Giants vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for May 24

Odds updated as of 2:12 a.m.

The MLB's Saturday schedule includes the San Francisco Giants facing the Washington Nationals.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Giants vs Nationals Game Info

• San Francisco Giants (30-21) vs. Washington Nationals (23-28)
• Date: Saturday, May 24, 2025
• Time: 4:05 p.m. ET
• Venue: Nationals Park -- Washington, District of Columbia
• Coverage: MASN2 and NBCS-BA

Giants vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-136) | WSH: (+116)
• Spread: SF: -1.5 (+126) | WSH: +1.5 (-152)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Giants vs Nationals Probable Starting Pitchers

Probable Pitchers: Kyle Harrison (Giants) - 0-0, 3.38 ERA vs Jake Irvin (Nationals) - 3-1, 3.88 ERA

This contest's pitching matchup is set, as the Giants will send Kyle Harrison to the mound, while Jake Irvin (3-1) will get the nod for the Nationals. Harrison and his team were 16-8-0 ATS in games he pitched last year. Harrison and his team won 72.7% of the games he started as the moneyline favorite last season, with a record of 8-3. The Nationals have gone 6-4-0 ATS in Irvin's 10 starts that had a set spread. The Nationals have a 5-5 record in Irvin's 10 starts this season when they were the underdog on the moneyline.

Giants vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Nationals win (50.8%)

Giants vs Nationals Moneyline

• Washington is a +116 underdog on the moneyline, while San Francisco is a -136 favorite on the road.

Giants vs Nationals Spread

• The Nationals are at +1.5 on the runline against the Giants. The Nationals are -152 to cover the spread, and the Giants are +126.

Giants vs Nationals Over/Under

• An over/under of 8.5 has been set for Giants-Nationals on May 24, with the over being -110 and the under -110.

Bet on San Francisco Giants vs. Washington Nationals on FanDuel today!

Giants vs Nationals Betting Trends

• The Giants have come away with 20 wins in the 32 contests they have been listed as the favorites in this season.
• This season San Francisco has been victorious 14 times in 19 chances when named as a favorite of at least -136 on the moneyline.
• The Giants and their opponents have gone over in 27 of their 51 games with a total set by sportsbooks this season.
• The Giants have an against the spread record of 25-26-0 in 51 games with a line this season.
• The Nationals have been the moneyline underdog 38 total times this season. They've gone 20-18 in those games.
• In games it has played as a moneyline underdog with odds of +116 or longer, Washington has a 14-15 record (winning 48.3% of its games).
• In the 49 games bookmakers have set an over/under for the Nationals, they have combined with opponents to go over the total 24 times (24-24-1).
• The Nationals have covered 53.1% of their games this season, going 26-23-0 ATS.

Giants Player Leaders

• Jung Hoo Lee is batting .282 with 14 doubles, two triples, six home runs and 14 walks. He has an on-base percentage of .330 and a slugging percentage of .467.
• Among qualifying hitters, he is 38th in batting average, his on-base percentage ranks 78th, and he is 48th in slugging.
• Lee hopes to build on a four-game hitting streak in this matchup. In his last five games he is batting .278 with two doubles, three walks and two RBIs.
• Wilmer Flores is hitting .257 with two doubles, 10 home runs and 16 walks, while slugging .436 with an on-base percentage of .321.
• Among qualified hitters, his batting average ranks him 81st, his on-base percentage 91st, and his slugging percentage 67th.
• Flores enters this game looking to extend his four-game hit streak. During his last five outings he is batting .211 with two walks and an RBI.
• Heliot Ramos leads San Francisco with 56 hits and a team-best slugging percentage of .492.
• Ramos has recorded at least one base hit in eight straight games. During his last 10 games he is hitting .350 with a double, two home runs, three walks and seven RBIs.
• Matt Chapman is batting .219 with a .341 OBP and 25 RBI for San Francisco this season.
• Chapman has safely hit in two games in a row. In his last five games he is hitting .167 with a home run, two walks and an RBI.

Nationals Player Leaders

• James Wood has a .382 on-base percentage and a .534 slugging percentage, both team-high numbers for the Nationals. He's batting .285.
• Including all the qualifying hitters in MLB, his batting average places him 32nd, his on-base percentage ranks 18th, and he is 18th in slugging.
• C.J. Abrams has 46 hits to pace his team. He has a batting average of .303 while slugging .546 with an on-base percentage of .363.
• His batting average ranks 16th among all qualified players, his on-base percentage is 39th, and he is 14th in slugging.
• Nathaniel Lowe is batting .223 with eight doubles, eight home runs and 19 walks.
• Luis Garcia has nine doubles, four home runs and 11 walks while hitting .231.

Giants vs Nationals Head to Head

• 5/23/2025: 4-0 SF (Favorite: Nationals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/8/2024: 9-5 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/7/2024: 7-4 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/6/2024: 11-5 WSH (Favorite: Giants, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/5/2024: 4-1 SF (Favorite: Giants, Spread: -1.5, Total: 9, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/10/2024: 7-1 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 4/9/2024: 5-3 WSH (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/8/2024: 8-1 WSH (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 7/23/2023: 6-1 WSH (Favorite: Giants, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/22/2023: 10-1 WSH (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -196, Underdog Moneyline: +164)

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