Washington vs USC College Basketball Prediction, Odds, Picks, Best Bets for Big Ten Tournament

The No. 12 seed Washington Huskies (15-16, 7-13 Big Ten) head into the Big Ten tournament against the No. 13 seed USC Trojans (18-13, 7-13 Big Ten) on Wednesday at United Center, beginning at 2:30 p.m. ET.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Washington vs. USC Game Info and Odds

• Game day: Wednesday, March 11, 2026
• Game time: 2:30 p.m. ET
• TV channel: Peacock
• Location: Chicago, Illinois
• Arena: United Center

Washington vs. USC Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Washington win (64.2%)

Before you bet on Wednesday's Washington-USC spread (Washington -5.5) or total (152.5 points), see the betting insights and trends below.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Washington vs. USC: ATS Betting Stats and Trends

• Washington has compiled an 18-13-0 record against the spread this season.
• USC has put together a 13-17-0 record against the spread this season.
• When the spread is set as 5.5 or more this season, Washington (7-5) covers a higher percentage of those games when it is the favorite (58.3%) than USC (4-6) does as the underdog (40%).
• Against the spread, the Huskies have played worse when playing at home, covering nine times in 16 home games, and eight times in 13 road games.
• The Trojans have performed better against the spread on the road (5-6-0) than at home (6-9-0) this season.
• Washington has covered the spread 13 times in 20 conference games.
• USC is 8-12-0 against the spread in Big Ten games this year.

Washington vs. USC: Moneyline Betting Stats

• Washington has won in 12, or 75%, of the 16 contests it has been named as the moneyline favorite in this year.
• This year, the Huskies have won nine of 11 games when listed as at least -230 or better on the moneyline.
• USC has won 23.1% of the games this season it was the moneyline underdog (3-10).
• When they have played as a moneyline underdog with odds of +188 or longer, the Trojans have a 1-10 record (winning only 9.1% of their games).
• The moneyline set for this matchup implies Washington has a 69.7% chance of coming away with a victory in the contest.

Washington vs. USC Head-to-Head Comparison

• Last year, Washington was 243rd in the country on offense (71.6 points scored per game) and 283rd on defense (75.5 points conceded).
• With 30 rebounds per game and 31.6 rebounds allowed, Washington was 294th and 209th in the nation, respectively, last year.
• With 12.9 assists per game last season, Washington was 227th in the country.
• Last year, Washington was 232nd in college basketball in turnovers committed (11.6 per game) and 166th in turnovers forced (11.4).
• USC was 96th in college basketball last year with 76.7 points per game. At the other end, it ranked 255th with 74.6 points allowed per contest.
• With 29.2 rebounds per game, USC was 325th in college basketball. It allowed 29.1 rebounds per contest, which ranked 56th in college basketball.
• Last year USC ranked 59th in college basketball in assists, dishing out 15.5 per game.
• Last year USC committed 11.8 turnovers per game (246th-ranked in college basketball) and forced 11.9 turnovers per contest (121st-ranked).

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!