Giants vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for May 24

Odds updated as of 3:13 p.m.

MLB action on Saturday includes the San Francisco Giants playing the Washington Nationals.

We've got you covered, in terms of the most important info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Giants vs Nationals Game Info

• San Francisco Giants (30-21) vs. Washington Nationals (23-28)
• Date: Saturday, May 24, 2025
• Time: 4:05 p.m. ET
• Venue: Nationals Park -- Washington, District of Columbia
• Coverage: MASN2 and NBCS-BA

Giants vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-158) | WSH: (+134)
• Spread: SF: -1.5 (+108) | WSH: +1.5 (-130)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Giants vs Nationals Probable Starting Pitchers

Probable Pitchers: Kyle Harrison (Giants) - 0-0, 3.38 ERA vs Jake Irvin (Nationals) - 3-1, 3.88 ERA

This contest's pitching matchup is set, as the Giants will send Kyle Harrison to the mound, while Jake Irvin (3-1) will get the nod for the Nationals. In games Harrison pitched with a spread last season, his team was 16-8-0 ATS. Harrison and his team won 72.7% of the games he started as the moneyline favorite last season, with a record of 8-3. The Nationals have gone 6-4-0 against the spread when Irvin starts. The Nationals are 5-5 in Irvin's 10 starts this season that they were the moneyline underdog.

Giants vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (52.8%)

Giants vs Nationals Moneyline

• Washington is the underdog, +134 on the moneyline, while San Francisco is a -158 favorite despite being on the road.

Giants vs Nationals Spread

• The Nationals are at +1.5 on the runline against the Giants. The Nationals are -130 to cover the spread, and the Giants are +108.

Giants vs Nationals Over/Under

• Giants versus Nationals, on May 24, has an over/under of 8.5, with the over being -110 and the under -110.

Bet on San Francisco Giants vs. Washington Nationals on FanDuel today!

Giants vs Nationals Betting Trends

• The Giants have been victorious in 20, or 62.5%, of the 32 contests they have been chosen as favorites in this season.
• This year San Francisco has won five of eight games when listed as at least -158 on the moneyline.
• The Giants' games have gone over the total in 27 of their 51 opportunities.
• The Giants have an against the spread mark of 25-26-0 in 51 games with a line this season.
• The Nationals have won 52.6% of the games this season they were the moneyline underdog (20-18).
• Washington is 9-9 (winning 50% of its games) when it has played as a moneyline underdog of +134 or longer.
• The Nationals have had an over/under set by bookmakers 49 times, and have combined with opponents to go over the total in 24 of those games (24-24-1).
• The Nationals are 26-23-0 ATS this season.

Giants Player Leaders

• Jung Hoo Lee is hitting .282 with 14 doubles, two triples, six home runs and 14 walks. He has an on-base percentage of .330 while slugging .467.
• Among qualified hitters in MLB, his batting average ranks 38th, his on-base percentage ranks 79th, and he is 48th in slugging.
• Lee has recorded at least one hit in four games in a row. During his last five outings he is batting .278 with two doubles, three walks and two RBIs.
• Wilmer Flores is hitting .257 with two doubles, 10 home runs and 16 walks, while slugging .436 with an on-base percentage of .321.
• Among qualifying hitters, his batting average ranks him 82nd, his on-base percentage 92nd, and his slugging percentage 67th.
• Flores has picked up a hit in four games in a row. During his last five outings he is batting .211 with two walks and an RBI.
• Heliot Ramos leads San Francisco with 56 hits and a team-best slugging percentage of .492.
• Ramos takes an eight-game hitting streak into this game. During his last 10 outings he is batting .350 with a double, two home runs, three walks and seven RBIs.
• Matt Chapman has nine home runs, 25 RBI and a batting average of .219 this season.
• Chapman has safely hit in two straight games. In his last five games he is batting .167 with a home run, two walks and an RBI.

Nationals Player Leaders

• James Wood has racked up a team-high OBP (.382) and slugging percentage (.534). He's batting .285.
• Including all qualifying players in the big leagues, he is 33rd in batting average, 19th in on-base percentage and 17th in slugging percentage.
• C.J. Abrams' 46 hits pace his team. He has a batting average of .303 while slugging .546 with an on-base percentage of .363.
• Including all qualified hitters, his batting average places him 16th, his on-base percentage is 40th, and he is 14th in slugging.
• Nathaniel Lowe is hitting .223 with eight doubles, eight home runs and 19 walks.
• Luis Garcia has nine doubles, four home runs and 11 walks while batting .231.

Giants vs Nationals Head to Head

• 5/23/2025: 4-0 SF (Favorite: Nationals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/8/2024: 9-5 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/7/2024: 7-4 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/6/2024: 11-5 WSH (Favorite: Giants, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/5/2024: 4-1 SF (Favorite: Giants, Spread: -1.5, Total: 9, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/10/2024: 7-1 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 4/9/2024: 5-3 WSH (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/8/2024: 8-1 WSH (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 7/23/2023: 6-1 WSH (Favorite: Giants, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/22/2023: 10-1 WSH (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -196, Underdog Moneyline: +164)

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