Winthrop vs Charleston Southern College Basketball Prediction, Odds, Picks, Best Bets for Big South Tournament

The No. 2 seed Winthrop Eagles (21-10, 13-3 Big South) take on the No. 7 seed Charleston Southern Buccaneers (15-16, 6-10 Big South) in the Big South tournament Friday at Freedom Hall Civic Center, beginning at 2:30 p.m. ET. Both teams will try to get one step closer to securing an automatic place in the NCAA Tournament.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Winthrop vs. Charleston Southern Game Info and Odds

• Game day: Friday, March 6, 2026
• Game time: 2:30 p.m. ET
• TV channel: ESPN+
• Location: Johnson City, Tennessee
• Arena: Freedom Hall Civic Center

Winthrop vs. Charleston Southern Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Winthrop win (72.6%)

Check out these betting insights and trends before you bet on Friday's Winthrop-Charleston Southern spread (Winthrop -4.5) or total (161.5 points).

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Winthrop vs. Charleston Southern: ATS Betting Stats and Trends

• Winthrop has won 12 games against the spread this season, while failing to cover 16 times.
• Charleston Southern has won 13 games against the spread this season, while failing to cover 15 times.
• Charleston Southern covers the spread when it is a 4.5-point underdog or more 72.7% of the time. That's more often than Winthrop covers as a favorite of 4.5 or more (31.6%).
• Against the spread, the Eagles have fared worse when playing at home, covering four times in 11 home games, and seven times in 16 road games.
• In 2025-26 against the spread, the Buccaneers have a better winning percentage at home (.545, 6-5-0 record) than away (.438, 7-9-0).
• Winthrop has beaten the spread five times in 16 conference games.
• Charleston Southern has five wins against the spread in 16 Big South games this year.

Winthrop vs. Charleston Southern: Moneyline Betting Stats

• Winthrop has been the moneyline favorite in 22 games this season and has come away with the win 17 times (77.3%) in those contests.
• This season, the Eagles have been victorious 15 times in 19 chances when named as a favorite of at least -196 or better on the moneyline.
• Charleston Southern is 5-11 in games it was the underdog on the moneyline (winning 31.2% of those games).
• The Buccaneers are 3-7 (winning just 30% of their games) when playing as a moneyline underdog of +162 or longer.
• The moneyline set for this matchup implies Winthrop has a 66.2% chance of coming away with a victory in the contest.

Winthrop vs. Charleston Southern Head-to-Head Comparison

• Winthrop outscores opponents by 9.3 points per game (scoring 84.2 per game to rank 25th in college basketball while giving up 74.9 per outing to rank 217th in college basketball) and has a +286 scoring differential overall.
• Logan Duncomb is 77th in the nation with a team-high 18.4 points per game.
• Charleston Southern outscores opponents by 3.6 points per game (posting 83.5 points per game, 31st in college basketball, and giving up 79.9 per outing, 329th in college basketball) and has a +112 scoring differential.
• A'lahn Sumler's team-leading 18.9 points per game rank him 56th in the nation.
• The 36.5 rebounds per game the Eagles average rank 22nd in the country, and are 6.1 more than the 30.4 their opponents collect per contest.
• Duncomb's 9.0 rebounds per game lead the Eagles and rank 36th in college basketball action.
• The Buccaneers prevail in the rebound battle by an average of 4.2 boards. They are recording 37.2 rebounds per game (12th in college basketball) compared to their opponents' 33.0.
• Brycen Blaine leads the Buccaneers with 7.3 rebounds per game (121st in college basketball).
• Winthrop's 102.7 points per 100 possessions on offense rank 69th in college basketball, and the 91.5 points it allows per 100 possessions rank 82nd in college basketball.
• The Buccaneers average 97.5 points per 100 possessions on offense (188th in college basketball), and allow 93.3 points per 100 possessions (131st in college basketball).

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