Astros vs Rays Prediction, Odds, Moneyline, Spread & Over/Under for May 20

Odds updated as of 7:11 p.m.

In MLB action on Tuesday, the Tampa Bay Rays take on the Houston Astros.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information regarding this matchup.

Rays vs Astros Game Info

• Tampa Bay Rays (21-26) vs. Houston Astros (25-22)
• Date: Tuesday, May 20, 2025
• Time: 7:05 p.m. ET
• Venue: George M. Steinbrenner Field -- Tampa, Florida
• Coverage: FDSSUN and SCHN

Rays vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-136) | HOU: (+116)
• Spread: TB: -1.5 (+146) | HOU: +1.5 (-176)
• Total: 9 -- Over: (-122) | Under: (-100)

Rays vs Astros Probable Starting Pitchers

Probable Pitchers: Zack Littell (Rays) - 3-5, 4.31 ERA vs Brandon Walter (Astros) - 0-0, 0.00 ERA

The probable starters are Zack Littell (3-5) for the Rays and Brandon Walter for the Astros. Littell and his team are 4-5-0 ATS this season when he starts. Littell's team has been victorious in 25% of the games he's started as the moneyline favorite with a record of 1-3. Walter's team was never a moneyline underdog a season ago in games he pitched.

Rays vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (55.9%)

Rays vs Astros Moneyline

• Tampa Bay is the favorite, -136 on the moneyline, while Houston is a +116 underdog on the road.

Rays vs Astros Spread

• The Astros are +1.5 on the run line against the Rays. The Astros are -176 to cover, and the Rays are +146.

Rays vs Astros Over/Under

• Rays versus Astros, on May 20, has an over/under of 9, with the over being -122 and the under -100.

Bet on Tampa Bay Rays vs. Houston Astros on FanDuel today!

Rays vs Astros Betting Trends

• The Rays have been victorious in 11, or 45.8%, of the 24 contests they have been chosen as favorites in this season.
• This season Tampa Bay has been victorious seven times in 15 chances when named as a favorite of at least -136 on the moneyline.
• The Rays and their opponents have hit the over in 18 of their 46 games with a total set by oddsmakers this season.
• The Rays have an against the spread mark of 20-26-0 in 46 games with a line this season.
• The Astros have won 50% of the games this season they were the moneyline underdog (7-7).
• In games it has played as a moneyline underdog with odds of +116 or longer, Houston has a record of 2-1 (66.7%).
• The Astros have played in 47 games with an over/under set, and have combined with opponents to go over the total 19 times (19-26-2).
• The Astros have covered 53.2% of their games this season, going 25-22-0 against the spread.

Rays Player Leaders

• Yandy Diaz leads Tampa Bay with a slugging percentage of .401, fueled by 15 extra-base hits. He has a .249 batting average and an on-base percentage of .297.
• Among qualifying hitters in the majors, he ranks 94th in batting average, 123rd in on-base percentage, and 95th in slugging.
• Diaz hopes to build on a four-game hitting streak in this matchup. During his last five outings he is hitting .286 with a double and four RBIs.
• Jonathan Aranda has 43 hits and an OBP of .394, both of which lead the Rays this season. He's batting .309 and slugging .504.
• Among all qualified hitters, he ranks 11th in batting average, 10th in on-base percentage and 25th in slugging percentage.
• Junior Caminero is batting .235 with a .412 slugging percentage and 20 RBI this year.
• Brandon Lowe has seven home runs, 24 RBI and a batting average of .218 this season.
• Lowe enters this game on a three-game hitting streak. In his last five games he is batting .300 with two home runs, two walks and four RBIs.

Astros Player Leaders

• Jeremy Pena has put up a slugging percentage of .455 and has 55 hits, both team-high numbers for the Astros. He's batting .309 and with an on-base percentage of .362.
• He is 11th in batting average, 47th in on-base percentage and 55th in slugging percentage among all qualified batters in the majors.
• Isaac Paredes has a .375 OBP to pace his team. He has a batting average of .265 while slugging .435.
• Including all qualifying hitters, he is 65th in batting average, 26th in on-base percentage and 71st in slugging percentage.
• Jake Meyers is batting .301 with six doubles, a triple, three home runs and 15 walks.
• Jose Altuve is hitting .236 with six doubles, four home runs and 14 walks.

Rays vs Astros Head to Head

• 5/19/2025: 4-3 HOU (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/14/2024: 2-1 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/13/2024: 3-2 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/12/2024: 6-1 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/4/2024: 1-0 TB (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 8/3/2024: 6-1 TB (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/2/2024: 3-2 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/30/2023: 8-2 TB (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/29/2023: 17-4 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 7/28/2023: 4-3 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

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