Cubs vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for May 7

Odds updated as of 2:11 p.m.

The MLB slate on Wednesday includes the Chicago Cubs facing the San Francisco Giants.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Giants Game Info

• Chicago Cubs (22-15) vs. San Francisco Giants (23-14)
• Date: Wednesday, May 7, 2025
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and NBCS-BA

Cubs vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-166) | SF: (+140)
• Spread: CHC: -1.5 (+134) | SF: +1.5 (-162)
• Total: 7.5 -- Over: (-106) | Under: (-114)

Cubs vs Giants Probable Starting Pitchers

Probable Pitchers: Ben Brown (Cubs) - 3-2, 4.88 ERA vs Robbie Ray (Giants) - 4-0, 3.05 ERA

The probable pitchers are Ben Brown (3-2) for the Cubs and Robbie Ray (4-0) for the Giants. Brown and his team have a record of 4-2-0 against the spread when he starts. Brown's team has a record of 3-1 this season when he starts and they are the favorite on the moneyline. The Giants have a 6-1-0 record against the spread in Ray's starts. The Giants were the moneyline underdog for two Ray starts this season -- they won both.

Cubs vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (59.2%)

Cubs vs Giants Moneyline

• Chicago is the favorite, -166 on the moneyline, while San Francisco is a +140 underdog on the road.

Cubs vs Giants Spread

• The Cubs are hosting the Giants and are favored by 1.5 runs on the spread. The Cubs are +134 to cover the runline, with the Giants being -162.

Cubs vs Giants Over/Under

• An over/under of 7.5 has been set for Cubs-Giants on May 7, with the over being -106 and the under -114.

Bet on Chicago Cubs vs. San Francisco Giants on FanDuel today!

Cubs vs Giants Betting Trends

• The Cubs have been chosen as favorites in 18 games this year and have walked away with the win 13 times (72.2%) in those games.
• Chicago has a record of 2-2 when favored by -166 or more this year.
• The Cubs and their opponents have hit the over in 23 of their 35 games with a total set by oddsmakers this season.
• In 35 games with a line this season, the Cubs have a mark of 19-16-0 against the spread.
• The Giants have been the underdog on the moneyline 14 total times this season. They've finished 7-7 in those games.
• San Francisco has played as a moneyline underdog of +140 or longer in just two games this season, which it lost both.
• The Giants have played in 37 games with an over/under set, and have combined with opponents to go over the total 22 times (22-14-1).
• The Giants have an 18-19-0 record ATS this season (covering 48.6% of the time).

Cubs Player Leaders

• Kyle Tucker leads Chicago with 42 hits and an OBP of .399 this season. He has a .290 batting average and a slugging percentage of .559.
• Among all qualifying batters in MLB, he is 30th in batting average, ninth in on-base percentage, and 11th in slugging.
• Pete Crow-Armstrong is batting .264 with 10 doubles, a triple, nine home runs and seven walks. He's slugging .535 with an on-base percentage of .303.
• Among qualifying batters, his batting average places him 56th, his on-base percentage 108th, and his slugging percentage 18th.
• Carson Kelly is batting .355 with a .806 slugging percentage and 23 RBI this year.
• Ian Happ leads Chicago in slugging percentage (.396) thanks to 12 extra-base hits.

Giants Player Leaders

• Jung Hoo Lee has racked up 43 hits with a .507 slugging percentage, both team-high marks for the Giants. He's batting .312 and with an on-base percentage of .364.
• He is 14th in batting average, 41st in on-base percentage and 25th in slugging percentage among all qualifying hitters in the majors.
• Matt Chapman has five doubles, seven home runs and 28 walks while hitting .225. He's slugging .426 with an on-base percentage of .363.
• Including all qualified hitters, he is 116th in batting average, 43rd in on-base percentage and 67th in slugging percentage.
• Michael Yastrzemski has put up a team-high .385 on-base percentage.
• Wilmer Flores is batting .240 with two doubles, seven home runs and nine walks.

Cubs vs Giants Head to Head

• 5/6/2025: 14-5 SF (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 5/5/2025: 9-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/27/2024: 5-3 CHC (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/26/2024: 4-3 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/25/2024: 5-1 SF (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 6/24/2024: 5-4 SF (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 6/19/2024: 6-5 CHC (Favorite: Cubs, Spread: -1.5, Total: 11, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 6/18/2024: 5-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/17/2024: 7-6 SF (Favorite: Cubs, Spread: -1.5, Total: 10.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/6/2023: 8-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 11, Favorite Moneyline: -152, Underdog Moneyline: +128)

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