Giants vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for May 24

Odds updated as of 3:13 p.m.
MLB action on Saturday includes the San Francisco Giants playing the Washington Nationals.
We've got you covered, in terms of the most important info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.
Giants vs Nationals Game Info
- San Francisco Giants (30-21) vs. Washington Nationals (23-28)
- Date: Saturday, May 24, 2025
- Time: 4:05 p.m. ET
- Venue: Nationals Park -- Washington, District of Columbia
- Coverage: MASN2 and NBCS-BA
Giants vs Nationals Odds & Moneyline
- All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: SF: (-158) | WSH: (+134)
- Spread: SF: -1.5 (+108) | WSH: +1.5 (-130)
- Total: 8.5 -- Over: (-110) | Under: (-110)
Giants vs Nationals Probable Starting Pitchers
Probable Pitchers: Kyle Harrison (Giants) - 0-0, 3.38 ERA vs Jake Irvin (Nationals) - 3-1, 3.88 ERA
This contest's pitching matchup is set, as the Giants will send Kyle Harrison to the mound, while Jake Irvin (3-1) will get the nod for the Nationals. In games Harrison pitched with a spread last season, his team was 16-8-0 ATS. Harrison and his team won 72.7% of the games he started as the moneyline favorite last season, with a record of 8-3. The Nationals have gone 6-4-0 against the spread when Irvin starts. The Nationals are 5-5 in Irvin's 10 starts this season that they were the moneyline underdog.
Giants vs Nationals Prediction & Pick
All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (52.8%)
Giants vs Nationals Moneyline
- Washington is the underdog, +134 on the moneyline, while San Francisco is a -158 favorite despite being on the road.
Giants vs Nationals Spread
- The Nationals are at +1.5 on the runline against the Giants. The Nationals are -130 to cover the spread, and the Giants are +108.
Giants vs Nationals Over/Under
- Giants versus Nationals, on May 24, has an over/under of 8.5, with the over being -110 and the under -110.
Bet on San Francisco Giants vs. Washington Nationals on FanDuel today!
Giants vs Nationals Betting Trends
- The Giants have been victorious in 20, or 62.5%, of the 32 contests they have been chosen as favorites in this season.
- This year San Francisco has won five of eight games when listed as at least -158 on the moneyline.
- The Giants' games have gone over the total in 27 of their 51 opportunities.
- The Giants have an against the spread mark of 25-26-0 in 51 games with a line this season.
- The Nationals have won 52.6% of the games this season they were the moneyline underdog (20-18).
- Washington is 9-9 (winning 50% of its games) when it has played as a moneyline underdog of +134 or longer.
- The Nationals have had an over/under set by bookmakers 49 times, and have combined with opponents to go over the total in 24 of those games (24-24-1).
- The Nationals are 26-23-0 ATS this season.
Giants Player Leaders
- Jung Hoo Lee is hitting .282 with 14 doubles, two triples, six home runs and 14 walks. He has an on-base percentage of .330 while slugging .467.
- Among qualified hitters in MLB, his batting average ranks 38th, his on-base percentage ranks 79th, and he is 48th in slugging.
- Lee has recorded at least one hit in four games in a row. During his last five outings he is batting .278 with two doubles, three walks and two RBIs.
- Wilmer Flores is hitting .257 with two doubles, 10 home runs and 16 walks, while slugging .436 with an on-base percentage of .321.
- Among qualifying hitters, his batting average ranks him 82nd, his on-base percentage 92nd, and his slugging percentage 67th.
- Flores has picked up a hit in four games in a row. During his last five outings he is batting .211 with two walks and an RBI.
- Heliot Ramos leads San Francisco with 56 hits and a team-best slugging percentage of .492.
- Ramos takes an eight-game hitting streak into this game. During his last 10 outings he is batting .350 with a double, two home runs, three walks and seven RBIs.
- Matt Chapman has nine home runs, 25 RBI and a batting average of .219 this season.
- Chapman has safely hit in two straight games. In his last five games he is batting .167 with a home run, two walks and an RBI.
Nationals Player Leaders
- James Wood has racked up a team-high OBP (.382) and slugging percentage (.534). He's batting .285.
- Including all qualifying players in the big leagues, he is 33rd in batting average, 19th in on-base percentage and 17th in slugging percentage.
- C.J. Abrams' 46 hits pace his team. He has a batting average of .303 while slugging .546 with an on-base percentage of .363.
- Including all qualified hitters, his batting average places him 16th, his on-base percentage is 40th, and he is 14th in slugging.
- Nathaniel Lowe is hitting .223 with eight doubles, eight home runs and 19 walks.
- Luis Garcia has nine doubles, four home runs and 11 walks while batting .231.
Giants vs Nationals Head to Head
- 5/23/2025: 4-0 SF (Favorite: Nationals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
- 8/8/2024: 9-5 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
- 8/7/2024: 7-4 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
- 8/6/2024: 11-5 WSH (Favorite: Giants, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
- 8/5/2024: 4-1 SF (Favorite: Giants, Spread: -1.5, Total: 9, Favorite Moneyline: -168, Underdog Moneyline: +142)
- 4/10/2024: 7-1 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
- 4/9/2024: 5-3 WSH (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
- 4/8/2024: 8-1 WSH (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
- 7/23/2023: 6-1 WSH (Favorite: Giants, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
- 7/22/2023: 10-1 WSH (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!