New Orleans Saints Vs. Buffalo Bills Odds, Betting Lines, Score & Stats (September 28, 2025)

Bet Success

Type

B. CooksBrandin Cooks

Game

Season

+900

A. KamaraAlvin Kamara

Game

Season

+125

C. SamuelCurtis Samuel

Game

Season

+1200

J. AllenJosh Allen

Game

Season

-160

D. KnoxDawson Knox

Game

Season

+700

T. JohnsonTy Johnson

Game

Season

+490

Game Leaders

Passing Yards
Name	COMP/ATT	PASS YDS	PASS TDS
QB Josh Allen	16/22	209	2
QB Spencer Rattler	18/27	126	1

Rushing Yards
Name	ATT	RUSH YDS	RUSH TDS
RB James Cook	22	117	1
RB Alvin Kamara	15	70	0

Receiving Yards
Name	REC	REC YDS	REC TDS
WR Khalil Shakir	5	69	1
WR Rashid Shaheed	4	47	0

NFL

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• 1d

CJ Stroud is likely to return for a huge Week 13 matchup between the Texans and Colts. Where can we find betting value in that game and elsewhere?

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2 Best NFL Touchdown Prop Bets for Thanksgiving Day

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3 Best NFL Player Prop Bets for Thanksgiving

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3 Best NFL Bets and Player Props for Chiefs at Cowboys on Thanksgiving

2 Best NFL Bets and Player Props for Packers at Lions on Thanksgiving

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• 1d

2 Best NFL Bets and Player Props for Packers at Lions on Thanksgiving

2 Best NFL Bets and Player Props for Bengals at Ravens on Thanksgiving

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• 1d

2 Best NFL Bets and Player Props for Bengals at Ravens on Thanksgiving

2 Best NFL Bets and Predictions for Thanksgiving Day

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• 2d

2 Best NFL Bets and Predictions for Thanksgiving Day

FanDuel NFL DFS Picks: Thanksgiving Main Slate

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• 1d

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10 Best Fantasy Football Waiver Wire Adds Heading Into NFL Week 13

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• 3d

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NFL Week 13 Spread and Total Predictions for Every Game

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• 2d

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Week 13 NFL Odds: Predictions, Spreads, Moneylines, and Totals for Each Game

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• 3d

Week 13 NFL Odds: Predictions, Spreads, Moneylines, and Totals for Each Game

Final

NO

0-0

FINAL

BUF

0-0

FINAL

	Q1	Q2	Q3	Q4
BUF	14	0	7	10
NO	7	3	6	3

New Orleans Saints

2-9 | 4th in NFC South | 15th in NFC

SpreadMoneylineTotal

+14.5

-110

+900

O 48.5

-108

Buffalo Bills

7-4 | 2nd in AFC East | 7th in AFC

SpreadMoneylineTotal

-14.5

-110

-1600

U 48.5

-112

CBS

Highmark Stadium

73ºF | 56% Humidity

7 mph