covering 42.1% of the time).

Pirates Player Leaders

• Oneil Cruz has 14 hits and an OBP of .355, both of which are tops among Pittsburgh hitters this season. He has a .230 batting average and a slugging percentage of .508.
• Among qualified hitters in the majors, his batting average ranks 94th, his on-base percentage ranks 51st, and he is 37th in slugging.
• Cruz has hit safely in three games in a row. In his last five games he is hitting .300 with a double, three home runs, two walks and six RBI.
• Isiah Kiner-Falefa has an OPS of .657, fueled by an OBP of .329 and a team-best slugging percentage of .328 this season. He's batting .269.
• Among all qualified, he is 61st in batting average, 77th in on-base percentage and 135th in slugging percentage.
• Kiner-Falefa heads into this game looking to extend his three-game hit streak. During his last five outings he is batting .294 with a double and an RBI.
• Ke'Bryan Hayes has collected 13 base hits, an OBP of .270 and a slugging percentage of .284 this season.
• Enmanuel Valdez has been key for Pittsburgh with 10 hits, an OBP of .327 plus a slugging percentage of .442.
• Valdez has safely hit in three games in a row. In his last five games he is batting .375 with two doubles, a home run, four walks and six RBI.

Guardians Player Leaders

• Steven Kwan has accumulated a .378 on-base percentage and a .467 slugging percentage, both team-best marks for the Guardians. He's batting .320.
• He is 19th in batting average, 32nd in on-base percentage and 52nd in slugging percentage among all qualified hitters in the big leagues.
• Jose Ramirez has racked up 17 hits to pace his team. He has a batting average of .266 while slugging .516 with an on-base percentage of .333.
• He is currently 64th in batting average, 71st in on-base percentage and 33rd in slugging percentage among all qualifying hitters.
• Kyle Manzardo is batting .190 with two doubles, a triple, four home runs and 11 walks.
• Carlos Santana is batting .260 with two doubles, two home runs and eight walks.

Pirates vs Guardians Head to Head

• 4/18/2025: 10-7 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/1/2024: 6-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/31/2024: 3-0 PIT (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 8/30/2024: 10-8 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 7/19/2023: 7-5 PIT (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/18/2023: 10-1 CLE (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

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