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Tennessee Titans Vs. San Francisco 49ers Odds, Betting Lines, Score & Stats (December 14, 2025) | FanDuel Research

FanDuel Research>
NFL>
Matchups>
Tennessee Titans Vs. San Francisco 49ers

Featured Player Props

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Game Log

Popular Bets

Odds not available yet.

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4 Leg Parlay

+2000

Player

Any Time Touchdown Scorer

Player 40+ Yards

Player - Alt Rushing Yds

Player 250+ Yards

Player - Alt Passing Yds

Player 5+ Receptions

Player - Alt Receptions

1425 People Placed

4 Leg Parlay

+2000

Player

Any Time Touchdown Scorer

Player 40+ Yards

Player - Alt Rushing Yds

Player 250+ Yards

Player - Alt Passing Yds

Player 5+ Receptions

Player - Alt Receptions

1425 People Placed

Odds not available yet.

Check back closer to game time!

Type

Passing Yards

Receiving Yards

Rushing Yards

Passing Touchdowns

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

Thanksgiving Pass The Leg NFL Parlay/SGP Profit Boost

NHL Parlay/SGP Profit Boost

NFL Thanksgiving Choose Your Own Reward

NFL $2M Touchdown Jackpot

Tennessee Titans

12.9 Points

9.0 Points

WRElic Ayomanor

7.0 Points

6.9 Points

San Francisco 49ers

RBChristian McCaffrey

21.6 Points

20.5 Points

WRBrandon Aiyuk

10.9 Points

TEGeorge Kittle

9.8 Points

NFL

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TEN

SF

-

Offensive EPA

-

-

Passing EPA

-

-

Rushing EPA

-

-

Defensive EPA

-

-

Def Pass EPA

-

-

Def Rush EPA

-

FOX

Tennessee Titans

1-10 | 4th in AFC South | 16th in AFC

SpreadMoneylineTotal

@

San Francisco 49ers

8-4 | 3rd in NFC West | 7th in NFC

SpreadMoneylineTotal

FOX

Levi's Stadium

Line Movement

These graphs show how the spread, moneyline, and total have shifted at FanDuel Sportsbook over time.

Spread

Titans

Open: -

49ers

Open: -

Odds not available yet.

Check back closer to game time!

Moneyline

Titans

Open: -

49ers

Open: -

Odds not available yet.

Check back closer to game time!

Total

Over

Open: -

Under

Open: -

Odds not available yet.

Check back closer to game time!

Tennessee Titans

NameStatus

SAFXavier Woods

QHamstring

DTShy Tuttle

QHead

WRCalvin Ridley

IRLower Leg

CBL'Jarius Sneed

IRQuadriceps

QBWill Levis

IRShoulder

WRBryce Oliver

IRKnee

San Francisco 49ers

NameStatus

WRTrent Taylor

IRUndisclosed

LBFred Warner

IRAnkle

KEddy Pineiro

QHamstring

RBPatrick Taylor Jr.

IRShoulder

DLNick Bosa

IRKnee - ACL

DLYetur Gross-Matos

IRKnee

Tennessee Titans

DateOpponentResultSpread

vs

SEAL 30 - 24+12.5

vs

HOUL 16 - 13+7.5

vs

LACL 27 - 20+10.5

@

INDL 14 - 38+14.5

vs

NEL 31 - 13+7

@

LVL 10 - 20+5.5

San Francisco 49ers

DateOpponentResultSpread

vs

CARW 9 - 20-7.5

@

ARIW 41 - 22-3

vs

LARL 42 - 26+3.5

@

NYGW 34 - 24-2.5

@

HOUL 15 - 26-1.5

vs

ATLW 10 - 20-3