Padres vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for May 14

Odds updated as of 9:11 a.m.

MLB action on Wednesday includes the San Diego Padres taking on the Los Angeles Angels.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Padres vs Angels Game Info

• San Diego Padres (26-15) vs. Los Angeles Angels (17-24)
• Date: Wednesday, May 14, 2025
• Time: 9:40 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA and FDSW

Padres vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-184) | LAA: (+154)
• Spread: SD: -1.5 (+112) | LAA: +1.5 (-134)
• Total: 8.5 -- Over: (-124) | Under: (+102)

Padres vs Angels Probable Starting Pitchers

Probable Pitchers: Randy Vasquez (Padres) - 2-3, 3.76 ERA vs Kyle Hendricks (Angels) - 1-4, 5.30 ERA

The Padres will call on Randy Vasquez (2-3) versus the Angels and Kyle Hendricks (1-4). Vasquez and his team are 4-3-0 ATS this season when he starts. Vasquez's team won his only start as a favorite this season. The Angels have gone 4-3-0 against the spread when Hendricks starts. The Angels are 3-4 in Hendricks' seven starts this season that they were the moneyline underdog.

Padres vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (66.3%)

Padres vs Angels Moneyline

• The Padres vs Angels moneyline has San Diego as a -184 favorite, while Los Angeles is a +154 underdog on the road.

Padres vs Angels Spread

• The Padres are 1.5-run home favorites on the runline against the Angels. The Padres are +112 to cover, and the Angels are -134.

Padres vs Angels Over/Under

• Padres versus Angels, on May 14, has an over/under of 8.5, with the over being -124 and the under +102.

Bet on San Diego Padres vs. Los Angeles Angels on FanDuel today!

Padres vs Angels Betting Trends

• The Padres have come away with 15 wins in the 21 contests they have been listed as the favorites in this season.
• San Diego has a record of 5-2 when favored by -184 or more this year.
• The Padres and their opponents have hit the over in 19 of their 40 games with a total set by oddsmakers this season.
• In 40 games with a line this season, the Padres have a mark of 24-16-0 against the spread.
• The Angels have been the underdog on the moneyline 33 total times this season. They've finished 13-20 in those games.
• In games it has played as a moneyline underdog with odds of +154 or longer, Los Angeles has gone 2-4 (33.3%).
• The Angels have combined with opponents to hit the over on the total 23 times this season for a 23-17-1 record against the over/under.
• The Angels have a 16-25-0 record ATS this season (covering just 39% of the time).

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego with 49 hits, batting .316 this season with 17 extra-base hits. He has an on-base percentage of .389 and a slugging percentage of .574.
• Among qualified batters in baseball, he ranks ninth in batting average, 16th in on-base percentage, and eighth in slugging.
• Tatis hopes to build on a seven-game hitting streak in this matchup. During his last 10 games he is hitting .238 with two doubles, three home runs, four walks and eight RBIs.
• Manny Machado is slashing .331/.396/.483 this season and leads the Padres with an OPS of .880.
• His batting average is seventh among qualified players, his on-base percentage 11th, and his slugging percentage 35th.
• Machado brings a 13-game streak with at least one hit into this contest. During his last 10 outings he is batting .500 with four doubles, a home run, six walks and seven RBIs.
• Luis Arraez has collected 41 base hits, an OBP of .325 and a slugging percentage of .406 this season.
• Arraez takes a two-game hitting streak into this game. In his last five games he is batting .320 with a triple and three RBIs.
• Xander Bogaerts is batting .243 with a .333 OBP and 17 RBI for San Diego this season.

Angels Player Leaders

• Nolan Schanuel has accumulated a .348 on-base percentage and a .368 slugging percentage, both team-high numbers for the Angels. He's batting .265.
• Including all qualified players, he is 62nd in batting average, while his on-base percentage is 57th and he is 119th in slugging.
• Joseph Ward is batting .185 with six doubles, nine home runs and nine walks. He's slugging .395 with an on-base percentage of .226.
• Including all qualifying players, he ranks 153rd in batting average, 160th in on-base percentage and 97th in slugging percentage.
• Zach Neto is batting .278 with five doubles, six home runs and five walks.
• Jorge Soler is batting .221 with eight doubles, six home runs and 13 walks.

Padres vs Angels Head to Head

• 5/13/2025: 6-4 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 5/12/2025: 9-5 LAA (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 6/5/2024: 3-2 LAA (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/4/2024: 4-2 LAA (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 6/3/2024: 2-1 LAA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 7/5/2023: 5-3 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 7/4/2023: 8-5 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 7/3/2023: 10-3 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -200, Underdog Moneyline: +168)

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