Blue Jays vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for May 4

Odds updated as of 1:11 p.m.

The Cleveland Guardians will take on the Toronto Blue Jays in MLB action on Sunday.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Guardians vs Blue Jays Game Info

• Cleveland Guardians (19-14) vs. Toronto Blue Jays (16-17)
• Date: Sunday, May 4, 2025
• Time: 1:37 p.m. ET
• Venue: Rogers Centre -- Toronto, Ontario
• Coverage: SNET and CLEG

Guardians vs Blue Jays Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-112) | TOR: (-104)
• Spread: CLE: -1.5 (+146) | TOR: +1.5 (-176)
• Total: 8.5 -- Over: (-102) | Under: (-120)

Guardians vs Blue Jays Probable Starting Pitchers

Probable Pitchers: Tanner Bibee (Guardians) - 2-2, 4.36 ERA vs Bowden Francis (Blue Jays) - 2-4, 5.28 ERA

The Guardians will call on Tanner Bibee (2-2) against the Blue Jays and Bowden Francis (2-4). Bibee and his team are 3-2-0 ATS this season when he starts. Bibee's team has been victorious in 66.7% of the games he's started as the moneyline favorite with a record of 2-1. The Blue Jays are 4-2-0 against the spread when Francis starts. The Blue Jays were the moneyline underdog for four Francis starts this season -- they lost each time.

Guardians vs Blue Jays Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Blue Jays win (50.2%)

Guardians vs Blue Jays Moneyline

• Cleveland is the favorite, -112 on the moneyline, while Toronto is a -104 underdog despite being at home.

Guardians vs Blue Jays Spread

• The Guardians are at the Blue Jays and are favored by 1.5 runs on the spread. The Guardians are +146 to cover the runline, with the Blue Jays being -176.

Guardians vs Blue Jays Over/Under

• Guardians versus Blue Jays on May 4 has an over/under of 8.5 runs, with the odds on the over -102 and the under set at -120.

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Guardians vs Blue Jays Betting Trends

• The Guardians have been favorites in 11 games this season and have come away with the win eight times (72.7%) in those contests.
• This season Cleveland has been victorious eight times in 11 chances when named as a favorite of at least -112 on the moneyline.
• The Guardians and their opponents have gone over in 17 of their 32 games with a total set by sportsbooks this season.
• In 32 games with a line this season, the Guardians have a mark of 15-17-0 against the spread.
• The Blue Jays have won 10 of the 22 games they were the moneyline underdog this season (45.5%).
• When playing as a moneyline underdog with odds of -104 or longer, Toronto has gone 7-12 (36.8%).
• The Blue Jays have had an over/under set by oddsmakers 32 times, and have combined with opponents to go over the total in 13 of those games (13-18-1).
• The Blue Jays have a 20-12-0 record ATS this season.

Guardians Player Leaders

• Steven Kwan leads Cleveland OPS (.842) this season. He has a .328 batting average, an on-base percentage of .376, and a slugging percentage of .466.
• Among qualified batters in the majors, he ranks sixth in batting average, 34th in on-base percentage, and 44th in slugging.
• Kwan will look for his third straight game with a hit in this matchup. During his last five outings he is hitting .238 with a double and a walk.
• Jose Ramirez has five doubles, five home runs and nine walks. He's batting .274 and slugging .451 with an on-base percentage of .323.
• Among qualified hitters, his batting average ranks him 48th, his on-base percentage 82nd, and his slugging percentage 50th.
• Ramirez heads into this matchup looking to extend his three-game hit streak. During his last five outings he is hitting .333 with a double and an RBI.
• Kyle Manzardo leads Cleveland in total hits (21) this season, and 12 of those have gone for extra bases.
• Carlos Santana has been key for Cleveland with 25 hits, an OBP of .313 plus a slugging percentage of .324.

Blue Jays Player Leaders

• Vladimir Guerrero Jr. is hitting .272 with six doubles, four home runs and 16 walks. He's slugging .416 with an on-base percentage of .357.
• Including all qualifying hitters in the majors, his batting average puts him 52nd, his on-base percentage ranks 45th, and he is 78th in slugging.
• Guerrero hopes to build on a six-game hitting streak in this matchup. In his last 10 games he is batting .231 with three home runs, two walks and seven RBI.
• George Springer's 29 hits and .426 OBP are both team-highs. He has a batting average of .322 while slugging .533.
• He is currently 11th in batting average, fourth in on-base percentage and 18th in slugging percentage among all qualifying hitters.
• Bo Bichette has a .376 slugging percentage, which paces the Blue Jays.
• Andres Gimenez has four doubles, three home runs and 10 walks while hitting .179.

Guardians vs Blue Jays Head to Head

• 5/3/2025: 5-3 CLE (Favorite: Blue Jays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 5/2/2025: 5-3 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/23/2024: 6-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/22/2024: 6-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/21/2024: 7-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/16/2024: 7-6 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/15/2024: 5-0 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/14/2024: 3-1 CLE (Favorite: Blue Jays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/27/2023: 10-7 CLE (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 8/26/2023: 8-3 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8, Favorite Moneyline: -180, Underdog Moneyline: +152)

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