Diamondbacks vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 23

Odds updated as of 8:11 p.m.

Wednesday's slate in the MLB includes a matchup between the Arizona Diamondbacks and the Colorado Rockies.

We've got you covered, in terms of the vital info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Diamondbacks vs Rockies Game Info

• Arizona Diamondbacks (83-74) vs. Colorado Rockies (57-100)
• Date: Wednesday, September 23, 2026
• Time: 8:40 p.m. ET
• Venue: Coors Field -- Denver, Colorado
• Coverage: Rockies.TV and Dbacks.TV

Diamondbacks vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-158) | COL: (+134)
• Spread: ARI: -1.5 (-102) | COL: +1.5 (-115)
• Total: 11.5 -- Over: (+110) | Under: (-134)

Diamondbacks vs Rockies Probable Starting Pitchers

Probable Pitchers: Merrill Kelly (Diamondbacks) - 9-14, 5.00 ERA vs Mason Adams (Rockies) - 0-1, 5.09 ERA

This contest's pitching matchup is set, as the Diamondbacks will send Merrill Kelly (9-14) to the mound, while Mason Adams (0-1) will take the ball for the Rockies. Kelly's team is 14-14-0 against the spread in his starts this season. Kelly's team has been victorious in 45.5% of the games he's started as the moneyline favorite with a record of 5-6. The Rockies have a 3-2-0 ATS record in Adams' five starts that had a set spread. The Rockies have a 2-3 record in Adams' five starts this season when they were the moneyline underdog.

Diamondbacks vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (56.9%)

Diamondbacks vs Rockies Moneyline

• Colorado is a +134 underdog on the moneyline, while Arizona is a -158 favorite on the road.

Diamondbacks vs Rockies Spread

• The Diamondbacks are at the Rockies and are favored by 1.5 runs on the spread. The Diamondbacks are -102 to cover the runline, with the Rockies being -115.

Diamondbacks vs Rockies Over/Under

• A combined run total of 11.5 has been set for Diamondbacks-Rockies on Sept. 23, with the over at +110 and the under at -134.

Bet on Arizona Diamondbacks vs. Colorado Rockies on FanDuel today!

Diamondbacks vs Rockies Betting Trends

• The Diamondbacks have been chosen as favorites in 67 games this year and have walked away with the win 38 times (56.7%) in those games.
• This season Arizona has been victorious seven times in 11 chances when named as a favorite of at least -158 on the moneyline.
• The Diamondbacks and their opponents have hit the over in 67 of their 155 games with a total set by oddsmakers this season.
• The Diamondbacks are 81-74-0 against the spread in their 155 games with a line set by sportsbooks this season.
• The Rockies have compiled a 54-96 record in games they were the underdog on the moneyline (winning 36% of those games).
• Colorado has a 26-71 record (winning just 26.8% of its games) when playing as a moneyline underdog of +134 or longer.
• The Rockies have combined with opponents to go over the total 75 times this season for a 75-76-3 record against the over/under.
• The Rockies have an 81-73-0 record ATS this season (covering 52.6% of the time).

Diamondbacks Player Leaders

• Corbin Carroll is batting .240 with 32 doubles, 16 triples, 22 home runs and 72 walks. He has an on-base percentage of .331 while slugging .471.
• Among qualified hitters in the majors, he is 97th in batting average, 68th in on-base percentage, and 29th in slugging.
• Carroll has hit safely in two straight games. In his last five games he is hitting .235 with two doubles, a home run, two walks and six RBIs.
• Gabriel Moreno leads Arizona with 140 hits and an OBP of .384 this season. He's batting .306 and slugging .481.
• Among qualified batters, his batting average ranks him fourth, his on-base percentage sixth, and his slugging percentage 24th.
• Moreno brings a three-game streak with at least one hit into this contest. In his last five games he is batting .389 with two doubles, a home run, two walks and three RBIs.
• Geraldo Perdomo has hit nine homers with a team-high .369 SLG this season.
• Perdomo has recorded a hit in six straight games. During his last 10 games he is batting .378 with a triple, six walks and three RBIs.
• Ketel Marte is batting .249 with a .314 OBP and 74 RBI for Arizona this season.
• Marte heads into this matchup on a two-game hitting streak. During his last five outings he is batting .200 with a walk.

Rockies Player Leaders

• Jake McCarthy is batting .295 with 30 doubles, 13 triples, 15 home runs and 29 walks. He's slugging .486 with an on-base percentage of .338.
• Including all the qualifying hitters in MLB, his batting average ranks eighth, his on-base percentage ranks 57th, and he is 22nd in slugging.
• TJ Rumfield has a .389 OBP while slugging .448. Both are team-highs. He has a batting average of .298.
• Including all qualified hitters, his batting average puts him seventh, his on-base percentage is third, and he is 48th in slugging.
• Hunter Goodman is leading the Rockies with 121 hits.
• Kyle Karros is batting .255 with 21 doubles, three triples, 12 home runs and 52 walks.

Diamondbacks vs Rockies Head to Head

• 9/22/2026: 7-2 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 10.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 8/12/2026: 6-4 COL (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -172, Underdog Moneyline: +158)
• 8/11/2026: 3-2 COL (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -160, Underdog Moneyline: +148)
• 8/10/2026: 9-0 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -205, Underdog Moneyline: +186)
• 5/24/2026: 9-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 5/23/2026: 5-4 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 5/22/2026: 3-2 COL (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 5/21/2026: 2-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 5/16/2026: 4-2 COL (Favorite: Diamondbacks, Spread: -1.5, Total: 11.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/15/2026: 9-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 11.5, Favorite Moneyline: -122, Underdog Moneyline: +104)

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