Astros vs Brewers Prediction, Odds, Moneyline, Spread & Over/Under for May 7

Odds updated as of 10:11 a.m.

The Houston Astros will take on the Milwaukee Brewers in MLB action on Wednesday.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Astros vs Brewers Game Info

• Houston Astros (17-18) vs. Milwaukee Brewers (19-18)
• Date: Wednesday, May 7, 2025
• Time: 1:10 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: MLB Network, FDSWI, and SCHN

Astros vs Brewers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-134) | MIL: (+114)
• Spread: HOU: -1.5 (+126) | MIL: +1.5 (-152)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Astros vs Brewers Probable Starting Pitchers

Probable Pitchers: Framber Valdez (Astros) - 1-4, 4.39 ERA vs Quinn Priester (Brewers) - 1-0, 5.79 ERA

This contest's pitching matchup is set, as the Astros will send Framber Valdez (1-4) to the mound, while Quinn Priester (1-0) will answer the bell for the Brewers. Valdez's team is 3-4-0 against the spread this season in his starts. Valdez's team has won 16.7% of his starts when they are favored on the moneyline (1-5). The Brewers are 2-2-0 ATS in Priester's four starts with a set spread. The Brewers have a 1-2 record in Priester's three starts this season when they were the underdog on the moneyline.

Astros vs Brewers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (58.7%)

Astros vs Brewers Moneyline

• The Astros vs Brewers moneyline has Houston as a -134 favorite, while Milwaukee is a +114 underdog at home.

Astros vs Brewers Spread

• The Astros are favored by 1.5 runs on the road versus the Brewers. The Astros are +126 to cover the spread, while the Brewers are -152.

Astros vs Brewers Over/Under

• The Astros-Brewers contest on May 7 has been given an over/under of 7.5 runs. The over is set at -115 and the under at -105.

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Astros vs Brewers Betting Trends

• The Astros have won in 12, or 50%, of the 24 contests they have been named as odds-on favorites in this year.
• This year Houston has won seven of 13 games when listed as at least -134 on the moneyline.
• The Astros and their opponents have gone over in 15 of their 35 games with a total set by sportsbooks this season.
• The Astros have an against the spread mark of 19-16-0 in 35 games with a line this season.
• The Brewers have won four of the 17 games they were listed as the moneyline underdog this season (23.5%).
• Milwaukee has a 2-9 record (winning just 18.2% of its games) when playing as a moneyline underdog of +114 or longer.
• The Brewers have combined with opponents to go over the total 15 times this season for a 15-21-1 record against the over/under.
• The Brewers have put together a 21-16-0 record ATS this season (covering 56.8% of the time).

Astros Player Leaders

• Jeremy Pena leads Houston with 36 hits and a team-best slugging percentage of .405. He's batting .275 with an on-base percentage of .338.
• Among qualified hitters, he is 43rd in batting average, his on-base percentage ranks 63rd, and he is 86th in slugging.
• Isaac Paredes leads Houston in OBP (.361) this season, fueled by 32 hits. He's batting .254 while slugging .389.
• Among qualifying hitters, his batting average ranks him 74th, his on-base percentage 46th, and his slugging percentage 100th.
• Jose Altuve is batting .254 with a .370 slugging percentage and 14 RBI this year.
• Jake Meyers has been key for Houston with 29 hits, an OBP of .349 plus a slugging percentage of .433.
• Meyers heads into this game on a seven-game hitting streak. In his last 10 outings he is hitting .367 with a double, a triple, two home runs, three walks and eight RBIs.

Brewers Player Leaders

• Jackson Chourio has put up 41 hits, a team-best for the Brewers. He's batting .261 and slugging .471 with an on-base percentage of .273.
• Including all qualifying hitters in MLB, he ranks 63rd in batting average, 134th in on-base percentage and 42nd in slugging percentage.
• Chourio hopes to build on a four-game hitting streak in this matchup. During his last five outings he is hitting .250 with two doubles.
• Brice Turang leads his team with a .383 on-base percentage, and has a club-leading .409 slugging percentage. He has a batting average of .318.
• He is currently eighth in batting average, 24th in on-base percentage and 81st in slugging percentage among all qualified hitters.
• William Contreras has two doubles, three home runs and 23 walks while batting .242.
• Sal Frelick has five doubles, two triples, a home run and 13 walks while batting .297.

Astros vs Brewers Head to Head

• 5/6/2025: 4-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/5/2025: 5-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/19/2024: 9-4 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 5/18/2024: 4-2 MIL (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 5/17/2024: 5-4 HOU (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/24/2023: 4-0 MIL (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/23/2023: 6-0 MIL (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/22/2023: 12-2 HOU (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)

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