Padres vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for May 12

Odds updated as of 9:12 p.m.

Monday's slate in the MLB includes a matchup between the San Diego Padres and the Los Angeles Angels.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Padres vs Angels Game Info

• San Diego Padres (25-14) vs. Los Angeles Angels (16-23)
• Date: Monday, May 12, 2025
• Time: 9:40 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA and FDSW

Padres vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-215) | LAA: (+180)
• Spread: SD: -1.5 (-102) | LAA: +1.5 (-118)
• Total: 7 -- Over: (-100) | Under: (-122)

Padres vs Angels Probable Starting Pitchers

Probable Pitchers: Michael King (Padres) - 4-1, 2.22 ERA vs Yusei Kikuchi (Angels) - 0-4, 3.83 ERA

This contest's pitching matchup is set, as the Padres will send Michael King (4-1) to the mound, while Yusei Kikuchi (0-4) will take the ball for the Angels. King's team is 4-4-0 against the spread in his starts this season. King's team is 4-2 this season when he starts and they are the moneyline favorite. The Angels have a 3-5-0 record against the spread in Kikuchi's starts. The Angels are 1-5 in Kikuchi's six starts this season that they were the moneyline underdog.

Padres vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (68.5%)

Padres vs Angels Moneyline

• The moneyline numbers for Padres vs. Angels reveal San Diego as the favorite (-215) and Los Angeles as the underdog (+180) on the road.

Padres vs Angels Spread

• The Angels are +1.5 on the run line against the Padres. The Angels are -118 to cover, and the Padres are -102.

Padres vs Angels Over/Under

• The over/under for the Padres versus Angels contest on May 12 has been set at 7, with -100 odds on the over and -122 odds on the under.

Bet on San Diego Padres vs. Los Angeles Angels on FanDuel today!

Padres vs Angels Betting Trends

• The Padres have won in 14, or 73.7%, of the 19 contests they have been named as odds-on favorites in this year.
• This season San Diego has come away with a win two times in three chances when named as a favorite of at least -215 on the moneyline.
• The Padres' games have gone over the total in 17 of their 38 opportunities.
• The Padres are 23-15-0 against the spread in their 38 games with a line set by sportsbooks this season.
• The Angels have a 12-19 record in games they were the underdog on the moneyline (winning 38.7% of those games).
• Los Angeles has not played a game this season with moneyline odds of +180 or longer.
• The Angels have played in 39 games with an over/under set, and have combined with their opponents to go over the total 21 times (21-17-1).
• The Angels have a 15-24-0 record against the spread this season.

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego with 47 hits and an OBP of .388, plus a team-best slugging percentage of .551. He's batting .320.
• Among qualifying hitters in the majors, he ranks eighth in batting average, 15th in on-base percentage, and 10th in slugging.
• Tatis has recorded a base hit in five games in a row. In his last five games he is hitting .333 with a double, a home run, two walks and five RBIs.
• Manny Machado has an OPS of .868, fueled by an OBP of .385 and a team-best slugging percentage of .483 this season. He's batting .324.
• Among qualified hitters, his batting average ranks him seventh, his on-base percentage 17th, and his slugging percentage 33rd.
• Machado takes an 11-game streak with at least one hit into this matchup. In his last 10 games he is batting .447 with four doubles, a home run, five walks and eight RBIs.
• Luis Arraez has collected 39 base hits, an OBP of .329 and a slugging percentage of .415 this season.
• Xander Bogaerts is batting .244 with a .331 OBP and 16 RBI for San Diego this season.

Angels Player Leaders

• Nolan Schanuel has a .342 on-base percentage and a .367 slugging percentage, both team-high numbers for the Angels. He's batting .258.
• Including all the qualifying hitters in the big leagues, he ranks 76th in batting average, 68th in on-base percentage and 125th in slugging percentage.
• Joseph Ward is batting .182 with six doubles, eight home runs and nine walks. He's slugging .385 with an on-base percentage of .226.
• Including all qualified hitters, his batting average places him 156th, his on-base percentage is 163rd, and he is 104th in slugging.
• Jorge Soler has eight doubles, six home runs and 11 walks while hitting .226.
• Logan O'Hoppe has 32 hits to pace his team.

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