Yankees vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for May 7

Odds updated as of 7:11 p.m.

The New York Yankees are among the MLB squads in action on Wednesday, up against the San Diego Padres.

We've got you covered, in terms of the vital info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Yankees vs Padres Game Info

• New York Yankees (20-16) vs. San Diego Padres (23-12)
• Date: Wednesday, May 7, 2025
• Time: 7:05 p.m. ET
• Venue: Yankee Stadium -- The Bronx, New York
• Coverage: MLB Network, Amazon Prime Video, and SDPA

Yankees vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-172) | SD: (+144)
• Spread: NYY: -1.5 (+118) | SD: +1.5 (-142)
• Total: 8 -- Over: (-106) | Under: (-114)

Yankees vs Padres Probable Starting Pitchers

Probable Pitchers: Max Fried (Yankees) - 6-0, 1.01 ERA vs Dylan Cease (Padres) - 1-2, 5.61 ERA

The Yankees will give the ball to Max Fried (6-0, 1.01 ERA), who is eyeing win No. 7 on the season, and the Padres will counter with Dylan Cease (1-2, 5.61 ERA). Fried's team is 6-1-0 against the spread in his starts this season. Fried and his team have won each of the seven games he's started as the moneyline favorite. The Padres have a 3-4-0 ATS record in Cease's seven starts that had a set spread. The Padres were the moneyline underdog for one Cease start this season -- they won.

Yankees vs Padres Moneyline

• Looking at the moneyline for Yankees-Padres, New York is the favorite at -172, and San Diego is +144 playing on the road.

Yankees vs Padres Spread

• The Padres are +1.5 on the spread (-142 to cover), and New York is +118 to cover the runline.

Yankees vs Padres Over/Under

• The Yankees-Padres contest on May 7 has been given an over/under of 8 runs. The over is set at -106 and the under at -114.

Bet on New York Yankees vs. San Diego Padres on FanDuel today!

Yankees vs Padres Betting Trends

• The Yankees have been favorites in 29 games this season and have come away with the win 18 times (62.1%) in those contests.
• This season New York has come away with a win five times in six chances when named as a favorite of at least -172 on the moneyline.
• Contests with the Yankees have gone over the total set by bookmakers in 16 of 35 chances this season.
• In 35 games with a line this season, the Yankees have a mark of 17-18-0 against the spread.
• The Padres have won eight of the 16 games they were listed as the moneyline underdog this season (50%).
• San Diego has not yet played as a moneyline underdog of +144 or longer.
• The Padres have played in 34 games with an over/under set, and have combined with their opponents to go over the total 14 times (14-19-1).
• The Padres have collected a 20-14-0 record ATS this season (covering 58.8% of the time).

Yankees Player Leaders

• Aaron Judge leads New York in OBP (.503), slugging percentage (.772) and total hits (56) this season. He has a .412 batting average.
• Among the qualifying hitters in MLB, his batting average ranks first, his on-base percentage ranks first, and he is first in slugging.
• Paul Goldschmidt is batting .351 with eight doubles, three home runs and 11 walks, while slugging .478 with an on-base percentage of .401.
• Among all qualifying batters, he is second in batting average, eighth in on-base percentage and 35th in slugging percentage.
• Ben Rice has 29 hits this season and has a slash line of .264/.362/.573.
• Rice has picked up a hit in two straight games. During his last five outings he is hitting .250 with four doubles, a walk and two RBIs.
• Trent Grisham has nine home runs, 18 RBI and a batting average of .284 this season.

Padres Player Leaders

• Fernando Tatis Jr. has accumulated 42 hits with a .388 on-base percentage and a .557 slugging percentage, all club-bests for the Padres. He's batting .321.
• Including all the qualified hitters in the big leagues, his batting average puts him seventh, his on-base percentage is 18th, and he is 11th in slugging.
• Manny Machado is hitting .300 with 12 doubles, three home runs and 13 walks. He's slugging .462 with an on-base percentage of .361.
• He is currently 20th in batting average, 45th in on-base percentage and 46th in slugging percentage among all qualifying batters.
• Luis Arraez has four doubles, a triple, three home runs and seven walks while batting .289.
• Xander Bogaerts is batting .246 with nine doubles, a home run and 16 walks.

Yankees vs Padres Head to Head

• 5/6/2025: 12-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/5/2025: 4-3 SD (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/26/2024: 5-2 SD (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/25/2024: 4-1 NYY (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/24/2024: 8-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 7, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/28/2023: 10-7 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/27/2023: 3-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 5/26/2023: 5-1 SD (Favorite: Padres, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)

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