Astros vs Rays Prediction, Odds, Moneyline, Spread & Over/Under for May 29

Odds updated as of 7:11 p.m.

The Thursday slate in MLB includes a matchup between the Houston Astros and the Tampa Bay Rays.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Astros vs Rays Game Info

• Houston Astros (30-25) vs. Tampa Bay Rays (28-27)
• Date: Thursday, May 29, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and FDSSUN

Astros vs Rays Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-116) | TB: (-102)
• Spread: HOU: +1.5 (-192) | TB: -1.5 (+158)
• Total: 8.5 -- Over: (+102) | Under: (-124)

Astros vs Rays Probable Starting Pitchers

Probable Pitchers: Ryan Gusto (Astros) - 3-2, 4.58 ERA vs Shane Baz (Rays) - 4-3, 4.94 ERA

The Astros will give the nod to Ryan Gusto (3-2, 4.58 ERA), who is eyeing win No. 4 on the season, and the Rays will counter with Shane Baz (4-3, 4.94 ERA). Gusto and his team have a record of 3-3-0 against the spread when he starts. When Gusto starts a game and his team is the favorite on the moneyline, they have a record of 3-3. The Rays are 6-4-0 against the spread when Baz starts. The Rays have been the underdog on the moneyline in three of Baz's starts this season, and they went 2-1 in those matchups.

Astros vs Rays Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (54%)

Astros vs Rays Moneyline

• Tampa Bay is a -102 underdog on the moneyline, while Houston is a -116 favorite at home.

Astros vs Rays Spread

• The Rays are 1.5-run favorites against the spread for this matchup with the Astros. The Rays are +158 to cover, while the Astros are -192 to cover as a 1.5-run underdog on the runline.

Astros vs Rays Over/Under

• A total of 8.5 runs has been set for the Astros-Rays game on May 29, with the over available at +102 and the under at -124.

Bet on Houston Astros vs. Tampa Bay Rays on FanDuel today!

Astros vs Rays Betting Trends

• The Astros have been chosen as favorites in 36 games this year and have walked away with the win 20 times (55.6%) in those games.
• Houston has a record of 19-15 when favored by -116 or more this year.
• The Astros' games have gone over the total in 22 of their 55 opportunities.
• The Astros are 31-24-0 against the spread in their 55 games that had a posted line this season.
• The Rays have compiled an 11-12 record in games they were listed as the moneyline underdog (winning 47.8% of those games).
• In games it has played as a moneyline underdog with odds of -102 or longer, Tampa Bay has gone 11-11 (50%).
• The Rays have played in 54 games with a set over/under, and have combined with their opponents to go over the total 20 times (20-31-3).
• The Rays have put together a 26-28-0 record against the spread this season.

Astros Player Leaders

• Isaac Paredes leads Houston in OBP (.369) and total hits (54) this season. He's batting .267 batting average while slugging .475.
• He ranks 62nd in batting average, 30th in on-base percentage, and 40th in slugging among all qualifying hitters in the majors.
• Jeremy Pena leads Houston in slugging percentage (.445) thanks to 16 extra-base hits. He's batting .297 with an on-base percentage of .363.
• Among all qualified hitters, he is 16th in batting average, 34th in on-base percentage and 59th in slugging percentage.
• Pena has picked up at least one hit in four games in a row. In his last five games he is batting .286 with a home run, two walks and two RBIs.
• Jose Altuve is batting .267 with a .410 slugging percentage and 21 RBI this year.
• Jake Meyers is batting .293 with a .353 OBP and 16 RBI for Houston this season.

Rays Player Leaders

• Jonathan Aranda has accumulated 52 hits with a .397 on-base percentage and a .503 slugging percentage, all club-bests for the Rays. He's batting .315.
• Including all qualifying hitters, he ranks ninth in batting average, while his on-base percentage is eighth and he is 28th in slugging.
• Aranda heads into this matchup on a four-game hitting streak. In his last five games he is batting .389 with a double, a home run, two walks and six RBIs.
• Yandy Diaz is hitting .233 with 10 doubles, seven home runs and 13 walks. He's slugging .383 with an on-base percentage of .279.
• He is 123rd in batting average, 145th in on-base percentage and 112th in slugging percentage in the majors.
• Junior Caminero is hitting .249 with 10 doubles, 10 home runs and nine walks.
• Brandon Lowe has five doubles, 11 home runs and 14 walks while batting .249.

Astros vs Rays Head to Head

• 5/21/2025: 8-4 TB (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/20/2025: 3-2 TB (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/19/2025: 4-3 HOU (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/14/2024: 2-1 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/13/2024: 3-2 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/12/2024: 6-1 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/4/2024: 1-0 TB (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 8/3/2024: 6-1 TB (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/2/2024: 3-2 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/30/2023: 8-2 TB (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!