NFL Games This Week: Predictions, Odds, Picks, Best Bets for Divisional Round

The NFL Playoffs Divisional slate has plenty of exciting matchups in store. Among those contests is the San Francisco 49ers taking on the Seattle Seahawks.

Trying to find an edge in the NFL? We break down the betting odds for each of the important matchups below.

Broncos vs. Bills

The Buffalo Bills (12-5) will look to go on the road and win in the playoffs against the Denver Broncos (14-3) in the AFC Divisional round on Jan. 17 at 4:30 p.m. ET at Empower Field at Mile High.

• Game Preview: Buffalo Bills at Denver Broncos
• Projected Favorite: Broncos (64.04% win probability)
• Spread: Denver (-1.5)
• Total: 45.5 -- Over: (-115) | Under: (-105)
• Time: 4:30 p.m. ET
• Channel: CBS

Bet on Denver vs. Buffalo with FanDuel Sportsbook.

Seahawks vs. 49ers

The San Francisco 49ers (12-5) will look to go on the road and win in the playoffs against the Seattle Seahawks (14-3) in the NFC Divisional round on Jan. 17 at 8 p.m. ET at Lumen Field.

• Game Preview: San Francisco 49ers at Seattle Seahawks
• Spread: Seattle (-6.5)
• Total: 44.5 -- Over: (-105) | Under: (-115)
• Time: 8 p.m. ET
• Channel: FOX

Bet on Seattle vs. San Francisco with FanDuel Sportsbook.

Patriots vs. Texans

The AFC Divisional round of the NFL Playoffs will see the Houston Texans (12-5) and New England Patriots (14-3) take the field at Gillette Stadium on Jan. 18 at 3 p.m. ET.

• Game Preview: Houston Texans at New England Patriots
• Projected Favorite: Patriots (68.02% win probability)
• Spread: New England (-3.5)
• Total: 40.5 -- Over: (-114) | Under: (-106)
• Time: 3 p.m. ET
• Channel: ABC/ESPN

Bet on New England vs. Houston with FanDuel Sportsbook.

Bears vs. Rams

The NFC Divisional round of the NFL Playoffs will see the Chicago Bears (11-6) and Los Angeles Rams (12-5) meet at Soldier Field on Jan. 18 at 6:30 p.m. ET.

• Game Preview: Los Angeles Rams at Chicago Bears
• Projected Favorite: Rams (63.73% win probability)
• Spread: Los Angeles (-3.5)
• Total: 48.5 -- Over: (-110) | Under: (-110)
• Time: 6:30 p.m. ET
• Channel: NBC/Peacock

Bet on Chicago vs. Los Angeles with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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