Colorado vs Delaware Prediction, Odds, Picks, Best Bets for Week 2 2025

The Colorado Buffaloes will take on the Delaware Fightin' Blue Hens in college football action on Saturday.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Colorado vs Delaware Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Colorado: (-3030) | Delaware: (+1200)
• Spread: Colorado: -23.5 (-122) | Delaware: +23.5 (100)
• Total: 49.5 -- Over: (-110) | Under: (-110)

Colorado vs Delaware Betting Trends

• Colorado has no wins against the spread this season.
• Delaware has no wins against the spread this year.
• Delaware and its opponent have yet to go over the total this season.

Colorado vs Delaware Point Spread

Colorado is a 23.5-point favorite against Delaware. Colorado is -122 to cover the spread, and Delaware is +100.

Colorado vs Delaware Over/Under

The Colorado-Delaware game on Sept. 6 has been given an over/under of 49.5 points. The over is -110 and the under is -110.

Colorado vs Delaware Moneyline

Delaware is the underdog, +1200 on the moneyline, while Colorado is a -3030 favorite.

Colorado vs. Delaware Points Insights

• The Buffaloes had an average implied point total of 32.2 last season, which is 4.8 points lower than their implied total in Saturday's game (37).
• The Fightin' Blue Hens' average implied point total last season (33.1 points) is 20.1 points higher than their implied total in this matchup (13 points).

Colorado vs. Delaware Game Info

• Game day: Saturday, September 6, 2025
• Game time: 3:30 p.m. ET
• TV channel: FOX
• Location: Boulder, Colorado
• Stadium: Folsom Field

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Check out even more in-depth Colorado vs. Delaware analysis on FanDuel Research.