Astros vs Rays Prediction, Odds, Moneyline, Spread & Over/Under for May 20

Odds updated as of 7:11 a.m.

The Houston Astros versus the Tampa Bay Rays is on the MLB schedule for Tuesday.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Astros vs Rays Game Info

• Houston Astros (25-22) vs. Tampa Bay Rays (21-26)
• Date: Tuesday, May 20, 2025
• Time: 7:05 p.m. ET
• Venue: George M. Steinbrenner Field -- Tampa, Florida
• Coverage: FDSSUN and SCHN

Astros vs Rays Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-116) | TB: (-102)
• Spread: HOU: -1.5 (+140) | TB: +1.5 (-170)
• Total: 9.5 -- Over: (-110) | Under: (-110)

Astros vs Rays Probable Starting Pitchers

Probable Pitchers: Brandon Walter (Astros) - 0-0, 0.00 ERA vs Zack Littell (Rays) - 3-5, 4.31 ERA

The probable pitchers are Brandon Walter for the Astros and Zack Littell (3-5) for the Rays. Walter did not pitch as the moneyline favorite last season. The Rays have a 4-5-0 record against the spread in Littell's starts. The Rays have been the moneyline underdog in five of Littell's starts this season, and they went 3-2 in those games.

Astros vs Rays Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (54.1%)

Astros vs Rays Moneyline

• Tampa Bay is the underdog, -102 on the moneyline, while Houston is a -116 favorite despite being on the road.

Astros vs Rays Spread

• The Rays are hosting the Astros, and are +1.5 on the runline. The Rays are +140 to cover the spread, and the Astros are -170.

Astros vs Rays Over/Under

• The over/under for the Astros versus Rays contest on May 20 has been set at 9.5, with -110 odds on the over and -110 odds on the under.

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Astros vs Rays Betting Trends

• The Astros have come away with 18 wins in the 32 contests they have been listed as the favorites in this season.
• Houston has a record of 17-13 in contests when oddsmakers favor them by -116 or more on the moneyline.
• The Astros and their opponents have hit the over in 19 of their 47 games with a total set by oddsmakers this season.
• The Astros have an against the spread mark of 25-22-0 in 47 games with a line this season.
• The Rays have a 10-11 record in games they were listed as the moneyline underdog (winning 47.6% of those games).
• Tampa Bay has gone 10-10 in games it has played as a moneyline underdog with odds of -102 or longer (50%).
• The Rays have played in 46 games with a set over/under, and have combined with opponents to go over the total 18 times (18-26-2).
• The Rays have put together a 20-26-0 record ATS this season (covering 43.5% of the time).

Astros Player Leaders

• Jeremy Pena leads Houston with 55 hits and a team-best slugging percentage of .455. He's batting .309 with an on-base percentage of .362.
• Among qualified hitters in the majors, his batting average ranks 11th, his on-base percentage ranks 47th, and he is 55th in slugging.
• Isaac Paredes leads Houston with an OBP of .375 this season while batting .265 with 28 walks and 22 runs scored. He's slugging .435.
• He ranks 65th in batting average, 26th in on-base percentage and 71st in slugging among qualifying batters.
• Paredes brings a four-game streak with at least one hit into this one. In his last five games he is batting .250 with a home run, a walk and five RBIs.
• Jake Meyers has 41 hits this season and has a slash line of .301/.368/.426.
• Meyers has logged a hit or more in four games in a row. During his last five outings he is hitting .313 with a home run, three walks and an RBI.
• Jose Altuve is batting .236 with a .290 OBP and 14 RBI for Houston this season.

Rays Player Leaders

• Yandy Diaz has accumulated a team-best .401 slugging percentage. He's batting .249 with an on-base percentage of .297.
• Including all the qualified players in the majors, his batting average is 94th, his on-base percentage ranks 123rd, and he is 95th in slugging.
• Diaz brings a four-game hitting streak into this game. During his last five outings he is hitting .286 with a double and four RBIs.
• Jonathan Aranda's 43 hits and .394 on-base percentage both pace his team. He has a batting average of .309 while slugging .504.
• Including all qualifying hitters, he is 11th in batting average, 10th in on-base percentage and 25th in slugging percentage.
• Junior Caminero has six doubles, eight home runs and eight walks while hitting .235.
• Brandon Lowe has two doubles, seven home runs and 13 walks while batting .218.

Astros vs Rays Head to Head

• 5/19/2025: 4-3 HOU (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/14/2024: 2-1 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/13/2024: 3-2 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/12/2024: 6-1 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/4/2024: 1-0 TB (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 8/3/2024: 6-1 TB (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/2/2024: 3-2 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/30/2023: 8-2 TB (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/29/2023: 17-4 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 7/28/2023: 4-3 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

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