Cubs vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for May 7

Odds updated as of 11:11 a.m.

In MLB action on Wednesday, the Chicago Cubs take on the San Francisco Giants.

We've got you covered, in terms of the most important info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Giants Game Info

• Chicago Cubs (22-15) vs. San Francisco Giants (23-14)
• Date: Wednesday, May 7, 2025
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and NBCS-BA

Cubs vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-152) | SF: (+128)
• Spread: CHC: -1.5 (+146) | SF: +1.5 (-176)
• Total: 7 -- Over: (-112) | Under: (-108)

Cubs vs Giants Probable Starting Pitchers

Probable Pitchers: Ben Brown (Cubs) - 3-2, 4.88 ERA vs Robbie Ray (Giants) - 4-0, 3.05 ERA

The Cubs will give the nod to Ben Brown (3-2) versus the Giants and Robbie Ray (4-0). Brown's team is 4-2-0 against the spread this season in his starts. Brown's team has been victorious in 75% of the games he's started as the moneyline favorite with a record of 3-1. The Giants have a 6-1-0 ATS record in Ray's seven starts with a set spread. The Giants were the underdog on the moneyline for two Ray starts this season -- they won both.

Cubs vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (59.2%)

Cubs vs Giants Moneyline

• Chicago is a -152 favorite on the moneyline, while San Francisco is a +128 underdog on the road.

Cubs vs Giants Spread

• The Cubs are hosting the Giants and are favored by 1.5 runs on the spread. The Cubs are +146 to cover the runline, with the Giants being -176.

Cubs vs Giants Over/Under

• The over/under for Cubs-Giants on May 7 is 7. The over is -112, and the under is -108.

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Cubs vs Giants Betting Trends

• The Cubs have been chosen as favorites in 18 games this year and have walked away with the win 13 times (72.2%) in those games.
• This season Chicago has come away with a win four times in six chances when named as a favorite of at least -152 on the moneyline.
• The Cubs' games have gone over the total in 23 of their 35 opportunities.
• The Cubs have posted a record of 19-16-0 against the spread this season.
• The Giants have a 7-7 record in games they were listed as the moneyline underdog (winning 50% of those games).
• In games it has played as a moneyline underdog with odds of +128 or longer, San Francisco has a record of 1-3 (25%).
• The Giants have had an over/under set by bookmakers 37 times, and have combined with opponents to go over the total in 22 of those games (22-14-1).
• The Giants have an 18-19-0 record ATS this season.

Cubs Player Leaders

• Kyle Tucker leads Chicago with 42 hits and an OBP of .399 this season. He has a .290 batting average and a slugging percentage of .559.
• Among qualified batters, he is 30th in batting average, his on-base percentage ranks ninth, and he is 11th in slugging.
• Pete Crow-Armstrong is hitting .264 with 10 doubles, a triple, nine home runs and seven walks, while slugging .535 with an on-base percentage of .303.
• Among qualifiers, he ranks 56th in batting average, 108th in on-base percentage and 18th in slugging percentage.
• Carson Kelly has 22 hits this season and has a slash line of .355/.500/.806.
• Ian Happ leads Chicago in slugging percentage (.396) thanks to 12 extra-base hits.

Giants Player Leaders

• Jung Hoo Lee has racked up a slugging percentage of .507 and has 43 hits, both team-best marks for the Giants. He's batting .312 and with an on-base percentage of .364.
• Including all the qualifying hitters in MLB, his batting average is 14th, his on-base percentage is 41st, and he is 25th in slugging.
• Matt Chapman has five doubles, seven home runs and 28 walks while batting .225. He's slugging .426 with an on-base percentage of .363.
• Including all qualifying players, his batting average puts him 115th, his on-base percentage is 43rd, and he is 67th in slugging.
• Michael Yastrzemski a has .385 on-base percentage to lead the Giants.
• Wilmer Flores has two doubles, seven home runs and nine walks while hitting .240.

Cubs vs Giants Head to Head

• 5/6/2025: 14-5 SF (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 5/5/2025: 9-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/27/2024: 5-3 CHC (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/26/2024: 4-3 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/25/2024: 5-1 SF (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 6/24/2024: 5-4 SF (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 6/19/2024: 6-5 CHC (Favorite: Cubs, Spread: -1.5, Total: 11, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 6/18/2024: 5-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/17/2024: 7-6 SF (Favorite: Cubs, Spread: -1.5, Total: 10.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/6/2023: 8-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 11, Favorite Moneyline: -152, Underdog Moneyline: +128)

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