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Buffalo Bills Vs. Cleveland Browns Odds, Betting Lines, Score & Stats (December 21, 2025) | FanDuel Research

FanDuel Research>
NFL>
Matchups>
Buffalo Bills Vs. Cleveland Browns

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More NFL Games

Game Log

Odds not available yet.

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Type

Passing Yards

Receiving Yards

Rushing Yards

Passing Touchdowns

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

Popular Bets

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4 Leg Parlay

+2000

Player

Any Time Touchdown Scorer

Player 40+ Yards

Player - Alt Rushing Yds

Player 250+ Yards

Player - Alt Passing Yds

Player 5+ Receptions

Player - Alt Receptions

1425 People Placed

4 Leg Parlay

+2000

Player

Any Time Touchdown Scorer

Player 40+ Yards

Player - Alt Rushing Yds

Player 250+ Yards

Player - Alt Passing Yds

Player 5+ Receptions

Player - Alt Receptions

1425 People Placed

Line Movement

These graphs show how the spread, moneyline, and total have shifted at FanDuel Sportsbook over time.

Spread

Bills

Open: -

Browns

Open: -

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Moneyline

Bills

Open: -

Browns

Open: -

Odds not available yet.

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Total

Over

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Under

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Buffalo Bills

20.4 Points

16.0 Points

WRKhalil Shakir

9.9 Points

TEDalton Kincaid

6.8 Points

Cleveland Browns

QBShedeur Sanders

13.7 Points

RBQuinshon Judkins

12.3 Points

TEHarold Fannin Jr.

8.6 Points

7.3 Points

BUF

CLE

-

Offensive EPA

-

-

Passing EPA

-

-

Rushing EPA

-

-

Defensive EPA

-

-

Def Pass EPA

-

-

Def Rush EPA

-

NFL

4 Best NFL Bets and Predictions for Week 13

4 Best NFL Bets and Predictions for Week 13

Jim Sannes

• 1d

CJ Stroud is likely to return for a huge Week 13 matchup between the Texans and Colts. Where can we find betting value in that game and elsewhere?

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• 1d

2 Best NFL Touchdown Prop Bets for Thanksgiving Day

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3 Best NFL Bets and Player Props for Chiefs at Cowboys on Thanksgiving

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3 Best NFL Bets and Player Props for Chiefs at Cowboys on Thanksgiving

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• 1d

2 Best NFL Bets and Player Props for Packers at Lions on Thanksgiving

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• 1d

2 Best NFL Bets and Player Props for Bengals at Ravens on Thanksgiving

2 Best NFL Bets and Predictions for Thanksgiving Day

Jim Sannes

• 2d

2 Best NFL Bets and Predictions for Thanksgiving Day

FanDuel NFL DFS Picks: Thanksgiving Main Slate

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FanDuel NFL DFS Picks: Thanksgiving Main Slate

10 Best Fantasy Football Waiver Wire Adds Heading Into NFL Week 13

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NFL Week 13 Spread and Total Predictions for Every Game

Jim Sannes

• 2d

NFL Week 13 Spread and Total Predictions for Every Game

Week 13 NFL Odds: Predictions, Spreads, Moneylines, and Totals for Each Game

FanDuel Staff

• 3d

Week 13 NFL Odds: Predictions, Spreads, Moneylines, and Totals for Each Game

Buffalo Bills

NameStatus

WRCurtis Samuel

QElbow

KTyler Bass

IRHip

SAFTaylor Rapp

IRKnee

DTEd Oliver

IRBiceps

WRMecole Hardman Jr.

IRCalf

SAFDamar Hamlin

IRPectoral

Cleveland Browns

NameStatus

TEDavid Njoku

QKnee

WRDeAndre Carter

IRKnee

TEBrenden Bates

OAnkle

RBJerome Ford

QHamstring

LBNathaniel Watson

IRBiceps

CBTyson Campbell

QHip

CBS

Buffalo Bills

7-4 | 2nd in AFC East | 7th in AFC

SpreadMoneylineTotal

@

Cleveland Browns

3-8 | 4th in AFC North | 13th in AFC

SpreadMoneylineTotal

CBS

Huntington Bank Field

Buffalo Bills

DateOpponentResultSpread

@

HOUL 19 - 23-4.5

vs

TBW 32 - 44-5.5

@

MIAL 13 - 30-9.5

vs

KCW 21 - 28+2.5

@

CARW 40 - 9-7.5

@

ATLL 14 - 24-3.5

Cleveland Browns

DateOpponentResultSpread

@

LVW 24 - 10+3.5

vs

BALL 23 - 16+8.5

@

NYJL 20 - 27+1.5

@

NEL 13 - 32+7

vs

MIAW 6 - 31-2.5

@

PITL 9 - 23+5.5