Yankees vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 23

Odds updated as of 5:11 p.m.

Thursday's slate in the MLB includes a matchup between the New York Yankees and the Boston Red Sox.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Yankees vs Red Sox Game Info

• New York Yankees (15-9) vs. Boston Red Sox (9-15)
• Date: Thursday, April 23, 2026
• Time: 6:10 p.m. ET
• Venue: Fenway Park -- Boston, Massachusetts
• Coverage: FS1, NESN+, and YES

Yankees vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-144) | BOS: (+122)
• Spread: NYY: -1.5 (+118) | BOS: +1.5 (-142)
• Total: 7.5 -- Over: (-108) | Under: (-112)

Yankees vs Red Sox Probable Starting Pitchers

Probable Pitchers: Cam Schlittler (Yankees) - 2-1, 1.95 ERA vs Payton Tolle (Red Sox) - 0-0, 0.00 ERA

The Yankees will give the nod to Cam Schlittler (2-1, 1.95 ERA), who is eyeing win No. 3 on the season, and the Red Sox will turn to Payton Tolle. Schlittler and his team are 4-1-0 ATS this season when he starts. When Schlittler starts a game and his team is the favorite on the moneyline, they have a record of 3-1. Last season (in three games pitched with a spread) Tolle and his team failed to cover the spread each time. Tolle and his team were underdogs on the moneyline each game he pitched a season ago.

Yankees vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (63.2%)

Yankees vs Red Sox Moneyline

• Looking at the moneyline for Yankees-Red Sox, New York is the favorite at -144, and Boston is +122 playing at home.

Yankees vs Red Sox Spread

• The Yankees are at the Red Sox and are favored by 1.5 runs on the spread. The Yankees are +118 to cover the runline, with the Red Sox being -142.

Yankees vs Red Sox Over/Under

• The over/under for the Yankees versus Red Sox contest on April 23 has been set at 7.5, with -108 odds on the over and -112 odds on the under.

Bet on New York Yankees vs. Boston Red Sox on FanDuel today!

Yankees vs Red Sox Betting Trends

• The Yankees have been chosen as favorites in 20 games this year and have walked away with the win 12 times (60%) in those games.
• New York has a record of 7-6 in contests when oddsmakers favor them by -144 or more on the moneyline.
• The Yankees and their opponents have gone over the total this season in eight of their 22 opportunities.
• The Yankees have posted a record of 12-10-0 against the spread this season.
• The Red Sox have yet to win as the moneyline underdog this season, going 2-0.
• Boston has played as a moneyline underdog of +122 or longer in only one game this season, which it lost.
• The Red Sox have had an over/under set by bookmakers 24 times, and have combined with opponents to go over the total in 12 of those games (12-12-0).
• The Red Sox are 7-17-0 against the spread this season.

Yankees Player Leaders

• Ben Rice has 22 hits and an OBP of .456 to go with a slugging percentage of .743. All three of those stats lead New York hitters this season. He has a .314 batting average, as well.
• Among all qualified hitters in the majors, his batting average ranks 15th, his on-base percentage ranks second, and he is second in slugging.
• Aaron Judge is batting .241 with three doubles, nine home runs and 15 walks, while slugging .586 with an on-base percentage of .359.
• His batting average ranks 97th among qualified players, his on-base percentage 49th, and his slugging percentage 11th.
• Judge heads into this matchup looking to extend his three-game hit streak. In his last five games he is batting .267 with a double, a home run, seven walks and two RBIs.
• Cody Bellinger has an OPS of .804, fueled by an OBP of .370 and a team-best slugging percentage of .434 this season.
• Trent Grisham is batting .162 with a .313 OBP and 14 RBI for New York this season.

Red Sox Player Leaders

• Wilyer Abreu has racked up 25 hits with a .449 slugging percentage, both team-best stats for the Red Sox. He's batting .281 and with an on-base percentage of .333.
• Including all the qualifying hitters in MLB, he ranks 40th in batting average, 83rd in on-base percentage and 53rd in slugging percentage.
• Willson Contreras' .392 on-base percentage leads his team. He has a batting average of .263 while slugging .438.
• Including all qualifying players, he is 64th in batting average, 20th in on-base percentage and 66th in slugging percentage.
• Roman Anthony has three doubles, a triple, a home run and 16 walks while batting .225.
• Jarren Duran has five doubles, a home run and six walks while hitting .194.

Yankees vs Red Sox Head to Head

• 4/22/2026: 4-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/21/2026: 4-0 NYY (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 10/2/2025: 4-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 10/1/2025: 4-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 9/30/2025: 3-1 BOS (Favorite: Yankees, Spread: -1.5, Total: 6.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/14/2025: 6-4 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 9/13/2025: 5-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 9/12/2025: 4-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/24/2025: 7-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 8/23/2025: 12-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

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