Monday Night Football Fantasy Picks: Start 'Em, Sit' Em for Seattle Seahawks vs San Francisco 49ers

If you still have players on your fantasy team yet to play their Week 10 game, it means that the "Monday Night Football" matchup between the Seattle Seahawks and San Francisco 49ers will likely determine whether you're coming away with a win or not. There's no room for error when it comes to your starting lineup, specifically if you have multiple options for the game.

With that in mind, here's some start 'em, sit 'em advice for Monday's matchup between the division-rival Seahawks and 49ers.

MNF Fantasy Football

Start Tevin Coleman and Matt Breida, RB, San Francisco 49ers: Seattle's defense has been nothing to write home about this season, allowing the NFL's 11th-most points per game (PPG), and those struggles extend to their run defense, where they rank just 22nd in Football Outsiders' DVOA rankings. Coleman is averaging 16.3 PPR fantasy points per game since returning to action in Week 5, and should be considered an every-week starter. Even as the No. 2 RB, Matt Breida has averaged a solid 13.8 opportunities (11.6 carries plus 2.2 targets) per game in that time, which he has turned into an average of 12.0 fantasy points per game of his own. Both are fantasy viable on Monday night.

Start Jimmy Garoppolo, QB, San Francisco 49ers: Another symptom of the Seahawks' defensive struggles is that they've allowed the NFL's 12th-most fantasy points per game (18.9) to opposing QBs. Jimmy Garoppolo is averaging an underwhelming 14.7 fantasy points per game in 2019, but that average jumps to 19.2 per game in his four contests against teams that give up top-12 fantasy numbers to QBs.

Sit DK Metcalf, WR, Seattle Seahawks: DK Metcalf is coming off a massive 123-yard, one-TD game in Week 9, but this matchup could prove too much to overcome for the rookie. The 49ers are the second-ranked defense in Football Outsiders' DVOA rankings, and they're the top-ranked unit against the pass. They're holding opposing wideouts to the NFL's sixth-fewest fantasy points per game, and while that doesn't take No. 1 WR Tyler Lockett out of play, it's going to be tough for Seattle to support two fantasy-relevant wideouts in Week 10.

Sit Jacob Hollister, TE, Seattle Seahawks: Will Dissly's early-season success feels like a distant memory at this point, but Jacob Hollister has finally filled his role with some solid numbers. He notched 19.7 PPR fantasy points in Week 9, but he stands to come crashing back down to earth on Monday. His six targets in that game accounted for just 14.0 percent of the team's total, and with low volume he can't be expected to do much against San Francisco. The 49ers' terrific pass defense has been especially stingy against tight ends, giving up a league-low 5.7 PPR points per game to the position.

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Jason Schandl is not a FanDuel employee. In addition to providing DFS gameplay advice, Jason Schandl also participates in DFS contests on FanDuel using his personal account, username Jaymun. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.