Padres vs Rays Prediction, Odds, Moneyline, Spread & Over/Under for April 25

Odds updated as of 9:11 p.m.

On Friday in MLB, the San Diego Padres are playing the Tampa Bay Rays.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Padres vs Rays Game Info

• San Diego Padres (17-8) vs. Tampa Bay Rays (11-14)
• Date: Friday, April 25, 2025
• Time: 9:40 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA and FDSSUN

Padres vs Rays Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-144) | TB: (+122)
• Spread: SD: -1.5 (+155) | TB: +1.5 (-188)
• Total: 7 -- Over: (-108) | Under: (-112)

Padres vs Rays Probable Starting Pitchers

Probable Pitchers: Michael King (Padres) - 3-0, 2.57 ERA vs Shane Austin Baz (Rays) - 2-0, 3.22 ERA

The probable pitchers are Michael King (3-0) for the Padres and Shane Austin Baz (2-0) for the Rays. King and his team are 3-2-0 ATS this season when he starts. King's team has a record of 3-1 this season when he starts and they are the favorite on the moneyline. The Rays have a 3-1-0 record against the spread in Baz's starts. The Rays have always been the moneyline underdog when Baz starts this season.

Padres vs Rays Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (57.6%)

Padres vs Rays Moneyline

• Tampa Bay is the underdog, +122 on the moneyline, while San Diego is a -144 favorite at home.

Padres vs Rays Spread

• The Padres are hosting the Rays and are favored by 1.5 runs (+155 to cover) on the runline. Tampa Bay is -188 to cover.

Padres vs Rays Over/Under

• An over/under of 7 has been set for Padres-Rays on April 25, with the over being -108 and the under -112.

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Padres vs Rays Betting Trends

• The Padres have come away with 10 wins in the 12 contests they have been listed as the favorites in this season.
• San Diego has not lost in seven games when named as a moneyline favorite of -144 or better.
• The Padres and their opponents have gone over in 10 of their 25 games with a total set by sportsbooks this season.
• The Padres are 15-10-0 against the spread in their 25 games that had a posted line this season.
• The Rays have won three of the nine games they were the moneyline underdog this season (33.3%).
• Tampa Bay has gone 2-3 in games it has played as a moneyline underdog with odds of +122 or longer (40%).
• The Rays have played in 25 games with an over/under set, and have combined with opponents to go over the total 11 times (11-12-2).
• The Rays are 10-15-0 ATS this season.

Padres Player Leaders

• Fernando Tatis Jr. has 31 hits and an OBP of .406 to go with a slugging percentage of .624. All three of those stats lead San Diego hitters this season. He has a .333 batting average, as well.
• Among qualifying hitters, he ranks eighth in batting average, his on-base percentage ranks 13th, and he is fifth in slugging.
• Manny Machado is hitting .283 with nine doubles, two home runs and 10 walks, while slugging .446 with an on-base percentage of .353.
• His batting average ranks 44th among qualified players, his on-base percentage 53rd, and his slugging percentage 58th.
• Xander Bogaerts has 22 hits this season and has a slash line of .259/.347/.353.
• Gavin Sheets has three home runs, 12 RBI and a batting average of .309 this season.

Rays Player Leaders

• Jonathan Aranda has an on-base percentage of .417 and has 22 hits, both team-best figures for the Rays. He's batting .314 and slugging .600.
• Including all qualified hitters, he ranks 18th in batting average, while his on-base percentage ranks ninth and he is ninth in slugging.
• Kameron Misner is hitting .349 with seven doubles, a triple, three home runs and five walks. He's slugging .635 with an on-base percentage of .394.
• Yandy (Fernandez) Diaz has a .400 slugging percentage, which paces the Rays.
• Junior Caminero is batting .250 with four doubles, five home runs and six walks.

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