Padres vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for NL Wild Card Game 1 on Sept. 30

Odds updated as of 9:11 p.m.

The MLB slate on Wednesday includes the San Diego Padres facing the Chicago Cubs for Game 2 of the NL Wild Card Series.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Padres vs Cubs Game Info

• San Diego Padres (91-71) vs. Chicago Cubs (89-73)
• Date: Wednesday, September 30, 2026
• Time: 10 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: NBCSN and Peacock

Padres vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-146) | CHC: (+124)
• Spread: SD: -1.5 (+146) | CHC: +1.5 (-178)
• Total: 7.5 -- Over: (+104) | Under: (-128)

Padres vs Cubs Probable Starting Pitchers

Probable Pitchers: Nick Pivetta (Padres) - 3-2, 2.86 ERA vs Kevin Gausman (Cubs) - 9-12, 4.51 ERA

The Padres will look to Nick Pivetta (3-2, 2.86 ERA) against the Cubs and Kevin Gausman (9-12, 4.51 ERA). Pivetta's team is 5-3-0 against the spread this season in his starts. Pivetta's team has won each of the five games he's started as the moneyline favorite. The Cubs have gone 13-19-0 ATS in Gausman's 32 starts with a set spread. The Cubs are 2-8 in Gausman's 10 starts this season that they were the moneyline underdog.

Padres vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (53.3%)

Padres vs Cubs Moneyline

• San Diego is a -146 favorite on the moneyline, while Chicago is a +124 underdog on the road.

Padres vs Cubs Spread

• The Padres are hosting the Cubs and are favored by 1.5 runs on the spread. The Padres are +146 to cover the runline, with the Cubs being -178.

Padres vs Cubs Over/Under

• Padres versus Cubs, on Sept. 30, has an over/under of 7.5, with the over being +104 and the under -128.

Bet on San Diego Padres vs. Chicago Cubs on FanDuel today!

Padres vs Cubs Betting Trends

• The Padres have been favorites in 81 games this season and have come away with the win 50 times (61.7%) in those contests.
• This season San Diego has come away with a win 24 times in 33 chances when named as a favorite of at least -146 on the moneyline.
• The Padres and their opponents have gone over in 78 of their 163 games with a total set by sportsbooks this season.
• The Padres are 95-68-0 against the spread in their 163 games with a line set by sportsbooks this season.
• The Cubs have put together a 23-23 record in games they were the underdog on the moneyline (winning 50% of those games).
• When playing as a moneyline underdog with odds of +124 or longer, Chicago has a 6-4 record (winning 60% of its games).
• The Cubs have combined with opponents to go over the total 90 times this season for a 90-68-0 record against the over/under.
• The Cubs are 74-84-0 against the spread this season.

Padres Player Leaders

• Fernando Tatis Jr. has an OPS of .828, fueled by an OBP of .358 and a team-best slugging percentage of .470 this season. He has a .289 batting average.
• Among all qualified hitters, he ranks 13th in batting average, his on-base percentage ranks 36th, and he is 34th in slugging.
• Jackson Merrill is batting .254 with 26 doubles, five triples, 26 home runs and 41 walks. He's slugging .440 with an on-base percentage of .303.
• He is 74th in batting average, 113th in on-base percentage and 56th in slugging in MLB.
• Merrill brings a four-game streak with at least one hit into this contest. In his last five games he is hitting .333 with a double, a walk and three RBIs.
• Manny Machado has 128 hits this season and has a slash line of .217/.303/.407.
• Machado heads into this game with three games in a row with at least one hit. During his last five outings he is hitting .278 with a double, two home runs, a walk and six RBIs.
• Xander Bogaerts has been key for San Diego with 120 hits, an OBP of .332 plus a slugging percentage of .344.
• Bogaerts has safely hit in three straight games. In his last five games he is batting .357 with two home runs, four walks and two RBIs.

Cubs Player Leaders

• Pete Crow-Armstrong has 175 hits with a .372 on-base percentage and a .570 slugging percentage, all club-highs for the Cubs. He's batting .280.
• Including all the qualifying hitters in the majors, his batting average is 26th, his on-base percentage ranks 14th, and he is second in slugging.
• Alex Bregman is batting .265 with 33 doubles, two triples, 28 home runs and 76 walks. He's slugging .464 with an on-base percentage of .355.
• He is 48th in batting average, 39th in on-base percentage and 39th in slugging percentage in the majors.
• Seiya Suzuki is batting .270 with 31 doubles, a triple, 26 home runs and 81 walks.
• Nico Hoerner is hitting .263 with 29 doubles, a triple, eight home runs and 43 walks.

Padres vs Cubs Head to Head

• 9/29/2026: 8-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 7/1/2026: 23-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 12, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/30/2026: 9-7 CHC (Favorite: Cubs, Spread: -1.5, Total: 11.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 6/29/2026: 3-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 11.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 4/29/2026: 5-4 CHC (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/28/2026: 8-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 4/27/2026: 9-7 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 10/2/2025: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 10/1/2025: 3-0 SD (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/30/2025: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -126, Underdog Moneyline: +108)

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