Blue Jays vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for April 23

Odds updated as of 7:11 p.m.

Wednesday's slate in the MLB includes a matchup between the Toronto Blue Jays and the Houston Astros.

All the info you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Blue Jays vs Astros Game Info

• Toronto Blue Jays (12-12) vs. Houston Astros (12-11)
• Date: Wednesday, April 23, 2025
• Time: 7:40 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: MLB Network, SCHN2, and SN1

Blue Jays vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TOR: (-116) | HOU: (-102)
• Spread: TOR: -1.5 (+146) | HOU: +1.5 (-178)
• Total: 8 -- Over: (-115) | Under: (-105)

Blue Jays vs Astros Probable Starting Pitchers

Probable Pitchers: Bowden Francis (Blue Jays) - 2-2, 3.13 ERA vs Ryan Gusto (Astros) - 2-1, 3.18 ERA

The Blue Jays will give the nod to Bowden Francis (2-2, 3.13 ERA), who is eyeing win No. 3 on the season, and the Astros will turn to Ryan Gusto (2-1, 3.18 ERA). Francis and his team have covered in each of the four games he's started with a spread this season. Francis' team is 2-0 this season when he starts and they're favored on the moneyline. Gusto has started two games with set spreads, and the Astros went 1-1-0. The Astros have not been a moneyline underdog when Gusto starts this season.

Blue Jays vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (59.2%)

Blue Jays vs Astros Moneyline

• Toronto is a -116 favorite on the moneyline, while Houston is a -102 underdog at home.

Blue Jays vs Astros Spread

• The Astros are +1.5 on the spread (-178 to cover), and Toronto is +146 to cover the runline.

Blue Jays vs Astros Over/Under

• An over/under of 8 has been set for Blue Jays-Astros on April 23, with the over being -115 and the under -105.

Bet on Toronto Blue Jays vs. Houston Astros on FanDuel today!

Blue Jays vs Astros Betting Trends

• The Blue Jays have come away with five wins in the eight contests they have been listed as the favorites in this season.
• This year Toronto has won five of eight games when listed as at least -116 on the moneyline.
• The Blue Jays and their opponents have hit the over in nine of their 24 games with a total set by oddsmakers this season.
• The Blue Jays are 16-8-0 against the spread in their 24 games with a line set by sportsbooks this season.
• The Astros have a 5-4 record in games they were listed as the moneyline underdog (winning 55.6% of those games).
• When playing as a moneyline underdog with odds of -102 or longer, Houston has gone 3-3 (50%).
• The Astros have had an over/under set by oddsmakers 23 times, and have combined with opponents to go over the total in eight of those games (8-13-2).
• The Astros have collected a 13-10-0 record ATS this season (covering 56.5% of the time).

Blue Jays Player Leaders

• Bo Joseph Bichette has an OPS of .714, fueled by an OBP of .339 and a team-best slugging percentage of .375 this season. He has a .298 batting average.
• Among qualified hitters in the majors, he ranks 33rd in batting average, 71st in on-base percentage, and 102nd in slugging.
• Vladimir Guerrero Jr. is batting .278 with six doubles, a home run and 14 walks, while slugging .378 with an on-base percentage of .377.
• Among qualified hitters, his batting average ranks him 53rd, his on-base percentage 31st, and his slugging percentage 100th.
• Andres Gimenez has 17 hits this season and has a slash line of .189/.275/.333.
• George Springer has 22 hits and an OBP of .416, both of which lead the Blue Jays this season.

Astros Player Leaders

• Jeremy Pena is hitting .253 with three doubles, three home runs and eight walks. He's slugging .398 with an on-base percentage of .330.
• Including all the qualifying hitters in the majors, his batting average puts him 78th, his on-base percentage ranks 81st, and he is 93rd in slugging.
• Pena enters this matchup on a 13-game hitting streak. During his last 10 outings he is hitting .324 with two doubles, a home run, three walks and five RBI.
• Isaac Paredes has a .340 OBP to lead his team. He has a batting average of .233 while slugging .384.
• He ranks 99th in batting average, 70th in on-base percentage and 99th in slugging percentage in the big leagues.
• Jose Carlos Altuve has put up a team-high slugging percentage (.415) while leading the Astros in hits (28).
• Yordan Ruben Alvarez has three doubles, two home runs and 13 walks while hitting .213.

Blue Jays vs Astros Head to Head

• 4/22/2025: 5-1 HOU (Favorite: Blue Jays, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/21/2025: 7-0 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/4/2024: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/3/2024: 9-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/2/2024: 7-6 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/1/2024: 3-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/3/2024: 8-0 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/2/2024: 2-1 TOR (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 4/1/2024: 10-0 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 6/8/2023: 3-2 TOR (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)

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