Giants vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for May 10

Odds updated as of 6:11 a.m.

On Saturday in MLB, the San Francisco Giants are playing the Minnesota Twins.

We've got you covered, in terms of the vital information regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Giants vs Twins Game Info

• San Francisco Giants (24-15) vs. Minnesota Twins (19-20)
• Date: Saturday, May 10, 2025
• Time: 7:15 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: FOX

Giants vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-116) | MIN: (-102)
• Spread: SF: -1.5 (+138) | MIN: +1.5 (-166)
• Total: 8.5 -- Over: (-124) | Under: (+102)

Giants vs Twins Probable Starting Pitchers

Probable Pitchers: Logan Webb (Giants) - 4-2, 2.61 ERA vs Joe Ryan (Twins) - 2-2, 2.93 ERA

The probable pitchers are Logan Webb (4-2) for the Giants and Joe Ryan (2-2) for the Twins. Webb and his team are 5-3-0 ATS this season when he starts. When Webb starts a game and his team is the favorite on the moneyline, they have a record of 4-3. The Twins have gone 2-5-0 against the spread when Ryan starts. The Twins were named the moneyline underdog for two Ryan starts this season -- they lost both.

Giants vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (53.1%)

Giants vs Twins Moneyline

• San Francisco is the favorite, -116 on the moneyline, while Minnesota is a -102 underdog despite being at home.

Giants vs Twins Spread

• The Twins are +1.5 on the spread (-166 to cover), and San Francisco is +138 to cover the runline.

Giants vs Twins Over/Under

• A total of 8.5 runs has been set for the Giants-Twins game on May 10, with the over available at -124 and the under at +102.

Bet on San Francisco Giants vs. Minnesota Twins on FanDuel today!

Giants vs Twins Betting Trends

• The Giants have won in 16, or 66.7%, of the 24 contests they have been named as odds-on favorites in this year.
• San Francisco has a record of 15-8 when favored by -116 or more this year.
• The Giants and their opponents have hit the over in 22 of their 39 games with a total set by oddsmakers this season.
• The Giants have an against the spread record of 19-20-0 in 39 games with a line this season.
• The Twins have been the moneyline underdog 11 total times this season. They've finished 4-7 in those games.
• When playing as a moneyline underdog with odds of -102 or longer, Minnesota has gone 3-5 (37.5%).
• In the 38 games bookmakers have set an over/under for the Twins, they have combined with opponents to go over the total 13 times (13-22-3).
• The Twins have put together a 20-18-0 record ATS this season (covering 52.6% of the time).

Giants Player Leaders

• Jung Hoo Lee leads San Francisco with 43 hits and a team-best slugging percentage of .476. He's batting .293 with an on-base percentage of .344.
• Among qualifying batters in the majors, his batting average ranks 26th, his on-base percentage ranks 59th, and he is 38th in slugging.
• Matt Chapman has five doubles, eight home runs and 29 walks. He's batting .222 and slugging .437 with an on-base percentage of .360.
• Among all qualifying hitters, he ranks 125th in batting average, 45th in on-base percentage and 60th in slugging percentage.
• Wilmer Flores is batting .250 with a .419 slugging percentage and 33 RBI this year.
• Michael Yastrzemski has 32 hits this season and a team-best OBP of .377.

Twins Player Leaders

• Byron Buxton has totaled 39 hits with a .550 slugging percentage, both team-best marks for the Twins. He's batting .279 and with an on-base percentage of .322.
• Including all qualified players in the big leagues, he is 43rd in batting average, 86th in on-base percentage and 12th in slugging percentage.
• Ty France paces his team with a .344 on-base percentage, and has a club-best .397 slugging percentage. He has a batting average of .277.
• He is currently 46th in batting average, 59th in on-base percentage and 94th in slugging percentage among all qualified hitters.
• Trevor Larnach is batting .225 with two doubles, five home runs and 16 walks.
• Harrison Bader has four doubles, four home runs and 12 walks while hitting .289.

Giants vs Twins Head to Head

• 5/9/2025: 3-1 MIN (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/14/2024: 3-2 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/13/2024: 4-2 MIN (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/12/2024: 7-1 SF (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/24/2023: 7-1 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 5/23/2023: 4-3 SF (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 5/22/2023: 4-1 SF (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 8/28/2022: 8-3 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/27/2022: 3-2 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/26/2022: 9-0 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +116)

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